Trace detection of endogenous human volatile organic compounds for search, rescue and emergency applications

Agapiou, Agapios; Amann, Anton; Mochalski, Paweł; Statheropoulos, M.; Thomas, C. L. Paul

doi:10.1016/j.trac.2014.11.018

Cited by 73 publications

(46 citation statements)

References 128 publications

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“…Currently, rescue teams locate victims using mainly searching dogs, which exhibit, however, a number of limitations. A number of recent studies suggested that the chemical analysis of air at the disaster site, aimed at the victims' scent, could considerably improve the victims' detection and, thereby, the effectiveness of SAR operations [2,4,6,8,25,[27][28][29][30]39]. Nevertheless, the application of chemical analysis during urban SAR operations, demands the proper recognition of all confounders, which could affect its results.…”

Section: Discussionmentioning

confidence: 99%

Analysis of volatile organic compounds released from the decay of surrogate human models simulating victims of collapsed buildings by thermal desorption–comprehensive two-dimensional gas chromatography–time of flight mass spectrometry

Agapiou

Zorba

Mikedi

et al. 2015

Analytica Chimica Acta

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Section: Discussionmentioning

confidence: 99%

Analysis of volatile organic compounds released from the decay of surrogate human models simulating victims of collapsed buildings by thermal desorption–comprehensive two-dimensional gas chromatography–time of flight mass spectrometry

Agapiou

Zorba

Mikedi

et al. 2015

Analytica Chimica Acta

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“…Compounds in exhaled breath gas are generally classified as [3]:Inorganic compounds, such as nitric oxide, oxygen, and carbon dioxide [18]. …”

Section: Introductionmentioning

confidence: 99%

“…In the context of the diagnosis of human diseases, a number of volatile biomarkers in exhaled breath have been reported [17, 18, 20–24]. It is essential to determine such biomarkers in order to monitor metabolic or any pathologic processes in the body.…”

Section: Introductionmentioning

confidence: 99%

Significance of Exhaled Breath Test in Clinical Diagnosis: A Special Focus on the Detection of Diabetes Mellitus

2016

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Analysis of volatile organic compounds (VOCs) emanating from human exhaled breath can provide deep insight into the status of various biochemical processes in the human body. VOCs can serve as potential biomarkers of physiological and pathophysiological conditions related to several diseases. Breath VOC analysis, a noninvasive and quick biomonitoring approach, also has potential for the early detection and progress monitoring of several diseases. This paper gives an overview of the major VOCs present in human exhaled breath, possible biochemical pathways of breath VOC generation, diagnostic importance of their analysis, and analytical techniques used in the breath test. Breath analysis relating to diabetes mellitus and its characteristic breath biomarkers is focused on. Finally, some challenges and limitations of the breath test are discussed.

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“…A number of compounds are considered biomarkers that generates information of great importance on human status [15][16][17][18][19][20]. The development of different methods allow the detection of volatiles present in the breath at low concentrations.…”

Section: Introductionmentioning

confidence: 99%

Applications of Near Infrared Photoacoustic Spectroscopy for Analysis of Human Respiration: A Review

et al. 2020

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In this review, applications of near-infrared photoacoustic spectroscopy are presented as an opportunity to evaluate human respiration because the measurement of breath is fast, intact and simple to implement. Recently, analytical methods for measuring biomarkers in exhaled air have been extensively developed. With laser-based photoacoustic spectroscopy, volatile organic compounds can be identified with high sensitivity, at a high rate, and with very good selectivity. The literature review has shown the applicability of near-infrared photoacoustic spectroscopy to one of the problems of the real world, i.e., human health. In addition, the review will consider and explore different breath sampling methods for human respiration analysis.

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Trace detection of endogenous human volatile organic compounds for search, rescue and emergency applications

Cited by 73 publications

References 128 publications

Analysis of volatile organic compounds released from the decay of surrogate human models simulating victims of collapsed buildings by thermal desorption–comprehensive two-dimensional gas chromatography–time of flight mass spectrometry

Analysis of volatile organic compounds released from the decay of surrogate human models simulating victims of collapsed buildings by thermal desorption–comprehensive two-dimensional gas chromatography–time of flight mass spectrometry

Significance of Exhaled Breath Test in Clinical Diagnosis: A Special Focus on the Detection of Diabetes Mellitus

Applications of Near Infrared Photoacoustic Spectroscopy for Analysis of Human Respiration: A Review

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