Tracheal transplant with a prefabricated microsurgical flap

Icibaci, Alexan; Mello-Filho, Francisco V. de

doi:10.1002/lary.20538

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Tracheal Transplantation1

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2014

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“…Their long-term outcomes for large tracheal defects have been reviewed by Yu et al 115 The free flaps used include radial forearm flap, 115–118 anterolateral thigh flap, 119,120 sternohyoid muscle, 121 and a saphenous corticoperiostal flap. 122 …”

Section: Tracheal Transplantationmentioning

confidence: 99%

Advances in Tracheal Reconstruction

Haykal¹,

Salna

Waddell

et al. 2014

Plastic and Reconstructive Surgery Global Open

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Summary:A recent revival of global interest for reconstruction of long-segment tracheal defects, which represents one of the most interesting and complex problems in head and neck and thoracic reconstructive surgery, has been witnessed. The trachea functions as a conduit for air, and its subunits including the epithelial layer, hyaline cartilage, and segmental blood supply make it particularly challenging to reconstruct. A myriad of attempts at replacing the trachea have been described. These along with the anatomy, indications, and approaches including microsurgical tracheal reconstruction will be reviewed. Novel techniques such as tissue-engineering approaches will also be discussed. Multiple attempts at replacing the trachea with synthetic scaffolds have been met with failure. The main lesson learned from such failures is that the trachea must not be treated as a “simple tube.” Understanding the anatomy, developmental biology, physiology, and diseases affecting the trachea are required for solving this problem.

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