Toxic effects of certain pentacyclic triterpenoids on early embryogenesis of the sea urchin

Anisimov, M. M.; Shentsova, E. B.; Shcheglov, V.V.; Strigina, L. I.; Chetyrina, N. S.; Aladjina, N.G.; Vecherko, L. P.; Zorina, A. D.; Matyukhina, L. G.; Saltykova, I. A.

doi:10.1016/0041-0101(76)90021-0

Cited by 6 publications

(2 citation statements)

References 11 publications

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“…The highest antifungal activity was found in the triterpene glycosides oleanolic acid and hederagenin, which have a free carboxyl group at C-28. Triterpenes of the meristotropic acid, macedonic acid, and lupan types had no fungistatic activity at concentrations up to 100 microgram/mL [63].…”

Section: Anticomplement Activities Of Oleanolic Acid Monodesmosides Amentioning

confidence: 99%

Oleanolic acid and related derivatives as medicinally important compounds

Sultana

Ata

2008

Journal of Enzyme Inhibition and Medicinal Chemistry

182

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Oleanolic acid has been isolated from chloroform extract of Olea ferruginea Royle after removal of organic bases and free acids. The literature survey revealed it to be biologically very important. In this review the biological significance of oleanolic acid and its derivatives has been discussed. The aim of this review is to update current knowledge on oleanolic acid and its natural and semisynthetic analogs, focussing on its cytotoxic, antitumer, antioxidant, anti-inflamatory, anti-HIV, acetyl cholinesterase, alpha-glucosidase, antimicrobial, hepatoprotective, anti-inflammatory, antipruritic, spasmolytic activity, anti-angiogenic, antiallergic, antiviral and immunomodulatory activities. We present in this review, for the first time, a compilation of the most relevant scientific papers and technical reports of the chemical, pre-clinical and clinical research on the properties of oleanolic acid and its derivatives.

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Section: Anticomplement Activities Of Oleanolic Acid Monodesmosides Amentioning

confidence: 99%

Oleanolic acid and related derivatives as medicinally important compounds

Sultana

Ata

2008

Journal of Enzyme Inhibition and Medicinal Chemistry

182

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“…Compound 2 has been reported previously from the roots of Caulophyllum robustum Maxim [ 12 ], but its spectral data are reported here for the first time. Compounds 3 and 4 were identified as arjunolic acid and hederagenin, respectively, by a combination of spectroscopic methods and comparisons with the literature data [ 13 , 14 ].…”

Section: Resultsmentioning

confidence: 84%

Triterpenes from Stachyurus himalaicus var. himalaicus Hook. f. et Thoms. ex Benth

Wang

Huang

Li³

et al. 2010

Molecules

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Four triterpenes 1–4, including a new naturally occurring oleanane-type triterpene 1, were isolated by a multi-step chromatography procedure from the leaves and twigs of Stachyurus himalaicus var. himalaicus Hook. f. et Thoms.ex Benth. The structures of the compounds were elucidated by spectroscopic methods, including HRESIMS, 1H- NMR, 13C-NMR, DEPT, HMQC, HMBC and NOESY spectra. All the isolated compounds were evaluated for their in vitro cytotoxic activities against human Hela cell line.

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