Toxicity and biodegradability of sulfonamides and products of their photocatalytic degradation in aqueous solutions

Baran, W.; Sochacka, Jolanta; Wardas, W.

doi:10.1016/j.chemosphere.2006.04.040

Cited by 235 publications

(104 citation statements)

References 12 publications

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“…Therefore, under the present experimental conditions the high stability of STZ in seawater is in agreement with other researches that state SA drugs are resistant to degradation and can persist for long time periods in the environment (Halling-Sørensen et al, 1998;Kümmerer, 2001Kümmerer, , 2009Baran et al, 2006;García-Galán et al, 2008).…”

Section: Degradation Of Stz In Watersupporting

confidence: 92%

“…Pro et al (2003) tested the influence of sulfachlorpyridazine on Lemna minor at several concentrations and the same trend of inhibition after 120 h was registered for all levels above 3 lg mL À1 . Another study by Baran et al (2006) reported that, along with other substances tested, STZ caused inhibition to the green algae Chlorella vulgaris.…”

Section: Growthmentioning

confidence: 98%

“…The resulting deficiency in folates will have severe consequences on cell division that in turn will be translated in diminished growth. Nonetheless, studies have demonstrated that STZ-induced inhibition is concentration and time dependent (Brain et al, 2004;Baran et al, 2006;Park and Choi, 2008). The dosages tested in the present work are very high and only likely to be found in natural ecosystems in areas at and very close to discharge points from aquaculture systems and therefore it is not expected that the tested prophylactic and therapeutic concentrations of STZ will have a severe impact on macroalgal growth in the concentrations usually reported for environmental waters, which are in the ng L À1 to lg L À1 range.…”

Section: Growthmentioning

confidence: 99%

“…The available studies on STZ's ecotoxicity to non-target organisms (e.g. bacteria, microalgae, plants, invertebrates and fish) include acute and chronic effects demonstrated in inhibition of growth (Brain et al, 2004;Baran et al, 2006;Kim et al, 2009;Ji et al, 2012). Due to SA's amphoteric nature the extent to which the current filtering systems and depuration actions can prevent their release to the environment is strongly related with their sorption capacity, which in turn is dependent on soil/ sediment composition and pH (Halling-Sorensen et al, 1998;Kahle and Stamm, 2007;García-Galán et al, 2008;Lertpaitoonpan et al, 2009;Braschi et al, 2010;Hruska and Franek, 2012).…”

Section: Introductionmentioning

confidence: 99%

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The influence of sulfathiazole on the macroalgae Ulva lactuca

et al. 2014

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h i g h l i g h t sSulfathiazole shows high stability in seawater with 18% degradation over 5 d. Ulva lactuca reduced the concentrations of STZ in the water by efficiently taking up the drug. U. lactuca kept the internal values constant most likely through a detoxification mechanism. Sulfathiazole slightly inhibited the growth of U. lactuca after 96 h of exposure. Macroalgae should be considered as potential bioindicator species in risk assessment of STZ. Sulfonamides (SA) are a class of antibiotics routinely found in environmental matrices and therefore their role as contaminants should be investigated in non-target organisms. With this purpose the present experimental work has evaluated the exposure of the chlorophycean Ulva lactuca L. to sulfathiazole (STZ), a SA drug commonly used in aquaculture, at two concentrations representing prophylactic (25 lg mL À1 ) and therapeutic (50 lg mL À1 ) administrations. Results showed that STZ exhibits high stability in seawater with only 18% degradation over the 5 d assay at both dosages tested. Also, macroalgae demonstrated an efficient uptake capacity with constant internal concentrations after 24 h regardless of the external solutions and thus should be considered as a bioindicator species in risk assessment. Both STZ concentrations induced a slight inhibition of the macroalgae growth after 96 h. a r t i c l e i n f o

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Section: Degradation Of Stz In Watersupporting

confidence: 92%

Section: Growthmentioning

confidence: 98%

Section: Growthmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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The influence of sulfathiazole on the macroalgae Ulva lactuca

et al. 2014

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“…Antibiotics are a class of commonly used PPCPs used as human and veterinary medicine. Due to their pseudo-persistent nature and potential to cause antibiotic resistant bacteria and genes (Baran et al, 2006;Zhang et al, 2013;Guo et al, 2013), it is imperative to study the fate and transport of antibiotics and their impacts in the natural environment (Ge et al, 2009(Ge et al, , 2010Guo et al, 2013).…”

Section: Introductionmentioning

confidence: 99%

Photodegradation of sulfapyridine under simulated sunlight irradiation: Kinetics, mechanism and toxicity evolvement

Hao

Guo

et al. 2014

Chemosphere

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h i g h l i g h t sSulfapyridine was effectively photodegraded under UV-vis irradiation. Factors affecting the photodegradation process were investigated. Degradation intermediates were identified and possible pathway was proposed. Bioassay test showed reaction products were much more toxic than parent compound. a r t i c l e i n f o t r a c tIn this study, the photoinduced degradation of sulfapyridine (SPY) was investigated under simulated light irradiation (k > 200 nm). The effect of pH and main water constituents including nitrate ion, bicarbonate, dissolved organic matter (DOM) and iron(III) on the photodegradation was explored. SPY was effectively removed in aqueous solution at pH 8 under UV-vis irradiation, with removal efficiency of 100% within 120 min. DOM and iron(III) had retarding influence on the SPY removal, whereas nitrate ion and bicarbonate did not show any obvious effect. Under UV-vis irradiation, the formation of singlet oxygen ( 1 O 2 ) accelerated the SPY photodegradation and the contribution of indirect photolysis due to reaction with 1 O 2 was up to 42%. The transformation products of SPY were identified by HPLC-MS and the possible photoreaction pathways were proposed. It showed that photoinduced hydrolysis, photo-oxidation via 1 O 2 and desulfonation were the main degradation ways for SPY decomposition. Toxicity assays by Vibrio fischeri proved that the transformation products were more toxic than the parent compound.

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Methods for the Destruction of Pharmaceuticals in the Laboratory

Lunn¹,

Sansone²

2012

Destruction of Hazardous Chemicals in the Laboratory

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Toxicity and biodegradability of sulfonamides and products of their photocatalytic degradation in aqueous solutions

Cited by 235 publications

References 12 publications

The influence of sulfathiazole on the macroalgae Ulva lactuca

The influence of sulfathiazole on the macroalgae Ulva lactuca

Photodegradation of sulfapyridine under simulated sunlight irradiation: Kinetics, mechanism and toxicity evolvement

Methods for the Destruction of Pharmaceuticals in the Laboratory

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