Trabecular coating on curved alumina substrates using a novel bioactive and strong glass-ceramic

Baino, Francesco; Vitale-Brovarone, C.

doi:10.1515/bglass-2015-0003

Cited by 9 publications

(7 citation statements)

References 37 publications

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“…2a) [53,54], while the outer trabecular coating was successfully produced by properly adapting the sponge replica method to the 3D radial geometry of the prosthesis (Figs. 2b and 2c) [55][56][57]. In these studies, the issue of estimating reliably the adhesion strength of the bioactive coating to the curved substrate was also tackled: specifically, the recommendations of the relevant ASTM standard dealing with pull-out tests on flat samples [58] were properly adapted for a "nearly-flat" geometry and appropriate testing tools were manufactured for this purpose [53].…”

Section: Orthopaedic and Dental Implantsmentioning

confidence: 99%

Glass-based coatings on biomedical implants: a state-of-the-art review

Baino¹,

Verné²

2017

Biomedical Glasses

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Bioactive glasses, invented by Prof. Larry L. Hench in the late 1960s, have revolutionized the field of biomaterials as they were shown to tightly bond to both hard and soft living tissues and to stimulate cells towards a path of regeneration and self-repair. However, due to their relatively poor mechanical properties (brittleness, low bending strength and fracture toughness), they are generally unsuitable for load-bearing applications. On the other hand, bioactive glasses have been successfully applied as coatings on the surface of stronger/tougher substrates to combine adequate mechanical properties with high bioactivity and, in some cases, additional extrafunctionalities (e.g. antibacterial properties, drug release). After giving a short overview of the main issues concerning the fabrication of glass coatings, this review provides a state-of-the-art picture in the field and specifically discusses the development of bioactive and hierarchical coatings on 3D porous scaffolds, joint prostheses, metallic substrates (e.g. wires or nails) for orthopedic fixation, polymeric meshes and sutures for wound healing, ocular implants and percutaneous devices.

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Section: Orthopaedic and Dental Implantsmentioning

confidence: 99%

Glass-based coatings on biomedical implants: a state-of-the-art review

Baino¹,

Verné²

2017

Biomedical Glasses

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“…1). Previous studies demonstrated the feasibility of this device in a flat geometry [26,27] and in a simplified curved configuration [28][29][30]; the challenge presented in this work is to develop a processing schedule to produce a real, complete prototype such as the one depicted schematically in Fig. 1, which also was the main objective of the EC-funded project MATCh.…”

Section: Introductionmentioning

confidence: 99%

Novel full-ceramic monoblock acetabular cup with a bioactive trabecular coating: design, fabrication and characterization

Baino

Minguella-Canela

Kirk

et al. 2016

Ceramics International

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Over the last 25 years, the philosophy behind an optimal fixation of orthopaedic implants to hard tissues progressively evolved towards "bone-conservative" solutions in order to minimize bone resection/loss and maximize tissue-implant integration. Hence, the researchers' attention moved from "traditional" fixation of the prosthesis to host bone by using screws or acrylic cement to new strategies based on physico-chemical bonding and surface modification of the implant. This research work explores the feasibility of a novel bioceramic monoblock acetabular cup for hip joint prosthesis that can be fixed to the patient's bone by means of a bone-like trabecular coating able to promote implant osteointegration. Sponge replica method was properly adapted and optimized to produce hemispherical foam-like bioactive glass-ceramic coatings that were joined to Al 2 O 3 /ZrO 2 composite cups by the interposition of a glass-ceramic interlayer. Morphological analyses by scanning electron microscopy (SEM) and micro-computed tomography revealed the good quality of joining at the different interfaces. Preliminary investigation of the mechanical properties was carried out to evaluate the suitability of the device for biomedical use. In vitro bioactive behaviour was assessed by immersion studies in simulated body fluid and evaluating the apatite formation on the struts of the trabecular coating. The concepts and findings reported in the present work can have a significant impact in the field of implantable devices, suggesting a valuable alternative to currently-applied but often suboptimal techniques for bone-prosthesis fixation.

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“…This composition was then discarded with respect to such applications, as the high content of SiO 2 and the significant presence of Al 2 O 3 resulted in an almost inert behavior with almost no apatite-forming capability in contact with biological fluids, thereby preventing the formation of a tight bond to bone. However, the material was found highly suitable to produce porous orbital implants [20], which must elicit minimal or no reactions in contact with ocular tissues [21], and multilayer coatings onto ceramic implants [22].…”

Section: Resultsmentioning

confidence: 99%

Quantifying the Adhesion of Silicate Glass–Ceramic Coatings onto Alumina for Biomedical Applications

Baino

2019

Materials

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Deposition of bioactive glass or ceramic coatings on the outer surface of joint prostheses is a valuable strategy to improve the osteointegration of implants and is typically produced using biocompatible but non-bioactive materials. Quantifying the coating–implant adhesion in terms of bonding strength and toughness is still a challenge to biomaterials scientists. In this work, wollastonite (CaSiO3)-containing glass–ceramic coatings were manufactured on alumina tiles by sinter-crystallization of SiO2–CaO–Na2O–Al2O3 glass powder, and it was observed that the bonding strength decreased from 34 to 10 MPa as the coating thickness increased from 50 to 300 µm. From the viewpoint of bonding strength, the coatings with thickness below 250 µm were considered suitable for biomedical applications according to current international standards. A mechanical model based on quantized fracture mechanics allowed estimating the fracture toughness of the coating on the basis of the experimental data from tensile tests. The critical strain energy release rate was also found to decrease from 1.86 to 0.10 J/m2 with the increase of coating thickness, which therefore plays a key role in determining the mechanical properties of the materials.

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Trabecular coating on curved alumina substrates using a novel bioactive and strong glass-ceramic

Cited by 9 publications

References 37 publications

Glass-based coatings on biomedical implants: a state-of-the-art review

Glass-based coatings on biomedical implants: a state-of-the-art review

Novel full-ceramic monoblock acetabular cup with a bioactive trabecular coating: design, fabrication and characterization

Quantifying the Adhesion of Silicate Glass–Ceramic Coatings onto Alumina for Biomedical Applications

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