Toxicity of Chlorpyrifos, Fenubucarb, Monocrotophos, and Methyl Parathion to Fish and Frogs After a Simulated Overflow of Paddy Water

Calumpang, S. M. F.; Medina, M. J. B.; Tejada, A. W.; Medina, J. R.

doi:10.1007/s001289900420

Cited by 12 publications

(4 citation statements)

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“…Larvae scored as malformed, showed often gross alterations in the tail flexure coupled with a great decrease of neuromuscular activity, and these results are well comparable to those of other authors (Snawder and Chambers, 1989;Vismara et al, 1996;Richards and Kendall, 2002). It is well known that in non-target organisms, such as amphibians, fishes, birds and mammals, AChE inhibition is the primary manifestation of toxicity during OP exposure (Thomson et al, 1991;Sultatos, 1994;Calumpang et al, 1997;Fulton and Key, 2001) and that OP compounds produce typical signs of anti-cholinesterase toxicity such as complex posturing movements, body shaking or skeletal muscle fasciculation associated with muscle fibre damages in mammals (Gupta et al, 1987;Karalliedde and Henry, 1993;De Bleecker et al, 1994;John et al, 2003). The abnormal tail flexure observed in CPFs and MTNs could be the consequence of the cholinergic phase, where the AChE inhibition causes repetitive firing of muscle fibres leading to the axis tail folding and, at high concentrations, to paralysis.…”

Section: Discussionsupporting

confidence: 81%

Comparative teratogenicity of Chlorpyrifos and Malathion on Xenopus laevis development

et al. 2004

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Section: Discussionsupporting

confidence: 81%

Comparative teratogenicity of Chlorpyrifos and Malathion on Xenopus laevis development

et al. 2004

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“…Chlorpyrifos (O,O-diethyl O-(3,5,6-trichloro-2-pyridyl)phosphorothioate) is an organophosphate (OP) pesticide that has not been adequately tested for toxicity to anurans [25,26]. Use of chlorpyrifos is high; of all the OPs applied in the United States, chlorpyrifos is used on the most acreage, accounting for approximately 2.8 million ha per year [27].…”

Section: Introductionmentioning

confidence: 99%

Biochemical Effects of Chlorpyrifos on Two Developmental Stages of Xenopus Laevis

Richards¹,

Kendall²

2002

Environ Toxicol Chem

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Abstract-The effects of a 96-h static exposure to chlorpyrifos were examined in two developmental stages of larval Xenopus laevis (premetamorph and metamorph). Measures of effect included mortality, deformity, cholinesterase (ChE) activity, and DNA and protein concentration. All parameters indicated that metamorphs were more sensitive than were premetamorphs. For larvae exposed as premetamorphs, the median lethal concentration and median effective concentration were 14.6 mg/L and 1.71 mg/L; for those exposed as metamorphs, values were 0.56 mg/L and 0.24 mg/L, respectively. Cholinesterase activity was the most sensitive biochemical parameter. Exposure to chlorpyrifos at 0.01 mg/L caused significant decreases in the ChE activity of metamorphs; 0.1 mg/L significantly decreased premetamorph ChE activity. Metamorph DNA was significantly decreased at 0.1 mg/L; premetamorph DNA was not reduced until exposure to 1.0 mg/L. Whole-body protein was the least sensitive biochemical measure of effect. Premetamorphs did not experience a reduction in protein concentrations. Metamorph protein concentration was significantly decreased at 1.0 mg/L. Based on current surface water data, the most sensitive effect would not have a high probability (< or = 4.2%) of occurring in the environment.

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“…In control, we observed that the tadpoles have com- Methyl Parathion and its active metabolite methyl paraoxon are affecting the development of amphibians [1,33]. However, such information of MPT is not available for F. limnocharis.…”

Section: Length and Body Mass Of Tadpolesmentioning

confidence: 99%

Effect of Methyl Parathion on Survival and Development of Tadpoles of Indian Cricket frog Fejervarya limnocharis

Gowda

Vasudev

Krishnamurthy³

2016

JTLS

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Amphibian populations are declining due to various causes including pesticide contamination in natural habitat. We evaluated the effect of Methyl Parathion (MPT) an organophosphate pesticide on survival and development of common paddy field frog Fejervarya limnocharis in a laboratory condition. Effect of 0 µg MPT/L, 500 µg MPT/L, 1000 µg MPT/L, 1500 µg MPT/L, 2000 µg MPT/L and 3000 µg MPT/L was studied using static toxicity test for a duration of 28 days. MPT reduced the survival of tadpole. The mortality was increased with the increased concentration of pesticide. The development decreased with increased MPT concentrations. At higher concentrations, MPT induced slow development and tadpoles failed to metamorphose. It is assumed that slow development could affect the early larval life and amphibian population in the agroecosystem.

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Toxicity of Chlorpyrifos, Fenubucarb, Monocrotophos, and Methyl Parathion to Fish and Frogs After a Simulated Overflow of Paddy Water

Cited by 12 publications

References 1 publication

Comparative teratogenicity of Chlorpyrifos and Malathion on Xenopus laevis development

Comparative teratogenicity of Chlorpyrifos and Malathion on Xenopus laevis development

Biochemical Effects of Chlorpyrifos on Two Developmental Stages of Xenopus Laevis

Effect of Methyl Parathion on Survival and Development of Tadpoles of Indian Cricket frog Fejervarya limnocharis

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