Toxicogenomics of Nonviral Cationic Gene Delivery Nanosystems

Omidi, Yadollah; Kafil, Vala; Barar, Jaleh

doi:10.5772/19035

Search citation statements

Order By: Relevance

Paper Sections

Select...

Polymeric Gene Delivery Nanosystems1

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2012

2013

Publication Types

Select...

Other2

Book1

Relationship

Self Cite1

Independent2

Authors

Journals

Cited by 3 publications

(1 citation statement)

References 77 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Cationic polymers (e.g., linear and branched polyethyleneimine (l-PEI and b-PEI), poly(L-lysine), and polyamidoamine (PAMAM) dendrimers) can condense the nucleic acids forming polyplexes as either uni-molecular or multi-molecular complexes. Unfortunately, similar to CLs, cationic polymers can also induce intrinsic toxicogenomics [86] and cytotoxicity [16]. To achieve efficient targetspecific gene transfer, these polymers can covalently be modified by conjugating targeting ligands.…”

Section: Polymeric Gene Delivery Nanosystemsmentioning

confidence: 99%