Toxic-shock-Syndrom nach offener Sprunggelenkverletzung

Abstract

The treatment of open fractures is a challenge for the attending surgeon. Depending on the severity, the risk of infection rises up to 50%. Local infection up to the point of sepsis can develop in spite of surgical and antimicrobial therapy. The present case demonstrates the case of an 18-year-old man who developed toxic shock syndrome (TSS) after an open ankle fracture. This potentially life-threating syndrome usually presents with the main symptoms of fever, hypotension and exanthema and is caused by toxins, such as toxic shock syndrome toxin 1 (TSST-1) and staphylococcal enterotoxins A-D. In some cases it is associated with cardiopulmonary decompensation and can rapidly progress to multiorgan failure.

Molecular and phenotypic characterization of Staphylococcus aureus strains isolated from carcass swabs and carcass drips of chickens slaughtered in the informal market in Gauteng Province, South Africa

“…A total of 19.6% of all S. aureus isolates in our study were positive for tst gene, a much higher frequency than those reported by other researchers (0.0% to 3.5%) Li et al, 2018;Marek, Pyzik, Stępień-Pyśniak, Urban-Chmiel, & Nowaczek, 2018;Sallam, Abd-Elghany, Elhadidy, & Tamura, 2015). The presence of tst gene in high frequency of S. aureus poses a zoonotic risk to chicken handlers as previous works confirmed that TSST-producing S. aureus had caused human diseases (Klüter et al, 2015;Sharma et al, 2018). This is the first documentation of S. aureus strains with tst positive genes from animal, food or human sources in South Africa.…”