Toxoplasmic polymyositis revisited: case report and review of literature

Cuturic, Miroslav; Hayat, Ghazala; Vogler, Carole; Velasques, Alvaro

doi:10.1016/s0960-8966(97)00098-9

Cited by 38 publications

(27 citation statements)

References 21 publications

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“…Bei Toxoplasmose, einer verwandten Parasitose, wirkt Pyrimethamin plus Sulfadiazin am effektivsten gegen Tachyzoiten, jedoch nicht gegen die späteren, enzystierten Bradyzoiten [5,28,31]. Für die seltene Toxoplasmose-Polymyositis wurde in der Akutphase ein Effekt der Antiprotozontherapie beschrieben, während die chronische Phase eine Steroidgabe erforderte [4,7]. Cotrimoxazol erscheint daher im frühen Stadium therapeutisch erfolgversprechend.…”

Section: Zusammenfassung ▼unclassified

Muskuläre Sarkozystose nach Malaysiareise: eine Fallserie aus Deutschland

Slesak¹,

Tappe

Keller

et al. 2014

Dtsch med Wochenschr

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Muscular sarcocystosis develops in a biphasic pattern with initial fever and later prolonged myalgia, eosinophilia, and CK-elevation. Steroids achieve symptomatic relief in the late phase. Early cotrimoxazole-therapy could possibly prevent parasitic muscle invasion. In fever after travel to Malaysia differential diagnosis should include sarcocystosis. The source of infection appears to be located in North-West of Tioman. Further studies are needed, including addressing early diagnosis and treatment.

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Section: Zusammenfassung ▼unclassified

Muskuläre Sarkozystose nach Malaysiareise: eine Fallserie aus Deutschland

Slesak¹,

Tappe

Keller

et al. 2014

Dtsch med Wochenschr

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“…14 Other case reports suggest that Toxoplasma organisms are responsible for inducing polymyositis. 8,15 In these cases, serum anti-Toxoplasma IgG was elevated and muscle biopsy revealed an inflammatory myopathy, but Toxoplasma cysts were not found. Another study suggested that toxoplasmosis does not cause polymyositis.…”

Section: Discussionmentioning

confidence: 87%

“…7 CSF and serum Toxoplasma IgG and IgM levels can be helpful diagnostically if elevated, but may not be positive. 5,8 In a prospective series of 115 AIDS patients with CNS toxoplasmosis, up to 22% lacked serum Toxoplasma IgG and IgM. 9 CSF can be abnormal with protein levels up to 1000 mg/dL, and the number of white blood cells can be normal or elevated up to 500 cells/mm 3 .…”

Section: Discussionmentioning

confidence: 99%

Toxoplasmosis Myelopathy and Myopathy in an AIDS Patient

Kung

Hubenthal²,

Kwan

et al. 2011

The Neurologist

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“…Toxoplasmosis may affect the muscles, during either primary infection or reactivation. Two forms of polymyositis following toxoplasmosis are known: an acute form which is responsive to anti-protozoal therapy and a chronic one manifested by altered immune response and requiring treatment with steroids (Cuturic et al 1997). Toxoplasmic polymyositis recorded in patients with HIV infection and in patients with idiopathic CD4 lymphocytopenia together with the impressive improvement following treatment with prednisolone is suggestive of immunological disturbances contributing to the development of inflammatory myositis through the production of autoantibodies.…”

Section: Protozoa Causing Myositismentioning

confidence: 99%

Parasitic infections and myositis

et al. 2011

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Infectious myositis may be caused by a wide variety of bacterial, fungal, viral, and parasitic agents. Parasitic myositis is most commonly a result of trichinosis, cystericercosis, or toxoplasmosis, but other parasites may be involved. A parasitic cause of myositis is suggested by history of residence or travel to endemic area and presence of eosinophilia. The diagnosis of parasitic myositis is suggested by the clinical picture and radiologic imaging, and the etiologic agent is confirmed by parasitologic, serologic, and molecular methods, together with histopathologic examination of tissue biopsies. Therapy is based on the clinical presentation and the underlying pathogen. Drug resistance should be put into consideration in different geographic areas, and it can be avoided through the proper use of anti-parasitic drugs.

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Toxoplasmic polymyositis revisited: case report and review of literature

Cited by 38 publications

References 21 publications

Muskuläre Sarkozystose nach Malaysiareise: eine Fallserie aus Deutschland

Muskuläre Sarkozystose nach Malaysiareise: eine Fallserie aus Deutschland

Toxoplasmosis Myelopathy and Myopathy in an AIDS Patient

Parasitic infections and myositis

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