Trace elements content and hormonal profiles in women with androgenetic alopecia

Skalnaya, Margarita G.; Tkachev, Vladislav P.

doi:10.1016/j.jtemb.2010.10.006

Cited by 21 publications

(8 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…showed a regional variation in scalp hair zinc level with lower zinc content in the hair of frontal area in comparison to the occipital area in women with AGA. [20] Other study by Kil et al . on healthy controls and patients with different types of alopecia including AGA, they noticed that serum zinc concentration in all patients was significantly lower than the control group.…”

Section: Discussionmentioning

confidence: 99%

Estimation of zinc and iron levels in the serum and hair of women with androgenetic alopecia: Case–control study

Dhaher

Yacoub

Jacob³

2018

Indian J Dermatol

View full text Add to dashboard Cite

Background:Although female androgenetic alopecia (FAGA) occurs in genetically susceptible women, some trace elements may play an important role.Aim of the Study:This study aimed to evaluate serum and hair zinc and iron levels in patients with FAGA and to compare the findings with normal controls.Patients and Methods:A case–control study that was conducted at Dermatology Clinic in Basra General Hospital, Basra, Iraq. The participants were divided into two groups: The first group consisted of 27 women with FAGA and the second was age-matched 28 healthy women control group. The serum and hair zinc and iron assays were done for all participants.Results:Both hair and serum zinc levels in FAGA group were significantly lower than that in the control (103.4±25.5 ppm vs. 143.5±33.1 ppm for hair and 65.6±14.2 μg/dl vs. 128.4±41.4 μg/dl for serum). Hair iron level in FAGA was significantly lower than in control (17.9±3.8 ppm vs. 26.9±7.4 ppm, P>0.05). Serum iron level in FAGA group was lower than in the control, but it was not significant statistically (88.9±22.3 μg/dl vs. 100.9±18.9 μg/dl). Except for the hair iron, there was no significant correlation between zinc and iron concentrations in hair and serum with severity of alopecia.Conclusions:Zinc and iron levels in serum and hair were lower in FAGA compared to that of normal individuals indicating that trace elements might play an important role in the etiopathogenesis of FAGA.

show abstract

Section: Discussionmentioning

confidence: 99%

Estimation of zinc and iron levels in the serum and hair of women with androgenetic alopecia: Case–control study

Dhaher

Yacoub

Jacob³

2018

Indian J Dermatol

View full text Add to dashboard Cite

show abstract

“…Several previous studies have associated androgenetic alopecia with metabolic syndrome 38 or insulin resistance presence 39 . Also, low zinc serum levels 40 have been found to be related with hair loss. It could be suggested that the parietal area may be sensitive to metabolic disturbances.…”

Section: Discussionmentioning

confidence: 99%

Isolation and Quantification of Glycosaminoglycans from Human Hair Shaft

2016

View full text Add to dashboard Cite

BackgroundThere is evidence that glycosaminoglycans (GAGs) are present in the hair shaft within the follicle but there are no studies regarding GAGs isolation and measurement in the human hair shaft over the scalp surface, it means, in the free hair shaft.ObjectiveThe purpose of our research was to isolate and measure the total GAGs from human free hair shaft.MethodsSeventy-five healthy individuals participated in the study, 58 adults, men and women over the age of 50 and 17 children (aged 4~9). GAGs in hair samples, received from the parietal and the occipital areas, were isolated with 4 M guanidine HCl and measured by the uronic acid-carbazole reaction assay.ResultsGAGs concentration was significantly higher in the occipital area than in the parietal area, in all study groups. GAG levels from both areas were significantly higher in children than in adults. GAG levels were not associated with gender, hair color or type.ConclusionWe report the presence of GAGs in the human free hair shaft and the correlation of hair GAG levels with the scalp area and participants' age.

show abstract

“…Zinc acts as a 5-α reductase inhibitor [11]. Recently intradermal injection of copper has been suggested to be beneficial in AGA most likely by balancing the steroid-converting enzyme activity, enhancing the anagen phase of hair cycle, simultaneous transition to the telogen phase, and stimulation of the proliferation of dermal papilla cells [19]. Finasteride is an inhibitor of 5-α reductase enzyme and selectively interfere with the androgen activity on skin [18].…”

Section: Solutions and Substancesmentioning

confidence: 99%

Cosmetic Procedures in the Treatment of Alopecia

Kartal¹,

Altunel²,

Gençler³

2017

Hair and Scalp Disorders

View full text Add to dashboard Cite

Alopecia has a significant negative impact on the quality of life. Unfortunately, there is no satisfactory cure for most types of alopecia. Alopecia is divided into cicatricial and noncicatricial types. Androgenetic alopecia, alopecia areata, and telogen effluvium are common forms of noncicatricial alopecias. In order to treat or improve the appearance, various procedures that are being applied for different types of alopecia including mesotherapy, microneedling, platelet-rich plasma, low-level light therapy, and stem-cell therapy with variable outcomes are reviewed in this chapter.

show abstract

Trace elements content and hormonal profiles in women with androgenetic alopecia

Cited by 21 publications

References 11 publications

Estimation of zinc and iron levels in the serum and hair of women with androgenetic alopecia: Case–control study

Estimation of zinc and iron levels in the serum and hair of women with androgenetic alopecia: Case–control study

Isolation and Quantification of Glycosaminoglycans from Human Hair Shaft

Cosmetic Procedures in the Treatment of Alopecia

Contact Info

Product

Resources

About