Toxic anterior segment syndrome following EyePCL implantation in a hyperopic patient

Pintiliuc, C; Ricaud, Xavier; Costantini, E.

doi:10.1016/j.jfo.2021.12.009

Cited by 4 publications

(3 citation statements)

References 8 publications

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“…In our patient, the exact cause of TASS could not be ascertained. Although it has been frequently reported following cataract surgery, TASS following ICL-V4c has been reported in very few cases previously, and all cases were successfully managed with timely initiation of intense steroid therapy with none of them requiring pIOL explantation 11–13 17. It is important to identify and treat TASS with intensive steroid therapy as extensive anterior segment inflammation can result in grave sequelae such as toxic endothelial cell damage, corneal decompensation, secondary glaucoma, synechiae formation and cystoid macular oedema.…”

Section: Discussionmentioning

confidence: 99%

“…On another note, cataract was a concern with the original posterior chamber pIOLs, but its incidence has been significantly reduced, even to zero in some series, with newer models of the device. Other complications, such as postoperative pupillary block, toxic anterior segment syndrome (TASS) and Urrets-Zavalia syndrome, have been rarely reported following posterior chamber pIOL 7–15…”

Section: Introductionmentioning

confidence: 99%

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Complications following implantation of posterior chamber phakic intraocular lens (pIOL)

et al. 2022

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A male patient in his 20s presented with right eye aphakic corneal decompensation and left eye intumescent cataract with phakic intraocular lens (pIOL) lenticular touch. He had a history of pIOL implantation in both eyes 6 months ago. On first postoperative day, uncorrected distance visual acuity was 20/400 and 20/20 in right and left eye, respectively. Postoperatively, a diagnosis of right eye toxic anterior segment syndrome (TASS) was made and pIOL was explanted. Subsequently, the patient developed intumescent cataract for which lens aspiration with posterior chamber intraocular lens (PCIOL) implantation was performed in the right eye. Ongoing uveitis with membrane formation warranted PCIOL explantation. The patient developed aphakic corneal decompensation in the right eye and underwent penetrating keratoplasty with intrascleral haptic fixation of an intraocular lens. Central pIOL-lenticular touch with intumescent cataract was diagnosed in the left eye for which pIOL explant with lens aspiration and PCIOL was done. TASS and post-pIOL cataract are rare but vision-threatening complications require judicious management for visual rehabilitation.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Complications following implantation of posterior chamber phakic intraocular lens (pIOL)

et al. 2022

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“…Known major causes include preservatives in ophthalmic solutions, denatured viscoelastic substances, bacterial endotoxins, and inflammation induced by artificial intraocular lenses (38). Although ICL implantation surgery is less time-consuming and involves fewer steps, the entry of non-infectious toxic substances is difficult to avoid, and there have been occasional reports of TASS occurring after ICL implantation (39)(40)(41). TASS typically manifests acutely within 12 to 48 h postoperatively, with some cases exhibiting delayed reactions.…”

Section: Excessive Icl Vaultmentioning

confidence: 99%

Causes and management strategies for elevated intraocular pressure after implantable collamer lens implantation

Gong,

Deng,

Dang

et al. 2024

Front. Med.

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With the widespread application of Implantable Collamer Lens (ICL) implantation surgery in the field of myopia correction, a comprehensive understanding of its potential complications, especially those related to intraocular pressure (IOP), becomes crucial. This article systematically reviews various complications that may lead to IOP elevation after ICL surgery. Firstly, common complications after ICL surgery, including residual viscoelastic, steroid response, and excessive vault of the ICL, are detailed, emphasizing their potential impact on intraocular pressure. Regarding residual viscoelastic, we delve into its direct relationship with postoperative elevated IOP and possible preventive measures. For steroid response, we stress the importance of timely adjustment of steroid therapy and monitoring intraocular pressure. Additionally, excessive vault of the ICL is considered a significant potential issue, and we elaborate on its mechanism and possible management methods. In further discussion, we focus on relatively rare complications such as Toxic Anterior Segment Syndrome (TASS), Urrets-Zavalia Syndrome (UZS), Pigment Dispersion Syndrome (PDS), and malignant glaucoma. For these relatively rare complications, this review thoroughly explores their potential mechanisms, emphasizes the importance of prevention, and provides guidance for early diagnosis and treatment. This is a comprehensible review that aims to offer eye care professionals a comprehensive understanding and effective management guidance for complications of elevated IOP after ICL surgery, ultimately providing optimal care for patients’ visual health.

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Presumed atypical late-onset toxic anterior segment syndrome after implantable collamer lens implantation: a case report

Qi,

Xie,

Zhang

2024

BMC Ophthalmol

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Toxic anterior segment syndrome following EyePCL implantation in a hyperopic patient

Cited by 4 publications

References 8 publications

Complications following implantation of posterior chamber phakic intraocular lens (pIOL)

Complications following implantation of posterior chamber phakic intraocular lens (pIOL)

Causes and management strategies for elevated intraocular pressure after implantable collamer lens implantation

Presumed atypical late-onset toxic anterior segment syndrome after implantable collamer lens implantation: a case report

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