Toxic heavy metal ion detection by fluorescent nanocarbon sensor derived from a medicinal plant

Sreehari, K.S.; Namratha, W.N.; Joseph, Neethu; Balachandran, Manoj

doi:10.1016/j.rechem.2022.100720

Cited by 5 publications

(3 citation statements)

References 21 publications

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“…The chemical element Cd has the atomic number 48. This silvery white and soft metal is chemically similar to the other two stable metals (zinc and mercury) in group 12 ( 170 , 171 ). It is a heavy metal that is both naturally present and released as part of industrial pollution ( 172 ).…”

Section: Heavy Metals: Their Toxicity Mechanism and Effectsmentioning

confidence: 67%

“…The toxic effects of Cd include lung damage, hypertension, hepatic injury, and kidney dysfunction ( 187 , 188 ). High amounts of Cd have been discovered in the kidneys, muscles, bones, and liver of cattle in Marrakech, Morocco ( 186 , 189 ) where the sewage treatment fields have disrupted the normal metabolism of trace elements and reduced the levels of Zn and Cu ( 171 , 190 ). Cattle slow the cellular clearance of Cd and the ineffectiveness of cellular export systems accounts for the element's prolonged retention in storage tissues such as the colon, the liver, and the kidneys ( 37 , 191 , 192 ).…”

Section: Heavy Metals: Their Toxicity Mechanism and Effectsmentioning

confidence: 99%

“…Cadmium toxicity has been observed in many organs and Cd induces tissue damage through oxidative stress ( 194 , 195 ), epigenetic alterations in DNA expression ( 196 ), and upregulation and inhibition of the transport pathway ( 197 ), especially in proximal S1 region in tubules of the kidney ( 198 , 199 ). The kidney is the main organ affected by Cd toxicity ( 171 ), and the S1 portion of the proximal tubule is a prime target for Cd deposition. As a result of Cd-induced oxidative damage to carrier proteins and mitochondria ( 181 ), Fanconi syndrome is characterized by clinically visible defects in protein, bicarbonate, phosphate, and amino acid reabsorption ( 200 , 201 ).…”

Section: Heavy Metals: Their Toxicity Mechanism and Effectsmentioning

confidence: 99%

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A review of important heavy metals toxicity with special emphasis on nephrotoxicity and its management in cattle

Tahir

Alkheraije

2023

Front. Vet. Sci.

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Toxicity with heavy metals has proven to be a significant hazard with several health problems linked to it. Heavy metals bioaccumulate in living organisms, pollute the food chain, and possibly threaten the health of animals. Many industries, fertilizers, traffic, automobile, paint, groundwater, and animal feed are sources of contamination of heavy metals. Few metals, such as aluminum (Al), may be eliminated by the elimination processes, but other metals like lead (Pb), arsenic (As), and cadmium (Ca) accumulate in the body and food chain, leading to chronic toxicity in animals. Even if these metals have no biological purpose, their toxic effects are still present in some form that is damaging to the animal body and its appropriate functioning. Cadmium (Cd) and Pb have negative impacts on a number of physiological and biochemical processes when exposed to sub-lethal doses. The nephrotoxic effects of Pb, As, and Cd are well known, and high amounts of naturally occurring environmental metals as well as occupational populations with high exposures have an adverse relationship between kidney damage and toxic metal exposure. Metal toxicity is determined by the absorbed dosage, the route of exposure, and the duration of exposure, whether acute or chronic. This can lead to numerous disorders and can also result in excessive damage due to oxidative stress generated by free radical production. Heavy metals concentration can be decreased through various procedures including bioremediation, pyrolysis, phytoremediation, rhizofiltration, biochar, and thermal process. This review discusses few heavy metals, their toxicity mechanisms, and their health impacts on cattle with special emphasis on the kidneys.

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Section: Heavy Metals: Their Toxicity Mechanism and Effectsmentioning

confidence: 67%

Section: Heavy Metals: Their Toxicity Mechanism and Effectsmentioning

confidence: 99%

Section: Heavy Metals: Their Toxicity Mechanism and Effectsmentioning

confidence: 99%

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A review of important heavy metals toxicity with special emphasis on nephrotoxicity and its management in cattle

Tahir

Alkheraije

2023

Front. Vet. Sci.

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Titania Doped CDs as Effective CT‐DNA Binders: A Novel Fluorescent Probe via Green Synthesis

W. N,

Joseph,

Varghese

et al. 2024

Part & Part Syst Charact

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Carbon dots (CDs), which belong to the class of zero‐dimensional carbon‐based nanomaterials, have garnered significant interest owing to their wide array of applications spanning from the electronics industry to the healthcare sector. This work employs a facile, inexpensive approach to synthesize green luminescent carbon dots (J‐10) from a potential medicinal plant named Justicia Wynaadensis by the one‐step hydrothermal method. A nanocomposite (JT‐10) of the CDs is prepared by adding TiO2 nanoparticles derived from green synthesis of Lavandula leaves. The J‐10 and JT‐10 are further characterized by X‐ray Diffraction spectroscopy (XRD), Transmission Electron Microscopy (TEM), Raman analysis X‐ray Photoelectron Spectroscopy (XPS), and Fourier transform infrared techniques (FTIR), UV–vis spectroscopy, Photoluminescence (PL), and Fluorescence or PL lifetime analysis. The average size of synthesized CDs is 1.85 nm and exhibits an excitation‐dependent fluorescence nature at 320 nm. PL lifetime analysis of J‐10 and JT‐10 is calculated to be 5.80 and 2.84 ns respectively. Offering these unique optical properties and biocompatibility, the synthesised material is suitable for investigating their binding affinity and interaction mechanisms with DNA. The use of JT‐10 in DNA binding studies contributes to the development of sustainable and efficient nanomaterials for applications in biosensors, drug delivery, and gene therapy.

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Biomass Derived Fluorescent Nanocarbon Sensor for Effective Sensing of Toxic Cadmium Metal Ions

Neethu,

Ann,

Manoj

2023

Springer Proceedings in Materials

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Toxic heavy metal ion detection by fluorescent nanocarbon sensor derived from a medicinal plant

Cited by 5 publications

References 21 publications

A review of important heavy metals toxicity with special emphasis on nephrotoxicity and its management in cattle

A review of important heavy metals toxicity with special emphasis on nephrotoxicity and its management in cattle

Titania Doped CDs as Effective CT‐DNA Binders: A Novel Fluorescent Probe via Green Synthesis

Biomass Derived Fluorescent Nanocarbon Sensor for Effective Sensing of Toxic Cadmium Metal Ions

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