Toxoplasma gondii suppresses proliferation and migration of breast cancer cells by regulating their transcriptome
Hengming Ye,
Xiaotao Zhou,
Bike Zhu
et al.
Abstract:Background
Breast cancer is the most common cancer in women worldwide. Toxoplasma gondii (T. gondii) has shown anticancer activity in breast cancer mouse models, and exerted beneficial effect on the survival of breast cancer patients, but the mechanism was unclear.
Methods
The effect of tachyzoites of T. gondii (RH and ME49 strains) on human breast cancer cells (MCF-7 and MDA-MB-231 cells) proliferation and migration was assessed using cell growth … Show more
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