2013
DOI: 10.5152/tud.2013.010
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Toxic effects of formaldehyde on the urinary system

Abstract: Formaldehyde is a chemical substance with a pungent odor that is highly soluble in water and occurs naturally in organisms. Formaldehyde, when taken into organisms, is metabolized into formic acid in the liver and erythrocytes and is then excreted, either with the urine and feces or via the respiratory system. Formaldehyde is widely used in the industrial and medical fields, and employees in these sectors are frequently exposed to it. Anatomists and medical students are affected by formaldehyde gas during diss… Show more

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Cited by 38 publications
(22 citation statements)
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“…It reaches the body either through inhalation, ingestion or skin contact (Wilbur et al, 1999). After absorption, formaldehyde is usually metabolized by liver and other tissues into a non-toxic metabolite known as formate which excreted through the urine or converted to carbon dioxide and excreted through the exhalation (Inci et al, 2013). The exposure to formaldehyde vapors with a high dose results in many health problems.…”
Section: Introductionmentioning
confidence: 99%
“…It reaches the body either through inhalation, ingestion or skin contact (Wilbur et al, 1999). After absorption, formaldehyde is usually metabolized by liver and other tissues into a non-toxic metabolite known as formate which excreted through the urine or converted to carbon dioxide and excreted through the exhalation (Inci et al, 2013). The exposure to formaldehyde vapors with a high dose results in many health problems.…”
Section: Introductionmentioning
confidence: 99%
“…Bladder cancer is considered as the ninth most common cancer. Bladder cancer is primarily led by the continual accumulation of toxic chemicals in urine, such as tobacco smoke (2-Naphthylamine), pioglitazone, and formaldehyde [80]. However, the established link between pioglitazone and bladder cancer is still controversial.…”
Section: Elucidating Side Effects Of Tzdsmentioning
confidence: 99%
“…However, contact dermatitis, congenital defects, and cancer were results of long-term exposure to formaldehyde [6]. The effects of formaldehyde on human vary on the concentration level of exposure: 0.05-1.05 ppm could lead to neurophysiologic effect; 0.05-1.0 ppm was considered the respiration air threshold; 0.05-2.0 ppm could cause ocular irritation; 0.1-2.5 ppm could cause upper respiratory tract irritation; 5.0-30 ppm had severe effects on the lungs and lower respiratory tract; 50-100 ppm could cause pneumonia and pulmonary edema; and ≥100 ppm could lead to death [7].…”
Section: Introductionmentioning
confidence: 99%