Toxicity of mixtures of λ-cyhalothrin, imidacloprid and cadmium on the earthworm Eisenia fetida by combination index (CI)-isobologram method

Wang, Yanhua; Chen, Chen; Qian, Yongzhong; Zhao, Xueping; Wang, Qiang; Kong, Xiangzhen

doi:10.1016/j.ecoenv.2014.10.015

Cited by 42 publications

(25 citation statements)

References 36 publications

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“…Other authors have demonstrated the low toxicity of the new compound guadipyr to Eisenia fetida, as concentrations of this insecticide in soil below 100 mg/kg in did not affect the growth or the reproduction output. Only increases in enzymatic activities of superoxidase dismutase and catalase were observed in the first few days of exposure, returning to normal levels afterwards (Wang et al 2015a). The 48-h LC50 for acute toxicity of nitenpyram to the earthworm Pheretima posthuma was determined at 0.29 mg/ kg soil (Hussain et al 2017).…”

Section: Effects On Non-target Soil Organismsmentioning

confidence: 98%

An update of the Worldwide Integrated Assessment (WIA) on systemic insecticides. Part 2: impacts on organisms and ecosystems

Pisa

Goulson

Yang

et al. 2017

Environ Sci Pollut Res

188

144

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New information on the lethal and sublethal effects of neonicotinoids and fipronil on organisms is presented in this review, complementing the previous Worldwide Integrated Assessment (WIA) in 2015. The high toxicity of these systemic insecticides to invertebrates has been confirmed and expanded to include more species and compounds. Most of the recent research has focused on bees and the sublethal and ecological impacts these insecticides have on pollinators. Toxic effects on other invertebrate taxa also covered predatory and parasitoid natural enemies and aquatic arthropods. Little new information has been gathered on soil organisms. The impact on marine and coastal ecosystems is still largely uncharted. The chronic lethality of neonicotinoids to insects and crustaceans, and the strengthened evidence that these chemicals also impair the immune system and reproduction, highlights the dangers of this particular insecticidal class (neonicotinoids and fipronil), with the potential to greatly decrease populations of arthropods in both terrestrial and aquatic environments. Sublethal effects on fish, reptiles, frogs, birds, and mammals are also reported, showing a better understanding of the mechanisms of toxicity of these insecticides in vertebrates and their deleterious impacts on growth, reproduction, and neurobehaviour of most of the species tested. This review concludes with a summary of impacts on the ecosystem services and functioning, particularly on pollination, soil biota, and aquatic invertebrate communities, thus reinforcing the previous WIA conclusions .

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Section: Effects On Non-target Soil Organismsmentioning

confidence: 98%

An update of the Worldwide Integrated Assessment (WIA) on systemic insecticides. Part 2: impacts on organisms and ecosystems

Pisa

Goulson

Yang

et al. 2017

Environ Sci Pollut Res

188

144

View full text Add to dashboard Cite

show abstract

“…Effects of pollutant mixtures on earthworms have been investigated (Lydy and Linck 2003;Schreck et al 2008;Gomez-Eyles et al 2009;Zhou et al 2011;Belmeskine et al 2012;Stepić et al 2013a, b;Wang et al 2015;etc. ) and different interactions between mixture compounds-e.g.…”

Section: Effects Of Mixtures On Earthwormsmentioning

confidence: 98%

Important Issues in Ecotoxicological Investigations Using Earthworms

Velki

Ečimović

2016

Reviews of Environmental Contamination and Toxicology

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The importance and beneficial effects of earthworms on soil structure and quality is well-established. In addition, earthworms have proved to be important model organisms for investigation of pollutant effects on soil ecosystems. In ecotoxicological investigations effects of various pollutants on earthworms were assessed. But some important issues regarding the effects of pollutants on earthworms still need to be comprehensively addressed. In this review several issues relevant to soil ecotoxicological investigations using earthworms are emphasized and guidelines that should be adopted in ecotoxicological investigations using earthworms are given. The inclusion of these guidelines in ecotoxicological studies will contribute to the better quantification of impacts of pollutants and will allow more accurate prediction of the real field effects of pollutants to earthworms.

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“…Cedergreen et al (2008) reported that only half of the 158 mixture data were accurately predicted by either CA or IA models. The CI method was successfully used to study the interaction between drugs/chemicals for ecotoxicity risk assessment and reported to have improved the predictive power compared to classical models (Rodea-Palomares et al 2010, González-Pleiter et al 2013, Wang et al 2015b. In this study, the CI method was used to predict the interaction between environmental chemicals in human cell lines and this method is useful to predict the different nature of the interaction between B[a]P and metals at various effect levels.…”

Section: Discussionmentioning

confidence: 99%

“…The interaction is analysed using the median-effect/combination index (CI)-isobologram equation (Chou 2006) which is based on the median-effect principle (mass-action law). This method has been applied to predict the mixture toxicity of environmental chemicals (Rodea-Palomares et al 2010, Wang et al 2015b. One important property of this method is that previous knowledge of the mechanisms of action of each chemical is not required.…”

Section: Combination Index-isobologram Methodsmentioning

confidence: 99%

“…In the recent years, the combination Index (CI) method, which is commonly used for drug combination studies (Chou 2006) has been used to predict the interaction between environmental chemicals for ecotoxicity risk assessment (Rodea-Palomares et al 2010, Wang et al 2015b. One distinct advantage of this model is prior knowledge about the chemicals mode of action is not required in order to determine their interaction.…”

Section: Introductionmentioning

confidence: 99%

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Evaluation of interaction and combined toxicity of polyaromatic hydrocarbons (PAHs) and metals using human cell-based bioassays

Muthusamy¹

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Mixed contamination of polyaromatic hydrocarbons (PAHs) and metals are ubiquitous in the environment. Some of the individual PAHs are known as human carcinogens, and metals are associated with various systemic toxicity and cancers in humans. Although the individual toxicity of PAHs and metals are well documented, our present state of knowledge about the adverse health effects of these mixtures is very limited in terms of exposure associated toxicity in humans, the underlying mechanism of toxicity and predicting the toxicity of mixtures. Due to this, their risk assessment has been mostly carried out based on their individual toxicity data.This research work investigated the interaction and combined toxicity of four PAHs

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Toxicity of mixtures of λ-cyhalothrin, imidacloprid and cadmium on the earthworm Eisenia fetida by combination index (CI)-isobologram method

Cited by 42 publications

References 36 publications

An update of the Worldwide Integrated Assessment (WIA) on systemic insecticides. Part 2: impacts on organisms and ecosystems

An update of the Worldwide Integrated Assessment (WIA) on systemic insecticides. Part 2: impacts on organisms and ecosystems

Important Issues in Ecotoxicological Investigations Using Earthworms

Evaluation of interaction and combined toxicity of polyaromatic hydrocarbons (PAHs) and metals using human cell-based bioassays

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