Toxicity comparison between Chattonella marina and Karenia brevis using marine medaka (Oryzias melastigma): Evidence against the suspected ichthyotoxins of Chattonella marina

Shen, Min; Xu, Steven Jing-Liang; Tsang, Tsui Yun; Au, Doris W.T.

doi:10.1016/j.chemosphere.2010.03.051

Cited by 43 publications

(20 citation statements)

References 31 publications

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“…Recently, two related species, the Javanese medaka (O. javanicus) and the Indian medaka (O. dancena, also known as O. melastigma) have been highlighted as new experimental models because they are highly adaptable to high salinity and are expected to become models for marine fish Takei 2002, 2003;Imai et al 2005Imai et al , 2007Koyama et al 2008;Chen et al 2009;Woo et al 2009a, b;Kang et al 2008Kang et al , 2010Shen et al 2010). The two species belong to the O. javanicus group, and closely related each other (Takehana et al 2005).…”

Section: Introductionmentioning

confidence: 97%

Occurrence of two closely related ricefishes, Javanese medaka (Oryzias javanicus) and Indian medaka (O. dancena) at sites with different salinity in Peninsular Malaysia

et al. 2011

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Among ricefishes of the genus Oryzias, the Javanese medaka (O. javanicus) and the Indian medaka (O. dancena) are highly adaptable to seawater. Although wide distribution of the two species in the brackish waters of South and South-East Asia has been reported, their habitat preference remains unknown. We surveyed 12 sites in five estuarial areas of the west coast of Peninsular Malaysia from Kuala Gula to Tanjung Piai. Both species were found in all five areas, suggesting their distribution throughout the west coast of Peninsular Malaysia. This is the southernmostrecorded appearance of O. dancena, to the best of our knowledge. However, the habitats of the two species were essentially separated: of the 12 surveyed sites, the species were found in co-existence at only two sites, and one or the other species was found alone at the remaining 10 sites. We compared temperature, salinity, pH, and dissolved oxygen (DO) at the sampling sites and found that the habitat of O. javanicus is with higher salinity and DO. The salinity and DO at the sites of co-existence are near the lowest values found at the O. javanicus-only sites, and the highest values at the O. dancena-only sites. These results suggest that O. javanicus and O. dancena habitats are essentially separated; the former prefers hyperosmotic conditions while the latter prefers hypoosmotic conditions, and the latter may be more tolerant of hypoxia. The two sites of co-existence are points of contact between the species' separate distribution areas.

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Section: Introductionmentioning

confidence: 97%

Occurrence of two closely related ricefishes, Javanese medaka (Oryzias javanicus) and Indian medaka (O. dancena) at sites with different salinity in Peninsular Malaysia

et al. 2011

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“…Oryzias melastigma has been shown to be a promising marine fish model for ecotoxicological and innate immune studies (Bo et al 2011a, Kong et al 2008; Shen et al 2010). The complement genes MBL-2 , CFP , F2 , and C3 have been identified from our suppression subtractive hybridization (SSH) library of O. melastigma liver (Bo et al 2011b).…”

Section: Introductionmentioning

confidence: 99%

Gender-specific modulation of immune system complement gene expression in marine medaka Oryzias melastigma following dietary exposure of BDE-47

Lei

Lam

et al. 2012

Environ Sci Pollut Res

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BDE-47 is one of the most widely found congeners of PBDEs in marine environments. The potential immunomodulatory effects of BDE-47 on fish complement system were studied using the marine medaka Oryzias melastigma as a model fish. Three-month-old O. melastigma were subjected to short-term (5 days) and long-term (21 days) exposure to two concentrations of BDE-47 (low dose at 290 ± 172 ng/day; high dose at 580 ± 344 ng/day) via dietary uptake of BDE-47 encapsulated in Artemia nauplii. Body burdens of BDE-47 and other metabolic products were analyzed in the exposed and control fish. Only a small amount of debrominated product, BDE-28, was detected, while other metabolic products were all under detection limit. Transcriptional expression of six major complement system genes involved in complement activation: C1r/s (classical pathway), MBL-2 (lectin pathway), CFP (alternative pathway), F2 (coagulation pathway), C3 (the central component of complement system), and C9 (cell lysis) were quantified in the liver of marine medaka. Endogenous expression of all six complement system genes was found to be higher in males than in females (p < 0.05). Upon dietary exposure of marine medaka to BDE-47, expression of all six complement genes were downregulated in males at day 5 (or longer), whereas in females, MBl-2, CFP, and F2 mRNAs expression were upregulated, but C3 and C9 remained stable with exposure time and dose. A significant negative relationship was found between BDE-47 body burden and mRNA expression of C1r/s, CFP, and C3 in male fish (r = −0.8576 to −0.9447). The above findings on changes in complement gene expression patterns indicate the complement system may be compromised in male O. melastigma upon dietary exposure to BDE-47. Distinct gender difference in expression of six major complement system genes was evident in marine medaka under resting condition and dietary BDE-47 challenge. The immunomodulatory effects of BDE-47 on transcriptional expression of these complement components in marine medaka were likely induced by the parent compound instead of biotransformed products. Our results clearly demonstrate that future direction for fish immunotoxicology and risk assessment of immunosuppressive chemicals must include parallel evaluation for both genders.Electronic supplementary materialThe online version of this article (doi:10.1007/s11356-012-0887-z) contains supplementary material, which is available to authorized users.

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“…It is also used to characterize the toxicity of the toxins generated by Chattonella marina and Karenia brevis . Test fishes exposed to the toxins generated by C. marina exhibit hyperventilation, while those exposed to the toxins generated by K. brevis exhibit hypoventilation [49]. With the assistance of the proteomic approach combined with other methods, the toxicological mechanism of aquatic toxins in marine organisms will be elucidated easily and conveniently [36].…”

Section: Utilization Of O Melastigma In Toxicological Studiesmentioning

confidence: 99%

Development of a Promising Fish Model (Oryzias melastigma) for Assessing Multiple Responses to Stresses in the Marine Environment

Dong

Kang

et al. 2014

BioMed Research International

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With the increasing number of contaminants in the marine environment, various experimental organisms have been “taken into labs” by investigators to find the most suitable environmentally relevant models for toxicity testing. The marine medaka, Oryzias melastigma, has a number of advantages that make it a prime candidate for these tests. Recently, many studies have been conducted on marine medaka, especially in terms of their physiological, biochemical, and molecular responses after exposure to contaminants and other environmental stressors. This review provides a literature survey highlighting the steady increase of ecotoxicological research on marine medaka, summarizes the advantages of using O. melastigma as a tool for toxicological research, and promotes the utilization of this organism in future studies.

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Toxicity comparison between Chattonella marina and Karenia brevis using marine medaka (Oryzias melastigma): Evidence against the suspected ichthyotoxins of Chattonella marina

Cited by 43 publications

References 31 publications

Occurrence of two closely related ricefishes, Javanese medaka (Oryzias javanicus) and Indian medaka (O. dancena) at sites with different salinity in Peninsular Malaysia

Occurrence of two closely related ricefishes, Javanese medaka (Oryzias javanicus) and Indian medaka (O. dancena) at sites with different salinity in Peninsular Malaysia

Gender-specific modulation of immune system complement gene expression in marine medaka Oryzias melastigma following dietary exposure of BDE-47

Development of a Promising Fish Model (Oryzias melastigma) for Assessing Multiple Responses to Stresses in the Marine Environment

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