Trace elements in nutrition and health: a deep dive into essentiality and mechanism of their biological roles

Wan, Dan; Yin, Yulong

doi:10.1007/s11427-023-2426-3

Cited by 8 publications

(2 citation statements)

References 14 publications

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“…Many studies have been carried out on the toxicology of cinnabar and its existing form inside the human body. [5] believe that cinnabar may produce methyl mercury when it reacts with methylated substances in the human intestinal tract. Methyl mercury has strong neurotoxicity and is highly liposoluble.…”

Section: Discussion On the Existence Of Mercuric Sulphide In Human Bonementioning

confidence: 99%

Analysis of the Bones from the Han Lingkun Tomb in Xilai Village, Ci County and Preliminary Hypothesis on his Death

2022

JAAS

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In 2013, the tomb of Han Lingkun (923-968 AD) was discovered in the construction process of Ci County, Handan City, Hebei Province. Han Lingkun was a famous general of the Northern Song dynasty (960-1127). Records of his tombstone evidenced that he died from the back disease at the age of 45. Several black bones from an adult were unearthed in the tomb. Scanning Electron Microscope analysis showed that nanoscale cinnabar was detected both on the surface and interior of the black bone. This paper puts forward some possible explanations about the appearance of cinnabar in the black bone: a.Cinnabar entered Han's bones before his death. In this case, cinnabar may be related to the cause of his death.b.Cinnabar was used in the funeral of Han Lingkun.c.The bone was contaminated by the cinnabar from the environment.Amongst these explanations, the first has the most possibility. This research may provide preliminary clues for the death of Han Lingkun, and also devotes to the study of funeral culture in the Song dynasty as well as the toxicology.

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Section: Discussion On the Existence Of Mercuric Sulphide In Human Bonementioning

confidence: 99%

Analysis of the Bones from the Han Lingkun Tomb in Xilai Village, Ci County and Preliminary Hypothesis on his Death

2022

JAAS

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“…Варто додати, що імуномодулючі ефекти багатьох МіБЕ тісно пов'язані з їх безпосередньою участю в реалізації запальних реакцій [3,8]. Нарешті, треба врахувати їх вплив на склад мікробіоти кишечника й участь у виробленні таких корисних вторинних метаболітів, як бактеріоцини та антимікробні пептиди [9]. Отже, надходження в організм дитини біоелементів у недостатній або незбалансованій кількості, безперечно, може бути віднесене до значущих факторів ризику рекурентного перебігу гострих респіраторних інфекцій (ГРІ) [10].…”

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Bioelements and Clustering of Preschool Children Suffering From Recurrent Respiratory Infections

Voloshin,

Marushko,

Savchenko

et al. 2023

Med. Sci. of Ukr.

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Background. Bioelements are essential components for the effective functioning of cellular and humoral immune mechanisms in the human body. There is a direct relationship between the impaired status of many bioelements and increased susceptibility of children, in particular, to respiratory infections. Aim: to identify clusters of preschool children with different frequency of episodes of acute respiratory infections in combination with their bioelemental status. Materials and methods. A total of 41 children (22 boys and 19 girls) aged 1-6 years, undergoing inpatient treatment on acute respiratory infection, were involved in the clinical study. The integral indicator of acute respiratory infections recurrence, i.e. the infectious index, was taken into account for each patient. The hair of 30 children was tested for the content of 13 bioelements – Zn, Fe, Cu, Se, Mn, Cr, Co, Br Ni, Ca, K, S, and Cl. Besides, the serum concentration of Mg was examined in 40 children. The statistical processing of the obtained digital material was performed with IBM SPSS Statistics 28 licensed software. A combination of factor and cluster hierarchical analysis was used. Results. The particular micro- and macroelements demonstrate a statistically significant direct or inverse relationship. The most closely correlated are the following pair combinations: S*Co (ρ=0.645; p<0.001; 95% CI [0.362-0.820]); K*Mn/Cr (ρ=-0.547; p=0.002; 95% CI [-0.763–(-0.222)]) and Ca*Mn (ρ=0.500; p=0.005; 95% CI [0.160-0.734]). The conducted factor analysis shows the presence of 5 new combinations including all 14 studied bioelements. The most influential bioelements in these combinations are S, Cu, Zn, Mg, and Fe. The cluster distribution of the examined children according to their bioelemental status has no clear relationship with the infectious index values. Conclusion. The information on the interdependence between the studied bioelements can be used in planning of further scientific studies of immune mechanisms. The data obtained clarify the requirements for the most effective application of factor and cluster analysis in the study of risk predictors of recurrent respiratory infections in pediatric practice.

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AP-1 and SP1 trans-activate the expression of hepatic CYP1A1 and CYP2A6 in the bioactivation of AFB1 in chicken

Deng,

Yang,

Feng

et al. 2024

Sci. China Life Sci.

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Trace elements in nutrition and health: a deep dive into essentiality and mechanism of their biological roles

Cited by 8 publications

References 14 publications

Analysis of the Bones from the Han Lingkun Tomb in Xilai Village, Ci County and Preliminary Hypothesis on his Death

Analysis of the Bones from the Han Lingkun Tomb in Xilai Village, Ci County and Preliminary Hypothesis on his Death

Bioelements and Clustering of Preschool Children Suffering From Recurrent Respiratory Infections

AP-1 and SP1 trans-activate the expression of hepatic CYP1A1 and CYP2A6 in the bioactivation of AFB1 in chicken

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