Tracheal juvenile xanthogranuloma in a child

Managing isolated subglottic juvenile xanthogranuloma without tracheostomy: Case report and review of literature

“…The infant in our case report and two other previously published cases 20,21 were managed conservatively without tracheostomy. The patient reported by Naiman et al 21 although doing well initially, had a recurrence of the JXG requiring tracheal reconstruction 6 months after the initial excision. Sahhar et al 20 described another case managed without tracheostomy, however there is no outcome data available.…”

Juvenile xanthogranuloma presenting as a solitary tracheal mass in a child: A case report and literature review

“…Although we archived significant relief of symptoms of respiratory distress, this method caused profound trauma to the child, and could not be successfully decanulated off tracheotomy until 2 months after operation. In summary, we think that preoperatively correct diagnosis of JXG is the prerequisite for choice of optimal method of treatment of this uncommon disease, and that the method described by Naiman [14] may be the best to achieve favorable results with minimum complications.…”

“…In the third case, Sahhar [13] confronted a subglotic laryngeal lesion of JXG and treated baby with laser microlaryngoscopy, and reported favorable result without the need for tracheotomy. However Naiman [14] also used similar laser microlaryngoscopy to treat JXG involving the trachea in the fourth case, but after one and a half-year later, flexible fibroscopy showed a relapse, with 50% occlusion of the tracheal airway. The patient was subsequently managed by external surgical excision without tracheotomy.…”

Prolonged severe pancytopenia preceding the cutaneous lesions of juvenile xanthogranuloma

“…JXG histiocytes can infiltrate into extracutaneous organs including liver, spleen, lung, and CNS 3,4. Of all 22 patients with extracutaneous JXG, a solitary or multiple nodule(s) were clearly identified in the affected site 5.…”

“…The skin lesions exhibit benign morphology on the histopathology and mostly regress spontaneously within several years. Approximately 5% of patients suffer from organ involvement, but the visceral form without skin lesion is very rare 3,4. Systemic JXG may arise during the perinatal period and lead to the aggressive clinical course 5.…”