Tp-e/QT ratio and QT dispersion with respect to blood pressure dipping pattern in prehypertension

Tanındı, Aslı; Alhan, Aslıhan; Töre, Hasan Fehmi

doi:10.1097/mbp.0000000000000090

Cited by 6 publications

(10 citation statements)

References 20 publications

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“…In our study, heart rate was significantly different among dippers, non-dippers and reverse-dippers in elderly patients with essential hypertension. Moreover, heart rate was lowest in revere-dippers and highest in non-dippers in elderly hypertensive patients, which was inconsistent with previous studies [9,28]. The reverse dipping status is related to the greatest sympathetic activation, which may result in higher heart rate [25].…”

Section: Discussioncontrasting

confidence: 67%

“…However, Karaagac et al demonstrated that QTc interval was similar between dippers and non-dippers in patients with metabolic syndrome [8]. Moreover, there was no significant difference among dippers, non-dippers and reverse-dippers in patients with prehypertension in another study [9]. Based on the previous studies, the relationship between QTc and circadian variation of blood pressure remains controversial.…”

Section: Discussionmentioning

confidence: 97%

“…With the increase of 60ms in QTc interval compared to the baseline value, the TdP risk increases [22]. There have been several studies investigating the relationship between QTc interval and the nocturnal drop of blood pressure [8][9][10]. Passino et al demonstrated that non-dippers had longer QTc intervals than dippers in hypertensive patients.…”

Section: Discussionmentioning

confidence: 99%

“…There have been several studies investigating the association between electrocardiographic evaluation [eg: heart rate , frontal QRS-T angle, QTc interval, Tpeak to Tend interval and left ventricular hypertrophy (LVH)] and the circadian variation of BP [8][9][10]. However, the effect of circadian variation of BP on electrocardiographic evaluation remains controversial.…”

Section: Introductionmentioning

confidence: 99%

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QTc interval predicts disturbed circadian blood pressure variation

et al. 2020

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AbstractBackgroundThe relationship between electrocardiographic evaluation and circadian blood pressure (BP) variation in young and middle-aged hypertensive patients remains unknown.MethodsA total of 171 hypertensive patients were included in the study. First, patients were divided into a young and middle-aged group and an elderly group. The two groups were then separately classified into three subgroups on the basis of circadian variation of BP as dippers, non-dippers and reverse-dippers. The electrocardiographic evaluation was calculated from 12-lead electrocardiography (ECG).ResultsQTc intervals were shortest in the dippers and longest in the reverse-dippers in the young and middle-aged group (QTc dipper: 416.53±18.37ms; non-dipper: 438.30±29.71ms; reverse-dipper: 444.93±25.47ms; for dipper vs non-dipper, and dipper vs reverse-dipper P<0.05). QTc interval was found to be an independent risk factor for the non-dipper BP pattern (Odds ratio 1.049; 95% CI 1.01-1.089; P=0.012) and reverse-dipper BP pattern (Odds ratio 1.051; 95% CI 1.007-1.098; P=0.023) in young and middle-aged hypertensive patients. No significant differences in other ECG parameters were found among the three subgroups in the young and middle-aged group.ConclusionOur study suggested that QTc interval might serve as a risk factor for non-dipper BP pattern and reverse-dipper BP pattern in young and middle-aged hypertensive patients.

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Section: Discussioncontrasting

confidence: 67%

Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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QTc interval predicts disturbed circadian blood pressure variation

et al. 2020

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“…Previous studies reported that deteriorated circadian blood pressure variability in prehypertensive patients may be associated with repolarization abnormalities detected by ECG. 15 However, as a marker of depolarization abnormality, the importance of fQRS in prehypertensive patients is not clear. fQRS is a sign of inhomogenous ventricular conduction caused by myocardial scar, ischemia, or fibrosis.…”

Section: Discussionmentioning

confidence: 99%

Association Between Non-Dipping and Fragmented QRS Complexes in Prehypertensive Patients

Eyuboglu¹,

Akdeniz²

2018

Arquivos Brasileiros De Cardiologia

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BackgroundFragmented QRS (fQRS) is a sign of adverse cardiovascular events in various cardiovascular diseases. It is also associated with increased blood pressure and non-dipping in hypertensive patients. However, no study has investigated the importance of fQRS in prehypertensive patients.ObjectivesThe aim of our study is to investigate the relationship between fQRS and non-dipper status in prehypertensive patients.MethodsTwo hundred and sixteen eligible, newly diagnosed prehypertensive patients who underwent 24-hour ambulatory blood pressure monitoring (ABPM) for further evaluation of blood pressure between June 2015 and July 2016 were included into the study. Patients were divided into three groups according to ABPM results: normotensives, dipper prehypertensives, and non-dipper prehypertensives. Groups were compared regarding presence of fQRS on electrocardiography. Additionally, multinomial logistic regression analysis was used to determine the relationship between fQRS and blood pressure pattern in prehypertensive patients.ResultsAccording to ABPM recordings, 61 patients had normotensive blood pressure pattern (systolic blood pressure < 120 mmHg and diastolic blood pressure < 80 mmHg). Of the remaining 155 prehypertensive patients, 83 were dippers and 72 were non-dippers. Non-dipper prehypertensives had a significantly higher frequency of fQRS compared to normotensives (p = 0.048). Furthermore, multinomial logistic regression analysis revealed that fQRS is an independent predictor of non-dipping blood pressure pattern in prehypertensive patients (p = 0.017, OR: 4.071, 95% CI: 1.281-12.936).ConclusionsWe found that fQRS is a predictor of non-dipping in prehypertensives. As a marker of fibrosis and higher fibrotic burden within myocardium, fQRS may be useful in identifying high-risk prehypertensive patients before the development of hypertension.

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Current evidence suggests that estimating blood pressure from convenient ECG waveforms alone is not viable

Landry,

Mukkamala

2023

Journal of Electrocardiology

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Tp-e/QT ratio and QT dispersion with respect to blood pressure dipping pattern in prehypertension

Abstract: Tp-e, Tp-e/QT, and cQTd are increased in prehypertensives compared with normotensives. Tp-e and Tp-e/QT are associated with the dipping status in prehypertensives.

Cited by 6 publications

References 20 publications

QTc interval predicts disturbed circadian blood pressure variation

QTc interval predicts disturbed circadian blood pressure variation

Association Between Non-Dipping and Fragmented QRS Complexes in Prehypertensive Patients

Current evidence suggests that estimating blood pressure from convenient ECG waveforms alone is not viable

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