Toxin composition variations in one isolate of the dinoflagellate Alexandrium fundyense

Anderson, Donald M.; Kulis, David M.; Sullivan, John J.; Hall, Sherwood

doi:10.1016/0041-0101(90)90018-3

Cited by 130 publications

(92 citation statements)

References 14 publications

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“…However, recently toxin composition under extreme growth-limited conditions (latestationary phase) or under progressive nitrogen limited conditions (continuous or semicontinuous culture) toxin composition has been shown to change Anderson 1990;Anderson et al 1990b;. Furthermore, the changes in toxin composition that were observed differed between N and P limitation (Anderson et al 1990b).…”

Section: Physiology Toxin Content and Composition Once Methods Of Dmentioning

confidence: 99%

“…Furthermore, the changes in toxin composition that were observed differed between N and P limitation (Anderson et al 1990b). If specific patterns or trends in the toxin content and composition can be resolved for different nutrient limited conditions, then toxin content and or composition could be used as a biomarker specific to Alexandrium.…”

Section: Physiology Toxin Content and Composition Once Methods Of Dmentioning

confidence: 99%

“…For example, during this study and the semi-continuous N-and P-limited experiments conducted by Anderson et al (1990b), the C-toxins, gonyautoxins (GTX), STX and NEO were dominant, whereas in other isolates, these toxins may not be present or are in low abundance. Changes observed during N-limitation for isolates from the Gulf of Maine may not occur in other strains of Alexandrium.…”

Section: Allocation Of Carbon and Nitrogenmentioning

confidence: 99%

“…. The degree to which nutrient limitation effects cellular toxicity during natural blooms is unknown, but toxin production and content have been shown to decrease in nitrogen stressed laboratory cultures (Boyer et al 1985;Anderson et al 1990a;Anderson et al 1990b;.…”

Section: Allocation Of Carbon and Nitrogenmentioning

confidence: 99%

“…Therefore, toxin composition has been used as a chemotaxonomic character that distinguishes isolates of Alexandrium from different geographic regions . Only recently have changes in Alexandrium toxin composition been observed during growth in batch culture (late stationary phase) ), over the cell cycle and in N-and P-limited semi-continuous cultures (Anderson et al 1990b;Taroncher-Oldenburg et al 1997). …”

Section: Allocation Of Carbon and Nitrogenmentioning

confidence: 99%

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Physiological and behavioral diagnostics of nitrogen limitation for the toxic dinoflagellate Alexandrium fundyense

Poulton¹

2000

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Section: Physiology Toxin Content and Composition Once Methods Of Dmentioning

confidence: 99%

Section: Physiology Toxin Content and Composition Once Methods Of Dmentioning

confidence: 99%

Section: Allocation Of Carbon and Nitrogenmentioning

confidence: 99%

Section: Allocation Of Carbon and Nitrogenmentioning

confidence: 99%

Section: Allocation Of Carbon and Nitrogenmentioning

confidence: 99%

See 3 more Smart Citations

Physiological and behavioral diagnostics of nitrogen limitation for the toxic dinoflagellate Alexandrium fundyense

Poulton¹

2000

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Coupling of saxitoxin biosynthesis to the G1 phase of the cell cycle in the dinoflagellateAlexandrin fundyense: temperature and nutrient effects

1999

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The correlation between changes in length of the different cell cycle stages and the toxicity of Alexandrium fundyense Balech was studied in semi-continuous cultures. Growth rates ranging from 0.031 d(-1) to 0.36 d(-1) were established at different temperatures or levels of phosphate limitation. In all treatments, G1 was the phase with the longest duration. Decrease in growth rate was associated with an increase in duration of the different cell cycle stages. Toxin content was always directly correlated to the duration of the G1 phase. In both the temperature treatments and the phosphate limitation experiments, toxin production rates remained constant for the respective range of conditions, implying that the variations in toxin content observed were a result of increasing periods of biosynthetic activity. Toxin accumulation was directly correlated to protein biosynthesis in all temperature treatments. In contrast, toxin content showed little correlation with protein content as phosphate limitation increased. Significant differences in toxin composition were observed between the temperature and phosphate treatments. Total concentrations of GTX II and III and C I and II were significantly higher in the phosphate-limited cultures, while the levels of STX, NEO and gonyautoxins I and IV remained virtually unchanged. We conclude that toxin biosynthesis in A. fundyense is coupled to the G1 phase of the cell cycle, that toxin synthesis is not down-regulated by phosphate deprivation and that interconversions among saxitoxin derivatives are influenced by the availability of phosphate.

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Algal Biotoxins

Landsberg¹,

Vargo²,

and³

et al. 2007

Infectious Diseases of Wild Birds

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Toxin composition variations in one isolate of the dinoflagellate Alexandrium fundyense

Cited by 130 publications

References 14 publications

Physiological and behavioral diagnostics of nitrogen limitation for the toxic dinoflagellate Alexandrium fundyense

Physiological and behavioral diagnostics of nitrogen limitation for the toxic dinoflagellate Alexandrium fundyense

Coupling of saxitoxin biosynthesis to the G1 phase of the cell cycle in the dinoflagellateAlexandrin fundyense: temperature and nutrient effects

Algal Biotoxins

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