Trace element concentrations, risks and their correlation with metallothionein genes polymorphism: A case study of narrow-ridged finless porpoises (Neophocaena asiaeorientalis) in the East China Sea

Jun, Liu; Chen, Bingyao; Jefferson, Thomas A.; Wang, Hui; Yang, Guang

doi:10.1016/j.scitotenv.2016.09.062

Cited by 10 publications

(2 citation statements)

References 46 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Zinc (Zn) and mercury (Hg) were selected to place these soluble organic contaminants in context to the risks from these well known metal contaminants. These two metals are frequently detected in the environment and are potentially hazardous to the environmental organisms (Delgado et al, 1993;Li et al, 2014;Liu et al, 2017).…”

Section: Study Area Chemical Selection and The Collection Of Monitormentioning

confidence: 99%

The relative risk and its distribution of endocrine disrupting chemicals, pharmaceuticals and personal care products to freshwater organisms in the Bohai Rim, China

Zhang

Shi

Lü

et al. 2017

Science of The Total Environment

View full text Add to dashboard Cite

In this study, the risks to aquatic organisms posed by 12 commonly detected pharmaceuticals and personal care products (PPCPs) and endocrine disrupting chemicals (EDCs) that are extensively used in Bohai coastal region of China were examined. These were linear alkylbenzene sulfonate (LAS), nonylphenol (NP), diethylhexyl phthalate (DEHP), norfloxacin (NOR), sulfamethoxazole (SMX), erythromycin (ERY), bisphenol A (BPA), ofloxacin (OFL), carbamazepine (CBZ), naproxen (NPX), atenolol (ATL) and metoprolol (MET). Their relative risk was ranked based on the proximity between the medians of the reported effect concentrations and measured river or lake water concentrations. The surfactants (LAS) and endocrine disrupting chemicals NP (a breakdown product of the surfactant nonylphenol polyethoxylate) and DEHP (a plasticizer) were identified as posing the greatest risk from this range of chemicals. LAS had a hundred-fold higher risk than any of the pharmaceuticals. The highest risk ranked pharmaceuticals were all antibiotics. Zinc (Zn) and mercury (Hg) were added to the comparison as representative heavy metals. Zn posed a risk higher than all the organics. The risk posed by Hg was less than the surfactants but greater than the selected pharmaceuticals. Whereas LAS and DEHP could cause harmful effects to all the wildlife groups, NP and BPA posed the greatest risk to fish. Antibiotics showed the highest risk to algae. Spatial and temporal distributions of PPCPs and EDCs were conducted for risk identification, source analysis and seasonal change exploration. Municipal sewage effluent linked to urban areas was considered to be the major source of pharmaceuticals. With regard to seasonal influence the risk posed by LAS to the aquatic organisms was significantly affected by wet and dry seasonal change. The dilution effects were the common feature of LAS and ERY risks. The difference in LAS and ERY risk patterns along the rivers was mainly affected by the elimination process.

show abstract

Section: Study Area Chemical Selection and The Collection Of Monitormentioning

confidence: 99%

The relative risk and its distribution of endocrine disrupting chemicals, pharmaceuticals and personal care products to freshwater organisms in the Bohai Rim, China

Zhang

Shi

Lü

et al. 2017

Science of The Total Environment

View full text Add to dashboard Cite

show abstract

“…Their molecular approach can be explained by the fact that only a few nucleotide sequences of Mts have been well characterized from the genomes and transcriptomes of cetaceans yet. Liu et al [ 57 ] published an innovative study focused on the metallothionein genes. They characterized the Mt2 and Mt4 alleles associated with metal levels in dolphin tissues (kidney, liver, and muscle).…”

Section: Introductionmentioning

confidence: 99%

Assessment of Knowledge on Metal Trace Element Concentrations and Metallothionein Biomarkers in Cetaceans

Leignel,

Pillot,

Gerpe

et al. 2023

Toxics

View full text Add to dashboard Cite

Cetaceans are recognized as bioindicators of pollution in oceans. These marine mammals are final trophic chain consumers and easily accumulate pollutants. For example, metals are abundant in oceans and commonly found in the cetacean tissues. Metallothioneins (MTs) are small non-enzyme proteins involved in metal cell regulation and are essential in many cellular processes (cell proliferation, redox balance, etc.). Thus, the MT levels and the concentrations of metals in cetacean tissue are positively correlated. Four types of metallothioneins (MT1, 2, 3, and 4) are found in mammals, which may have a distinct expression in tissues. Surprisingly, only a few genes or mRNA-encoding metallothioneins are characterized in cetaceans; molecular studies are focused on MT quantification, using biochemical methods. Thus, we characterized, in transcriptomic and genomic data, more than 200 complete sequences of metallothioneins (mt1, 2, 3, and 4) in cetacean species to study their structural variability and to propose to the scientific research community Mt genes dataset to develop in future molecular approaches which will study the four types of metallothioneins in diversified organs (brain, gonad, intestine, kidney, stomach, etc.).

show abstract

Biomonitoring metals and metalloids in wild mammals: invasive versus non-invasive sampling

Baptista

Seixas

Gonzalo-Orden

et al. 2022

Environ Sci Pollut Res

View full text Add to dashboard Cite

Trace element concentrations, risks and their correlation with metallothionein genes polymorphism: A case study of narrow-ridged finless porpoises (Neophocaena asiaeorientalis) in the East China Sea

Cited by 10 publications

References 46 publications

The relative risk and its distribution of endocrine disrupting chemicals, pharmaceuticals and personal care products to freshwater organisms in the Bohai Rim, China

The relative risk and its distribution of endocrine disrupting chemicals, pharmaceuticals and personal care products to freshwater organisms in the Bohai Rim, China

Assessment of Knowledge on Metal Trace Element Concentrations and Metallothionein Biomarkers in Cetaceans

Biomonitoring metals and metalloids in wild mammals: invasive versus non-invasive sampling

Contact Info

Product

Resources

About