Toxicity reference values for mink exposed to 2,3,7,8-tetrachlodibenzo-p-dioxin (TCDD) equivalents (TEQs)

Blankenship, Alan L.; Kay, Denise P.; Zwiernik, Matthew J.; Holem, Ryan R.; Newsted, John L.; Hecker, Markus; Giesy, John P.

doi:10.1016/j.ecoenv.2007.08.017

Cited by 22 publications

(23 citation statements)

References 46 publications

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“…Blankenship et al [43] critically reviewed more than 30 published studies in which mink were exposed to PCBs, PCDDs, and PCDFs. They determined that the studies of Bursian et al [38,39] were most appropriate for determining the LOAEC on the basis of TEQs.…”

Section: Discussionmentioning

confidence: 99%

Mercury and halogenated organic contaminants in river otters (Lontra canadensis) in New Jersey, USA

Stansley

Velinsky²,

Thomas³

2010

Enviro Toxic and Chemistry

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Liver samples collected from New Jersey river otters (Lontra canadensis) in 2005 and 2007 were tested for Hg, organochlorine (OC) pesticides, polychlorinated biphenyls (PCBs), polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and polybrominated diphenyl ethers (PBDEs). The highest mercury concentrations were found in otters living in the Pinelands region, where acidic soils and surface waters enhance Hg bioavailability. The highest individual Hg concentration was 19.8 µg/g wet weight, approximately 60% of the experimentally determined lethal threshold. Concentrations of OC pesticides were generally similar to those in otters from areas of Oregon and Washington close to agricultural and industrial sources. The geometric mean total PCB concentration (540 ng/g wet wt) was similar to the concentration in otters from the heavily populated and industrialized lower Columbia River in Oregon and Washington. Seven liver samples that were among the highest in terms of total PCBs were analyzed for PCDDs and PCDFs. Polychlorinated dibenzo-p-dioxins were detected in six of the samples at total concentrations ranging from 172 to 2,783 pg/g wet weight. Polychlorinated dibenzofurans were detected in three of the samples at total concentrations ranging from 1.50 to 2,719 pg/g wet weight. The geometric mean PBDE concentration was 10.6 ng/g wet weight, with a range of 0.82 to 436 ng/g wet weight. No statistically significant relationship was observed between liver contaminant concentrations and land use within an 8-km radius of the trapping location. Overall, the data suggest that contaminant concentrations are not high enough to adversely affect the overall otter population in New Jersey. However, contaminant-related effects on the health or reproductive success of individual otters in some areas are possible.

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Section: Discussionmentioning

confidence: 99%

Mercury and halogenated organic contaminants in river otters (Lontra canadensis) in New Jersey, USA

Stansley

Velinsky²,

Thomas³

2010

Enviro Toxic and Chemistry

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“…CSA is the primary method for assessing risk to wildlife and for deriving criteria for protection of wildlife (CCME 1998 ;US EPA 1995a, b, 2003, 2005Sample and Suter 1993 ) . This method is used to select the critical study for deriving recommended TRVs, which involves fi nding a technically defensible, de fi nitive study from which a toxicity threshold is bracketed by experimental doses (Blankenship et al 2008 ;US EPA 2003 ) . A series of uncertainty factors (UFs) are applied to LOAEL or NOAEL values that are obtained from the critical study, and these are used to determine the TRVs.…”

Section: Methods Of Deriving Trvs and Trcsmentioning

confidence: 99%

“…Because wildlife regularly consume fi sh, toxicity reference values (TRVs) that are based on fi sh tissue concentrations have been developed for 2,3,7,8-tetrachlodibenzo-p -dioxin (TCDD), polychlorinated biphenyls (PCB), per fl uorooctane sulfonate (PFOS), and cadmium (Cd) (Newsted et al 2005 ;Kannan et al 2000 ;Blankenship et al 2008 ;Stanton et al 2010 ) . Moreover, concentrations of contaminants in tissues of wildlife, such as blood and feathers (Kahle and Becker 1999 ;Herring et al 2009 ) , have been used as exposure indices for risk assessments.…”

Section: Introductionmentioning

confidence: 99%

Toxicity Reference Values and Tissue Residue Criteria for Protecting Avian Wildlife Exposed to Methylmercury in China

Zhang

et al. 2012

Reviews of Environmental Contamination and Toxicology

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“…CSA is based on selecting a critical study for deriving recommended TRVs, which involves fi nding a technically defensible and defi nitive study from which a toxicity threshold is bracketed by experimental doses (Blankenship et al 2008 ;USEPA 2003 ). CSA is the primary method for assessing risk to wildlife and for deriving criteria for protection of wildlife (CCME 1998 ;USEPA 1995aUSEPA , b , 2003USEPA , 2005Sample and Suter 1993 ).…”

Section: Approaches To Develop Trvsmentioning

confidence: 99%

Reviews of Environmental Contamination and Toxicology

2014

Reviews of Environmental Contamination and Toxicology

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Toxicity reference values for mink exposed to 2,3,7,8-tetrachlodibenzo-p-dioxin (TCDD) equivalents (TEQs)

Cited by 22 publications

References 46 publications

Mercury and halogenated organic contaminants in river otters (Lontra canadensis) in New Jersey, USA

Mercury and halogenated organic contaminants in river otters (Lontra canadensis) in New Jersey, USA

Toxicity Reference Values and Tissue Residue Criteria for Protecting Avian Wildlife Exposed to Methylmercury in China

Reviews of Environmental Contamination and Toxicology

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