Trace Quantity Detection of H₂PO₄^– by Fluorescent Metal–Organic Framework (F-MOF) and Bioimaging Study

Abstract

Drinking water quality management and sustainable environment to water bodies are a major concern to public health engineering departments. Inorganic phosphate (Pi), one of the major inorganic pollutants, is addressed for the last two decades regarding trace quantity detection. Over the past few years, a large number of fluorescent metal−organic frameworks (F-MOFs) have been studied to explore the desirable method for selective water analysis. In this article, a Zn− anion by a "turn-off" fluorescent sensing technique. Single-crystal X-ray analysis accounts that the asymmetric unit is constituted of two different Zn(II) centers by PCDF-INH, and the bridging group BDC 2− ions are responsible for the generation of the helical polymer and the biporous structures (14.807 × 13.096 Å 2 and 24.905 × 24.932 Å 2 ). The compound, 1, exhibits strong emission at 505 nm in CH 3 OH−H 2 O solution and is "turn-off" upon the addition of H 2 PO 4 − . The selectivity and specificity for H 2 PO 4 − have been checked in the presence of 15 different anions, including different phosphates (PO 4 3− , HPO 4 2− , P 2 O7 4 − ). The entire sensing activity of 1 is examined by spectrofluorometric method, 1 H NMR titration, PXRD analysis, and bioimaging study, and the limit of detection is 3.903 μM. However, in vitro biosensing analysis confers that F-MOF (1) is sensable toward the H 2 PO 4 − ion at a trace level in the human lung fibroblast cells and human liver cancer cell line Hep G2.

Homochiral MOF as Chiroptical Sensor for Determination of Absolute Configuration and Enantiomeric Ratio of Chiral Tryptophan

“…Based on these observations, it was expected that the intensity of the ICD signal would continue to increase with electron density of LNNU-1 upon the addition of L-Trp. [76] The increased electron density may result from the π•••π stacking interactions between the indole group of Trp and pyridyl rings of LNNU-1. Therefore, the 1 H NMR experiment confirmed the presence of π•••π stacking interactions.…”

Recent Progress in Adsorptive Removal of Water Pollutants by Metal‐Organic Frameworks

“… Applying hydrophobic groups including fluorine, non‐polar alkyl, or non‐polar methyl groups in the structure of MOFs; [47] Use of hydrophobic and polymeric coatings such as polydimethylsiloxane (PDMS) on MOFs; [48] The establishment of strong bonds between central ions and ligand which may lead to the synthesis of a highly stable MOF structures such as F‐MOF‐1, [49] BUT‐98, [46d] UiO‐66, [50] BUT‐8(Cr), [46a] ZIF‐8, [51] MOF‐801, [52] BUT‐12, BUT‐13, [46g] and etc. ; The use of ligands with higher Pk a than carboxylate‐type ligands in MOF synthesis such as PCN‐601 [46b] and PCN‐602 [46c] alters the stability of MOFs.…”

“…The establishment of strong bonds between central ions and ligand which may lead to the synthesis of a highly stable MOF structures such as F‐MOF‐1, [49] BUT‐98, [46d] UiO‐66, [50] BUT‐8(Cr), [46a] ZIF‐8, [51] MOF‐801, [52] BUT‐12, BUT‐13, [46g] and etc. ;…”

A Reusable Efficient Green Catalyst of 2D Cu-MOF for the Click and Knoevenagel Reaction

“…Metal-organic frameworks (MOFs) are burgeoning targets for their potential applications in gas separation and storage [ 1 , 2 , 3 ], energy research [ 4 , 5 , 6 , 7 , 8 , 9 , 10 ], sensing of ions and molecules [ 11 , 12 , 13 ], bio-imaging [ 14 ], drug delivery [ 15 , 16 ], reusable and recycling sustainable catalyses [ 17 , 18 ], magnetism [ 19 , 20 ], etc. In the last few decades, such materials have received more attention towards development of more flexible catalytic materials owing to their varying symmetric and large pore volume, high surface area, tunable pore size and versatile functionality together with the diversity of metal knots and their redox states, functional groups, and the retention of crystallinity after catalytic reactions.…”