Toxicity bioassay of lead acetate and effects of its sub-lethal exposure on growth, haematological parameters and reproduction in Clarias gariepinus

Hmoud, Fares Alkahemal Balawi; Ahmad, Zubair; Ali, Suliman Al Akel; Fahad, Al Misned; Amin, Mohamad Suliman El; Khalid, Abdullah Al Ghanim

doi:10.5897/ajb11.1463

Cited by 32 publications

(8 citation statements)

References 39 publications

(32 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…On the other hand, there were no significant changes in the hepato-somatic index of C. gariepinus subjected to atrazine [76]. In another study, C. gariepinus exposed to lead acetate showed no significant difference in the HSI after 6 weeks of exposure [70], which may be related to this species being a hardy fish. The downward trend observed in the GSI indicates that glyphosate herbicide exerted a significant negative effect on the gonads as well as the reproductive ability of the red tilapia.…”

Section: Discussionmentioning

confidence: 87%

“…On the other hand, copper supplemented in the feed of blunt snout bream (Megalobrama amblycephala) resulted in a reduction of the feed conversion ratio [69]. Similarly, C. gariepinus exposed to lead for 6 weeks showed a dramatic decline in the food conversion ratio [70]. As far as the effect of glyphosate exposure to the food or feed conversion ratio in fish is concerned, very little to no studies have been reported.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Glyphosate Herbicide Induces Changes in the Growth Pattern and Somatic Indices of Crossbred Red Tilapia (O. niloticus × O. mossambicus)

Muhammad

Yasid

Daud

et al. 2021

Animals

View full text Add to dashboard Cite

The development of glyphosate-resistant genetically modified organisms (GMO) has increased the use of herbicide glyphosate by several magnitudes in recent years. It is now the most commonly used pesticide globally that affects aquatic habitats, especially fish. This study aims to add new knowledge on the effect of technical grade glyphosate on several toxicity parameters and to identify the most effective parameter in predicting technical grade glyphosate chronic toxicity (seven weeks) to fish, especially Malaysia’s heavily farmed red tilapia. The results show that a relatively high concentration of technical grade glyphosate is needed to induce significant changes in all tested parameters. However, the results also indicate that the bodyweight index is the most sensitive toxicity parameter in that a reduction in body weight was observed at 25 mg/L of glyphosate. Negative correlations between the glyphosate concentration and toxicity parameters such as specific growth rate (SGR), hepato-somatic index (HIS), and gonado-somatic index (GSI) were observed. The fish condition factor and feed conversion ratio were found not to be affected at the highest glyphosate concentration tested (150 mg/L). To conclude, crossbred red tilapia (O. niloticus × O. mossambicus) is one potential species for evaluating the toxic effects of technical grade glyphosate on fish.

show abstract

Section: Discussionmentioning

confidence: 87%

Section: Discussionmentioning

confidence: 99%

Glyphosate Herbicide Induces Changes in the Growth Pattern and Somatic Indices of Crossbred Red Tilapia (O. niloticus × O. mossambicus)

Muhammad

Yasid

Daud

et al. 2021

Animals

View full text Add to dashboard Cite

show abstract

“…Kumar et al (2021) reported a dose‐dependent increase of ALP, SGOT and SGPT in Puntius ticto after Pb exposure. Alkahemal‐Balawi et al (2011) also reported similar increase in SGOT and SGPT in Pb‐exposed Clarias gariepinus . A recent study by Vijayadurga, Shameem, Paul, and Kumar (2023) demonstrated an increase in the SGOT, SGPT and ALP in lead nitrate exposed Indian major carp, Labeo rohita .…”

Section: Introductionmentioning

confidence: 68%

Environmentally relevant lead alters nuclear integrity in erythrocytes and generates oxidative stress in liver of Anabas testudineus: Involvement of Nrf2‐Keap1 regulation and expression of biomarker genes

Dey,

Mondal,

Chattopadhyay

2023

J of Applied Toxicology

View full text Add to dashboard Cite

Genotoxic and hepatotoxic effects of lead (Pb) on a freshwater fish, climbing perch (Anabas testudineus) were studied at an environmentally relevant concentration (43.3 ppm). The genotoxic potential of Pb was confirmed by micronucleus study, with increased frequencies of erythrocytic nuclear alterations like lobed, blebbed, notched, fragmented, and micronuclei were observed in erythrocytes in treated groups as compared to control. Inorganic Pb induces oxidative stress which is a consequence of elevated level of Reactive Oxygen Species. Hepatotoxicity was assessed both by the oxidative stress and cellular responses that emerged due to the toxic assault of Pb in the liver, the most important detoxifying organ. Upregulation of xenobiotic metabolizing enzyme like catalase was evident after 15, 30, and 90 days of exposure, and a profound effect was observed on 30th days. The level of lipid peroxidation and reduced glutathione was increased after Pb exposure. Histoarchitectural damages of liver were distinctly evident in treated fish. Western blot analysis confirmed the expressional alterations of stress‐responsive marker proteins like Nrf2, Keap1, Hsp70, and Nqo1. Pb exposure resulted in increased expression of Hsp70, Nrf2, and Nqo1, whereas Keap1 was downregulated, suggesting the involvement of Nrf2‐Keap1 regulation as a cytoprotective mechanism against Pb toxicity.

