Trabecular Bone Score in obese, overweight and normal-weight young men

Ayoub, Marie-Louise; Khoury, Georges; Zakhem, Eddy; Khoury, César El; Cortet, Bernard; Hage, Rawad El

doi:10.1016/j.scispo.2016.08.004

Cited by 6 publications

(2 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Overall random effects model showed a lower TBS score among obese subject by 0,07 (95% CI 0,05 -0,09) points. The effects were consistent across studies, except in Ayoub et al (2017) studies. The overall heterogeneity was moderate (I 2 = 37%, p = 0,17).…”

Section: Association Of Bmi and Tbssupporting

confidence: 52%

Body mass index inversely associated with bone microarchitecture quality: a systematic review and meta-analysis

Kusuman

Wiryadana

Setiawan

et al. 2022

IJBS

View full text Add to dashboard Cite

Introduction: The rising prevalence of obesity forces the orthopedist to consider it in fracture risk assessment. Multiple studies have consistently demonstrated that people with obesity have increased bone mineral density (BMD). Although it appears other factors in bone strength may influence the fracture risk, including bone microarchitecture, which recently can be measured by trabecular bone score (TBS). The complex associations between TBS and BMI remain unclear, and some studies show inconsistent findings. This systematic review and meta-analysis aimed to understand whether increased BMI is associated with lower TBS by indirectly pooling all the available evidence from the published literature. Methods: A literature search was carried out using PubMed, Cochrane Library, Google Scholar and other popular journal databases using the terms "trabecular bone score", "body mass index" and the possible synonyms. We extracted the total sample, mean and standard deviation of TBS for patients within each BMI category from the selected literature. A meta-analysis was conducted using a random-effects model and inverse variant methods to synthesize the pooled effect size (mean difference) for each gender subgroup. Results: After an initial search and screening of 2399 studies, seven reports published between 2016-2019 were included (five cross-sectional, one cohort, and one randomized clinical trial). These include 2872 samples which were mostly women (2286). One thousand thirty-one samples were with normal BMI, 1124 samples were with overweight BMI, and 717 samples were with obesity. The included studies varied by age group and gender. The between-study heterogeneity with I2 index ranging 0%-76% studies in man showed higher heterogeneity. Compared with normal individuals, those with overweight and obesity had lower TBS with a mean difference of -0.02 (95% CI -0.03 to -0.01) and -0.07 (95% CI, -0.09 to -0.05), respectively. The differences were consistent across gender, although larger differences were found in men. Conclusion: Individuals with higher BMI have a lower TBS than individuals with normal BMI in a stepwise manner. It suggests that the inclusion of TBS can improve the assessment of fracture risk in obese individuals.

show abstract

Section: Association Of Bmi and Tbssupporting

confidence: 52%

Body mass index inversely associated with bone microarchitecture quality: a systematic review and meta-analysis

Kusuman

Wiryadana

Setiawan

et al. 2022

IJBS

View full text Add to dashboard Cite

show abstract

“…In the absence of HF, high BMI may interfere with the accuracy of TBS. [27][28][29][30] However, to our knowledge, no previous studies have evaluated the correlation between TBS and BMI in individuals with HF. Therefore, despite the small number of patients undergoing this method, our study demonstrated TBS to be an important tool in assessing bone health in individuals with HF without major interference that may be attributable to BMI.…”

Section: Discussionmentioning

confidence: 99%

Bone Mineral Density, Trabecular Bone Score and Fractures in Patients Hospitalized for Heart Failure

Oliveira,

de Figueiredo Martins Siqueira,

de Macedo Gadêlha

et al. 2023

J Bone Metab

View full text Add to dashboard Cite

Background: This study aimed to evaluate the bone mineral density (BMD), trabecular bone score (TBS), and fracture history of middle-aged patients hospitalized for heart failure (HF), as well as analyze the association of these factors with cardiometabolic parameters and muscle strength.Methods: A cross-sectional study with patients aged 40 to 64 years hospitalized for HF was performed. Dual energy X-ray absorptiometry was performed to obtain BMD and TBS. Fracture history, handgrip strength (HGS), and clinical and laboratory cardiometabolic parameters of the patients were evaluated.Results: Altogether, 109 patients were evaluated (female 50.5%). Medians and interquartile ranges for age and length of hospital stay were 58.0 (53.0–61.0) years and 20.0 (11.0–32.0) days, respectively. Osteoporosis was observed in 15.6% of the patients, low TBS was observed in 22.8%, and 6 patients had a history of fragile fracture. No differences between the sexes regarding BMD (p=0.335) or TBS (p=0.736) classifications were observed. No association was observed between low BMD and HF classification (p>0.05) regarding the ejection fraction, ischemic etiology, or New York Heart Association Functional Classification. However, there was a significant association between high serum parathyroid hormone (PTH) and the presence of osteoporosis (62.5 [37.2–119.0] pg/mL vs. 34.2 [25.0–54.1] pg/mL; p=0.016). There was a negative correlation between serum PTH and TBS (r=−0.329, p=0.038) and a higher frequency of reduced HGS in patients with low TBS (92.3% vs. 50.0%; p=0.009).Conclusions: We found relevant frequencies of osteoporosis and bone microarchitecture degradation in middle-aged patients with HF, which were related to high serum PTH concentrations.

show abstract

Bone characteristics and metabolic phenotypes of obesity in an Iranian Elderly population: Bushehr Elderly Health Program (BEHP)

et al. 2021

View full text Add to dashboard Cite

Trabecular Bone Score in obese, overweight and normal-weight young men

Cited by 6 publications

References 28 publications

Body mass index inversely associated with bone microarchitecture quality: a systematic review and meta-analysis

Body mass index inversely associated with bone microarchitecture quality: a systematic review and meta-analysis

Bone Mineral Density, Trabecular Bone Score and Fractures in Patients Hospitalized for Heart Failure

Bone characteristics and metabolic phenotypes of obesity in an Iranian Elderly population: Bushehr Elderly Health Program (BEHP)

Contact Info

Product

Resources

About