Trace-level measurement of complex combustion effluents and residues using multidimensional gas chromatography–mass spectrometry (MDGC–MS)

Striebich, Richard C.; Rubey, Wayne A.; Klosterman, Joy

doi:10.1016/s0956-053x(02)00024-7

Cited by 13 publications

(14 citation statements)

References 10 publications

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“…To help implementation of this technique in pyrolysis laboratories, only materials available in major pyrolysis laboratories were used. Although a timeof-flight detector was used, similar results can be obtained by using other mass spectrometers [9].…”

Section: Introductionmentioning

confidence: 73%

“…There, the previously focused zone is exposed to the thermal environment of forced flow convection provided by the GC oven and the trapped components are quickly released. On average, it is estimated that the component release time is 30 ms [9].…”

Section: Role Of Modulatormentioning

confidence: 99%

“…When the actuator was extended, the system was in ''trap'' mode and the chemical components within the cold section of the column no longer migrated. As the arm retracted, the trapped section of column was pulled into the heated oven, where the components were released and transported through the secondary column [9]. This trap and release motion is further described in Fig.…”

Section: Role Of Modulatormentioning

confidence: 99%

“…It was determined that the most effective motion of the actuator was a slow extension followed by a rapid retraction. The slow trapping motion created a continual refocusing of the components at the beginning of the trap, preventing the potential breakthrough or migration of the solutes through the cryogenic trap, and lessened the risk of breaking the column [9,17].…”

Section: Role Of Modulatormentioning

confidence: 99%

See 3 more Smart Citations

Multidimensional GC/MS analysis of pyrolytic oils

Fullana

Contreras

Striebich

et al. 2005

Journal of Analytical and Applied Pyrolysis

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Section: Introductionmentioning

confidence: 73%

Section: Role Of Modulatormentioning

confidence: 99%

Section: Role Of Modulatormentioning

confidence: 99%

Section: Role Of Modulatormentioning

confidence: 99%

See 2 more Smart Citations

Multidimensional GC/MS analysis of pyrolytic oils

Fullana

Contreras

Striebich

et al. 2005

Journal of Analytical and Applied Pyrolysis

Self Cite

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“…Extensive reviews on the principles and applications of MDGC and GCxGC have been recently presented by different authors [1][2][3][4][5][6][7].…”

Section: Introductionmentioning

confidence: 99%

Application of Multidimensional (Heart-Cut) Gas Chromatography to the Analysis of Complex Mixtures of Organic Pollutants in Environmental Samples

Alencastro¹,

Grandjean²,

Tarradellas³

2003

Chimia

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This contribution presents some applications developed in our laboratory of multidimensional (heart-cut) gas chromatography (MDGC) applied to the analysis of complex mixtures of pollutants in environmental samples. Practical aspects of this technique as well as qualitative and quantitative examples are discussed. Determination of trace levels of pesticides, polychlorinated biphenyls (PCBs) and polybrominated diphenyl ethers (PBDEs) with MDGC-ECD/ECD and MDGC-ECD/MS in fish, mussels, or sewage sludge is presented.

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Optimization of an online heart‐cutting multidimensional gas chromatography clean‐up step for isotopic ratio mass spectrometry and simultaneous quadrupole mass spectrometry measurements of endogenous anabolic steroid in urine

Casilli¹,

Piper

Oliveira³

et al. 2016

Drug Testing and Analysis

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Measuring carbon isotope ratios (CIRs) of urinary analytes represents a cornerstone of doping control analysis and has been particularly optimized for the detection of the misuse of endogenous steroids. Isotope ratio mass spectrometry (IRMS) of appropriate quality, however, necessitates adequate purities of the investigated steroids, which requires extensive pre-analytical sample clean-up steps due to both the natural presence of the target analytes and the high complexity of the matrix. In order to accelerate the sample preparation and increase the automation of the process, the use of multidimensional gas chromatography (MDGC) prior to IRMS experiments, was investigated. A well-established instrumental configuration based on two independent GC ovens and one heart-cutting device was optimized. The first dimension (1D) separation was obtained by a non-polar column which assured high efficiency and good loading capacity, while the second dimension (2D), based on a mid-polar stationary phase, provided good selectivity. A flame ionization detector monitored the 1D, and the 2D was simultaneously recorded by isotope ratio and quadrupole mass spectrometry. The assembled MDGC set-up was applied for measuring testosterone, 5α- and 5β-androstanediol, androsterone, and etiocholanolone as target compounds and pregnanediol as endogenous reference compound. The urine sample were pretreated by conventional sample preparation steps comprising solid-phase extraction, hydrolysis, and liquid-liquid extraction. The extract obtained was acetylated and different aliquots were injected into the MDGC system. Two high performance liquid chromatography steps, conventionally adopted prior to CIR measurements, were replaced by the MDGC approach. The obtained values were consistent with the conventional ones. Copyright © 2016 John Wiley & Sons, Ltd.

show abstract

Trace-level measurement of complex combustion effluents and residues using multidimensional gas chromatography–mass spectrometry (MDGC–MS)

Cited by 13 publications

References 10 publications

Multidimensional GC/MS analysis of pyrolytic oils

Multidimensional GC/MS analysis of pyrolytic oils

Application of Multidimensional (Heart-Cut) Gas Chromatography to the Analysis of Complex Mixtures of Organic Pollutants in Environmental Samples

Optimization of an online heart‐cutting multidimensional gas chromatography clean‐up step for isotopic ratio mass spectrometry and simultaneous quadrupole mass spectrometry measurements of endogenous anabolic steroid in urine

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