show abstract

“…Poor water quality will have an impact on fish and other aquatic species, which will cause death and behavioural changes [23]. The behavioural response seen when O. niloticus was exposed to PP is comparable to that seen when Cyprinus carpio was exposed to various doses of fenthion by Alkahemal-Balawi et al [24]. The fishes in treatment groups that were exposed to PP in this study displayed some abnormal behaviour, such as air gulping, erratic swimming, deformed fins, and moulting, which are caused by inhibition of acetylcholinesterase activity.…”

Section: Discussionmentioning

confidence: 99%

Effects of Pretilachor Pyribenzoxim Pollution on the Water Quality, Serum Biochemical Indices, and Behavioural Response of Oreochromis niloticus Juveniles

Adene

2023

AJRAF

View full text Add to dashboard Cite

Aims: The effects of Pretilachor pyribenzoxim (PP) pollution on the water quality, serum biochemical indices, and behavioural response of Oreochromis niloticus Juveniles were studied. Study Design: The completely randomized design was used in this study. Place and Duration of Study: The experiment was carried out in the Central Laboratory of the Fisheries and Aquaculture Department, Faculty of Agriculture, Adekunle Ajasin University Akungba-Akoko, Nigeria, between January and March 2023. Methodology: The experiment was carried out in 30 L of non-chlorinated and aerated water in rectangular plastic tanks (45cm x 30cm x 30cm). 250 juveniles O. niloticus of both sexes were collected from Federal University of Technology, Akure, Ondo state and acclimatized for 14days in the laboratory. During rearing period, the fish were fed coppen feed at 2% body weight. In a definitive test, a group of 10 fish specimen (11.3-17.5cm length and 10.5-32.3g weight) were treated at random to nominal PP doses of 0.0, 0.10, 0.125, 0.150, 0.175, and 0.2 ml being diluted in 30 litres of water and labelled T1. T2, T3, T4, T5 and T6, respectively in triplicate. The LC50 of PP, test water's physicochemical, behavioural responses and serum biochemical indices were determined. Results: The dissolved oxygen depleted (P<0.05) in T5 and T6, compared to T1 and the rest of the treatments. The water conductivity increases (P<0.05) with an increased concentration of PP contamination. The water's total dissolved solids levels increased progressively with an increase in PP concentration. The total dissolved solids in T5 and T6 were similar (P>0.05) to T4 but lower (P<0.05) than T1 and T2. Juveniles in treatments 2, 3, 4, 5 and 6 shows behavioural responses such as loss of reflex, fin deformation, erratic swimming, air gulping, and moulting. The serum total protein of the juveniles in treatments 2, 3, 4, 5 and 6 was lower (P<0.05) than T1. Serum creatinine level increased with increased PP contamination from treatments 1 to 6. The serum aspartate aminotransferase (AST) of the juvenile in T3, T4, T5 and T6 were higher (P<0.05) than in T1. The serum Alanine aminotransferase (ALT) of the juvenile in T2, T3, T4, T5 and T6 were significantly (P<0.05) higher than T1. Conclusion: The exposure of juvenile O.niloticus to PP contamination affected the physicochemical properties of water, behaviour and Serum biochemicals of juvenile O. niloticus fish. Hence, leaching of pp into water bodies through Agricultural activities should be mornitored to reduce lost of fish which can lead to economic detune.

show abstract

Toxicity bioassay of lead acetate and effects of its sub-lethal exposure on growth, haematological parameters and reproduction in Clarias gariepinus

Cited by 32 publications

References 39 publications

Glyphosate Herbicide Induces Changes in the Growth Pattern and Somatic Indices of Crossbred Red Tilapia (O. niloticus × O. mossambicus)

Glyphosate Herbicide Induces Changes in the Growth Pattern and Somatic Indices of Crossbred Red Tilapia (O. niloticus × O. mossambicus)

Environmentally relevant lead alters nuclear integrity in erythrocytes and generates oxidative stress in liver of Anabas testudineus: Involvement of Nrf2‐Keap1 regulation and expression of biomarker genes

Effects of Pretilachor Pyribenzoxim Pollution on the Water Quality, Serum Biochemical Indices, and Behavioural Response of Oreochromis niloticus Juveniles

Contact Info

Product

Resources

About