Toxoplasmosis cerebral congénita e infección por el virus del Zika y del chikunguña: reporte de un caso

Gunturiz, María Luz; Cortés, Liliana Jazmín; Cuevas, Ester Liliana; Chaparro, Pablo; Ospina, Martha

doi:10.7705/biomedica.v38i0.3652

Cited by 6 publications

(2 citation statements)

References 46 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, co-infections in children do not show increased pathology. Following the 2015 CHIKV and Zika outbreaks in Colombia, a 25-week pregnant mother was diagnosed with Toxoplasma gondii , Zika virus, and CHIKV-WH in her amniotic fluid [142]. Severe neurological and physical deformities were identified resulting in early termination of pregnancy [142].…”

Section: Consequences Of Co-infectionmentioning

confidence: 99%

“…Following the 2015 CHIKV and Zika outbreaks in Colombia, a 25-week pregnant mother was diagnosed with Toxoplasma gondii , Zika virus, and CHIKV-WH in her amniotic fluid [142]. Severe neurological and physical deformities were identified resulting in early termination of pregnancy [142]. In March the following year, a female in her second trimester was diagnosed by RT-PCR with a CHIKV-WH-Zika virus co-infection following an abnormal sonogram, which indicated no fetal heartbeat [143].…”

Section: Consequences Of Co-infectionmentioning

confidence: 99%

See 1 more Smart Citation

Chikungunya in Infants and Children: Is Pathogenesis Increasing?

Barr

Vaidhyanathan

2019

Viruses

View full text Add to dashboard Cite

Chikungunya virus (CHIKV) was first extensively described in children during outbreaks in India and South Asia during the mid-1960s. Prior to the 2005 emergence of CHIKV on Reunion Island, CHIKV infection was usually described as a dengue-like illness with arthralgia in Africa and febrile hemorrhagic disease in Asia. Soon after the 2005 emergence, severe CNS consequences from vertical and perinatal transmission were described and as CHIKV continued to emerge in new areas over the next 10 years, severe manifestation of infection and sequelae were increasingly reported in infants and neonates. The following review describes the global reemergence and the syndromes of Chikungunya fever (CHIKF) in infants and children. The various manifestations of CHIKF are described and connected to the viral lineage that was documented in the area at the time the disease was described. The data show that certain manifestations of CHIKF occur with specific viral lineages and genetic motifs, which suggests that severe manifestations of CHIKF in the very young may be associated with the emergence of new viral lineages.

show abstract

Section: Consequences Of Co-infectionmentioning

confidence: 99%

Section: Consequences Of Co-infectionmentioning

confidence: 99%

Chikungunya in Infants and Children: Is Pathogenesis Increasing?

Barr

Vaidhyanathan

2019

Viruses

View full text Add to dashboard Cite

show abstract

Toxoplasma gondii infection in Colombia with a review of hosts and their ecogeographic distribution

Pérez-Grisales

Cruz-Moncada

Sanchez³

et al. 2020

Zoonoses and Public Health

View full text Add to dashboard Cite

Toxoplasma gondii is one of the most prevalent zoonotic protozoan parasites among warm‐blooded animal populations (humans included) around the world, causing multiple clinic manifestations including death in the most severe cases of infection. Due to the versatile life cycle of T. gondii and its diversity of potential hosts, there is a common perception that natural areas and wildlife are highly prevalent reservoirs for the parasite; however, information and reports of the parasite on wildlife populations in Colombia are scarce. Using PRC‐based detection analyses of the B1 gene, we evaluated the presence of T. gondii in 49 native small mammal species (10% of the mammal species of Colombia) from 4 different undisturbed natural habitats. Additionally, to understand the ecogeographical distribution of the parasite in Colombia, we developed a literature search of infection reports including information on the host species, density of records and occurrence patterns (using landcover and ecoregions) in natural, rural and urban areas. Our literature review showed a total of 8,103 reports of T. gondii for Colombia of which 86% were related to humans, and 14% to non‐human mammals and other categories, with just a single report associated to wildlife; additionally, 82% of all reports were associated to urban areas whereas only 18% to rural sites. Based on the negative results for the presence of T. gondii in our PCR‐based analyses and our literature search, we suggest that T. gondii has a synanthropic distribution in Colombia occurring in ecoregions as variable as the xeric scrubs in the northern lowlands and humid montane Andean forests, also we show a lack of information on the parasite relationship with wildlife, a concerning fact given that zoonoses are the leading mechanism for the emergence of infectious diseases.

show abstract

The frequency and clinical presentation of Zika virus coinfections: a systematic review

et al. 2020

View full text Add to dashboard Cite

BackgroundThere is limited knowledge on the influence of concurrent coinfections on the clinical presentation of Zika virus (ZIKV) disease.MethodsTo better understand the types, frequencies and clinical manifestations of ZIKV coinfections, we did a systematic review of four databases (PubMed, Embase, Web of Science, LILACS) without restrictions for studies on ZIKV coinfections confirmed by nucleic acid (quantitative real-time-PCR) testing of ZIKV and coinfecting pathogens. The review aimed to identify cohort, cross-sectional, case series and case report studies that described frequencies and/or clinical signs and symptoms of ZIKV coinfections. Conference abstracts, reviews, commentaries and studies with imprecise pathogen diagnoses and/or no clinical evaluations were excluded.ResultsThe search identified 34 articles from 10 countries, comprising 2 cohort, 10 cross-sectional, 8 case series and 14 case report studies. Coinfections were most frequently reported to have occurred with other arthropod-borne viruses (arboviruses); out of the 213 coinfections described, ZIKV infections co-occurred with chikungunya in 115 cases, with dengue in 68 cases and with both viruses in 19 cases. Other coinfecting agents included human immunodeficiency, Epstein-Barr, human herpes and Mayaro viruses, Leptospira spp, Toxoplasma gondii and Schistosoma mansoni. ZIKV-coinfected cases primarily presented with mild clinical features, typical of ZIKV monoinfection; however, 9% of cases in cohort and cross-sectional studies were reported to experience complications.ConclusionBased on the evidence collated in this review, coinfections do not appear to strongly influence the clinical manifestations of uncomplicated ZIKV infections. Further research is needed to confirm whether risk of severe complications is altered when ZIKV infection co-occurs with other infections.PROSPERO registration numberCRD42018111023.

show abstract

Toxoplasmosis cerebral congénita e infección por el virus del Zika y del chikunguña: reporte de un caso

Cited by 6 publications

References 46 publications

Chikungunya in Infants and Children: Is Pathogenesis Increasing?

Chikungunya in Infants and Children: Is Pathogenesis Increasing?

Toxoplasma gondii infection in Colombia with a review of hosts and their ecogeographic distribution

The frequency and clinical presentation of Zika virus coinfections: a systematic review

Contact Info

Product

Resources

About