TPF induction chemotherapy versus PF adjuvant chemotherapy plus concurrent chemoradiotherapy for locally advanced nasopharyngeal carcinoma: a multicenter, randomized controlled phase III trial
Feng Jin,
Qianyong He,
Yuanyuan Li
et al.
Abstract:The efficacy and safety of TPF-induced chemotherapy(IC) combined with concurrent chemoradiotherapy(CCRT) compared to CCRT and sequential PF-adjuvant chemotherapy(AC) lack randomized controlled clinical trials for evaluation, so the comparative efficacy and safety between the two approaches remain unclear. In this phase III trial(NCT03574324), 266 patients were enrolled and randomly assigned to either the IC group or the AC group. The IC group received TPF followed by CCRT, while the AC group received CCRT foll… Show more
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