Toxoplasma antibodies by indirect latex agglutination tests in National Seoul Mental Hospital patients

Choi, Won Young; Yoo, Jae Eul; Chung, Chang Seng; Paik, Kang Kyu; Cho, Sung Nam

doi:10.3347/kjp.1983.21.2.281

Cited by 13 publications

(8 citation statements)

References 8 publications

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“…The latex agglutination test (LAT) has been one of the most reliable diagnostic methods for toxoplasmosis for almost 4 decades [7,8,20]. However, its sensitivity has been estimated to be lower than that by ELISA both for serum and cerebrospinal fluid [11].…”

Section: Discussionmentioning

confidence: 99%

Serologic Survey of Toxoplasmosis in Seoul and Jeju-do, and a Brief Review of Its Seroprevalence in Korea

et al. 2012

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Knowledge of the prevalence of human Toxoplasma gondii infection is required in the Republic of Korea. In this study, we surveyed the seroprevalence of T. gondii infection and analyzed the risk factors associated with seropositivity among residents in 2 administrative districts; Seoul and the island of Jeju-do, which have contrasting epidemiologic characteristics. Sera and blood collected from 2,150 residents (1,114 in Seoul and 1,036 in Jeju-do) were checked for IgG antibody titers using ELISA and for the T. gondii B1 gene using PCR. In addition, participants completed a questionnaire that solicited information on gender, age, occupation, eating habits, history of contact with animals, and travel abroad. The T. gondii B1 gene was not detected in all residents examined. However, ELISA showed 8.0% (89 of 1,114 sera) positive for IgG antibodies against T. gondii in Seoul and 11.3% (117 of 1,036 sera) in Jeju-do. In both districts, the positive rates were higher in males than in females, and those 40-79 years of age showed higher rates than other ages. In Seoul, residents older than 70 years of age showed the highest positive rate, 14.9%, whereas in Jeju-do the highest prevalence, 15.6%, was in those in their sixties. The higher seropositive rate in Jeju-do than in Seoul may be related to eating habits and occupations. The present results and a review of related literature are indicative of an increased seroprevalence of T. gondii in Korea in recent years.

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Section: Discussionmentioning

confidence: 99%

Serologic Survey of Toxoplasmosis in Seoul and Jeju-do, and a Brief Review of Its Seroprevalence in Korea

et al. 2012

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“…Concerning T. gondii prevalence in Korea, a study performed in 1960 reported a seropositive rate of 5.6% (Soh et al, 1960) and several studies performed during 1970 and 1989 reported seropositive rates of 1.9-14.3% (Nakayama et al, 1970;Choi et al, 1982;Kim and Choi, 1983;Choi et al, 1983Choi et al, , 1985Choi et al, , 1989. Two recent studies on pregnant women by ELISA reported that the seropositive rate was 7.0% (Im et al, 1991) and 4.3% (Ryu et al, 1996).…”

Section: Discussionmentioning

confidence: 99%

Toxoplasma gondii antibody titers in sera of children admitted to the Seoul National University Children's Hospital

et al. 1999

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A total of 542 children under 10 years of age, admitted to the Seoul National University Children's Hospital, was examined for antibody titers of Toxoplasma gondii using indirect latex agglutination (ILA) test. Among them, 7.7% showed positive titers higher than 1:32, without significant difference between males (7.3%) and females (8.5%). The seropositive rate increased with age although the statistical significance was negligible (0.05

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“…The idea that infection with T. gondii was associated with schizophrenia initially arose from clinical observations of patients infected with T. gondii , presenting with psychotic symptoms (Pariser, Zunich et al 1978; Choi, Yoo et al 1983; Torrey and Yolken 2003). Support for the hypothesis that T. gondii infection may have an etiological role in the development of Schizophrenia has come from numerous studies including: (1) epidemiological studies that have found an higher prevalence of antibodies to T. gondii toxoplasmosis in individuals with schizophrenia; (2).…”

Section: Toxoplasmosis: Clinical Aspectsmentioning

confidence: 99%

Toxoplasmosis

Halonen,

Weiss

2013

Handbook of Clinical Neurology

310

272

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Toxoplasma gondii, an Apicomplexan, is a pathogen that can infect the central nervous system. Infection during pregnancy can result in a congenial infection with severe neurological sequela. In immune compromised individuals reactivation of latent neurological foci can result in encephalitis. Immune competent individuals infected with T. gondii are typically asymptomatic and maintain this infection for life. However, recent studies suggest that these asymptomatic infections may have effects on behavior and other physiological processes. T. gondii infects approximately one-third of the world population, making it one of the most successful parasitic organisms. Cats and other felidae serve as the definite host producing oocysts, an environmentally resistant life cycle stage found in cat feces, which can transmit the infection when ingested orally. A wide variety of warm-blooded animals, including humans, can serve as the intermediate host in which tissue cysts (containing bradyzoites) develop. Transmission also occurs due to ingestion of the tissue cysts. There are 3 predominant clonal lineages, termed types I, II and III and an association with higher pathogenicity with the Type I strains in humans has emerged. This chapter presents a review of the biology of this infection including the life cycle, transmission, epidemiology, parasite strains, and the host immune response. The major clinical outcomes of congenital infection, chorioretinitis, and encephalitis, and the possible association of infection of toxoplasmosis with neuropsychriatric disorders such as schizophrenia, are reviewed.

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Toxoplasma antibodies by indirect latex agglutination tests in National Seoul Mental Hospital patients

Cited by 13 publications

References 8 publications

Serologic Survey of Toxoplasmosis in Seoul and Jeju-do, and a Brief Review of Its Seroprevalence in Korea

Serologic Survey of Toxoplasmosis in Seoul and Jeju-do, and a Brief Review of Its Seroprevalence in Korea

Toxoplasma gondii antibody titers in sera of children admitted to the Seoul National University Children's Hospital

Toxoplasmosis

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