Toxic Metabolites and Lipopolysaccharides from Pseudomonas cichorii

Lazzaroni, Silvia; Evidente, Antonio; Surico, Giuseppe

doi:10.1007/978-94-017-0133-4_25

Cited by 4 publications

(2 citation statements)

References 8 publications

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“…The bacterium also produces several as yet uncharacterized toxins (Hu et al. 1998; Lazzaroni et al. 2003) but their role in pathogenicity is not yet elucidated.…”

Section: Discussionmentioning

confidence: 99%

Epidemiology of Pseudomonas cichorii, the Cause of Lettuce Midrib Rot

Pauwelyn¹,

Vanhouteghem²,

Cottyn³

et al. 2010

Journal of Phytopathology

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Bacterial midrib rot, caused by Pseudomonas cichorii, has become a serious threat to the production of greenhouse butterhead lettuce (Lactuca sativa L. var. capitata) in Belgium. Currently, there are no strategies for controlling this pathogen. Therefore, greenhouse experiments were conducted to obtain more knowledge about the epidemiology of P. cichorii on butterhead lettuce. Greenhouse butterhead lettuce becomes susceptible to lettuce midrib rot infections at head formation, and a single overhead irrigation with water containing 10 2 CFU ⁄ ml P. cichorii was sufficient to cause disease. The use of surface drip irrigation instead of overhead sprinkler irrigation significantly reduced midrib rot incidence in the greenhouse. P. cichorii isolates can be divided into subgroups based on BOX-PCR genomic fingerprinting, with isolates belonging to subgroup C1 and C2 being more virulent than those of (or related to) subgroup C3. P. cichorii infections with distinct symptoms comparable to midrib rot have also been observed on field-grown crisphead lettuce in California and Japan which, respectively, are referred to as Ôvar-nish spotÕ or ÔtarÕ. We showed that symptom expression is strongly influenced by the lettuce cultivar group, irrespective of the P. cichorii isolate, resulting in varnish spot ⁄ tar on crisphead lettuce and midrib rot on butterhead or cutting group lettuce.

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“…The bacterium also produces several as yet uncharacterized toxins (Hu et al. 1998; Lazzaroni et al. 2003) but their role in pathogenicity is not yet elucidated.…”

Section: Discussionmentioning

confidence: 99%

Epidemiology of Pseudomonas cichorii, the Cause of Lettuce Midrib Rot

Pauwelyn¹,

Vanhouteghem²,

Cottyn³

et al. 2010

Journal of Phytopathology

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“…Pseudomonas chicorii is a pathogen that causes necrotic leaf and stem lesions on several agrarian plants, including lettuce celery, chrysanthemum, tomato, coffee and soybean [ 58 , 59 , 60 , 61 , 62 ]. This bacterium produces phytotoxic metabolite whose role in pathogenesis is not yet demonstrated [ 63 , 64 , 65 , 66 ]. Two LPDs, named cichopeptins A and B ( 46 and 47 , Figure 7 ) were isolated from the culture filtrate of P. chicorii .…”

Section: Source Isolation and Biological Activity Of Bacterial Lipode...mentioning

confidence: 99%

Bioactive Lipodepsipeptides Produced by Bacteria and Fungi

Evidente

2022

IJMS

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Natural products are a vital source for agriculture, medicine, cosmetics and other fields. Lipodepsipeptides (LPDs) are a wide group of natural products distributed among living organisms such as bacteria, fungi, yeasts, virus, insects, plants and marine organisms. They are a group of compounds consisting of a lipid connected to a peptide, which are able to self-assemble into several different structures. They have shown different biological activities such as phytotoxic, antibiotic, antiviral, antiparasitic, antifungal, antibacterial, immunosuppressive, herbicidal, cytotoxic and hemolytic activities. Their biological activities seem to be due to their interactions with the plasma membrane (MP) because they are able to mimic the architecture of the native membranes interacting with their hydrophobic segment. LPDs also have surfactant properties. The review has been focused on the lipodepsipeptides isolated from fungal and bacterial sources, on their biological activity, on the structure–activity relationships of some selected LPD subgroups and on their potential application in agriculture and medicine. The chemical and biological characterization of lipodepsipeptides isolated in the last three decades and findings that resulted from SCI-FINDER research are reported. A critical evaluation of the most recent reviews dealing with the same argument has also been described.

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Characterization of Cichopeptins, New Phytotoxic Cyclic Lipodepsipeptides Produced by Pseudomonas cichorii SF1-54 and Their Role in Bacterial Midrib Rot Disease of Lettuce

Huang

Pauwelyn

Ongena

et al. 2015

MPMI

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The lettuce midrib rot pathogen Pseudomonas cichorii SF1-54 produces seven bioactive compounds with biosurfactant properties. Two compounds exhibited necrosis-inducing activity on chicory leaves. The structure of the two phytotoxic compounds, named cichopeptin A and B, was tentatively characterized. They are related cyclic lipopeptides composed of an unsaturated C12-fatty acid chain linked to the N-terminus of a 22-amino acid peptide moiety. Cichopeptin B differs from cichopeptin A only in the last C-terminal amino acid residue, which is probably Val instead of Leu/Ile. Based on peptide sequence similarity, cichopeptins are new cyclic lipopeptides related to corpeptin, produced by the tomato pathogen Pseudomonas corrugata. Production of cichopeptin is stimulated by glycine betaine but not by choline, an upstream precursor of glycine betaine. Furthermore, a gene cluster encoding cichopeptin synthethases, cipABCDEF, is responsible for cichopeptin biosynthesis. A cipA-deletion mutant exhibited significantly less virulence and rotten midribs than the parental strain upon spray inoculation on lettuce. However, the parental and mutant strains multiplied in lettuce leaves at a similar rate. These results demonstrate that cichopeptins contribute to virulence of P. cichorii SF1-54 on lettuce.

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Toxic Metabolites and Lipopolysaccharides from Pseudomonas cichorii

Cited by 4 publications

References 8 publications

Epidemiology of Pseudomonas cichorii, the Cause of Lettuce Midrib Rot

Epidemiology of Pseudomonas cichorii, the Cause of Lettuce Midrib Rot

Bioactive Lipodepsipeptides Produced by Bacteria and Fungi

Characterization of Cichopeptins, New Phytotoxic Cyclic Lipodepsipeptides Produced by Pseudomonas cichorii SF1-54 and Their Role in Bacterial Midrib Rot Disease of Lettuce

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