Toxic Myopathies

McIntosh, Paul; Doughty, Christopher

doi:10.1007/s11940-022-00718-3

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2024

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“…There have been no previous reports of corticosteroid or disease-modifying-antirheumatic-drugs use in the treatment of isotretinoin-induced myositis [ 3 ]. In selected cases of drug-induced myopathies, such as following statin exposure, removal of causative medication has been noted to be insufficient, requiring the use of immunosuppression [ 9 ].…”

Section: Discussionmentioning

confidence: 99%

Isotretinoin-induced myositis

Hague,

Thanopoulou,

Mangat

et al. 2024

Oxford Medical Case Reports

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Retinoid-induced myositis is a phenomenon recognised in multiple case reports. We report a case of isotretinoin-induced myositis in an 18-year-old male patient. This case adds to the published literature as it demonstrates (i) myositis may occur after extended periods of isotretinoin use, (ii) should be considered as a differential diagnosis even when presenting asymmetrically and (iii) can continue to progress clinically and biochemically initially following the suspension of isotretinoin before being effectively treated with corticosteroids.

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Section: Discussionmentioning

confidence: 99%