Towards the Commercialization of Hemoperfusion Column Part II. Coating of Activated Carbon

Erturk, E.; Haberal, Mehmet; Pi̇şki̇n, Erhan

doi:10.3109/10731198709117560

Cited by 4 publications

(5 citation statements)

References 12 publications

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“…antigens, antibodies, enzymes) are clinically applied [133]. Moreover, hemoperfusion has successfully been used to remove hypnotics and sedatives, analgetics, agricultural chemicals and cardiovascular agents.…”

Section: Membrane Module and Processmentioning

confidence: 99%

Medical applications of membranes: Drug delivery, artificial organs and tissue engineering

Stamatialis

Papenburg

Girones

et al. 2008

Journal of Membrane Science

414

236

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This paper covers the main medical applications of artificial membranes. Specific attention is given to drug delivery systems, artificial organs and tissue engineering which seem to dominate the interest of the membrane community this period. In all cases, the materials, methods and the current state of the art are evaluated and future prospects are discussed. Concerning drug delivery systems, attention is paid to diffusion controlled systems. For the transdermal delivery systems, passive as well as iontophoretic systems are described in more detail. Concerning artificial organs, we cover in detail: artificial kidney, membrane oxygenation, artificial liver, artificial pancreas as well as the application of membranes for tissue engineering scaffolds and bioreactors. This review shows the important role of membrane science and technology in medical applications but also highlights the importance of collaboration of membrane scientists with others (biologists, bioengineers, medical doctors, etc.

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Section: Membrane Module and Processmentioning

confidence: 99%

Medical applications of membranes: Drug delivery, artificial organs and tissue engineering

Stamatialis

Papenburg

Girones

et al. 2008

Journal of Membrane Science

414

236

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“…Other sorbents, for example various immunosorbents and more complex sorbent systems; incorporated with bio-functional agents (e.g. antigens, antibodies, enzymes) are utilized for clinical applications [91]. The pioneering work of Yatzidis [92] reported an effective removal of creatinine, uric acid, phenols, organic acids and barbiraturates by direct hemoperfusion through uncoated activated charcoal.…”

Section: Extracorporeal Blood Purificationmentioning

confidence: 99%

Mixed matrix membrane adsorbers for protein and blood purification

Saiful

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I express deeply my sincere gratitude to my research advisor, Dr.-Ing. Zandrie Borneman, for his encouragements, guidance and inspirations throughout this work, especially in the beginning of my study, for all his cares and all valuable discussions made the hard of a beginner PhD a little more manageable. I have exceedingly benefited from his vast knowledge, lasting enthusiasm and exceptional personality, but also for his friendship without which this dissertation would not be possible to be done. You are very supportive and give a freedom in doing the research. Zandrie, thank you very much for your input in the thesis: reading, correcting and improving the thesis. Many thank for translating the summary into the samenvatting. I am also indebt to other staff members of the group: Dimitris, Rob, Kitty and Antoine for nice and collegial research atmosphere with me.I would also like to thank the members of my promotion committee for reading the final draft of the thesis, giving approval to publicly defend this thesis and being part of this special day. It is an honour for me that Prof. Dr. J.F.J. Engbersen, Prof. Dr. J. Feijen and specially Prof. Ing. Giulio C. Sarti and Dr.-Ing. Bernd Krause (who will make such a long journey) can attend the promotion ceremony. I am also proud that two special people, Joào M. Sousa André de and M. Srivatsa Bettahalli Narasimha, can be my paranimfs and can accompany me in such important moment.A ton gratitude for all my friends for constantly supporting me and for making me feels at home when times are tough. Former members of my roommates: Nela, Kitty and Anna for many discussion and support during the initial phase of my PhD, made me confident during the in beginning of the project. It is not easy to work when my feeling depart to my family in Indonesia. Saskia, thank's a lot for sharing your knowledge and experiences about MMM in beginning of the project. I want to thank my new roommates: Miriam, Srivatsa, Magda, Katja and Clara with humor, joviality and kindness. No day without cookies and chocolate as well as a week of fruits. Special thanks are extended to Magda, the mother's of MMM, for her invaluable discussions and supports. Many thanks are owed to Joao for his helpful suggestions and continuous encouragement. Your inputs and corrections are really appreciated: muitíssimo agradecido. Spending one month in the new building Meander was very exciting. All are in new: new laboratory, new office and new roommates with new spirit. I would like to thank Szymon, Jorrit, and Schwan for nice talks and supports during the last month.It has not been completely easy and smooth for four years study in this country. I found a difficult time when the strong earth quake and tsunami disaster were hit and swap my hometowns where my beloved family and my parent are living. Fortunately, my family and my parent are safe. However, we are very sad and shock because my family and I were passed away for peace by some of close relatives and friends. Sadly approximately 173.741 people were died in my p...

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“…These work lead to the commercialization of polymer coatings (cellulose acetate, polyhydroxyethylmethacrylate, polyacrylic, etc) based activated carbon adsorbents [13]. However, current coating materials still could not fully eliminate the negative influence in hemoperfusion applications and therefore the development of novel polymer coatings with better performance is still highly desired [14,16].…”

Section: Introductionmentioning

confidence: 99%

“…Ideal coating materials for activated carbon must possess excellent blood compatibility without hemolysis, protein adsorption or coagulation, while should also be highly permeable to target toxins [16,25]. Recently, zwitterionic materials have received increasingly attention in many biomedical applications, attributed to their excellent "antifouling" properties to resist non-specific protein adsorption as well as cell or bacteria adhesion.…”

Section: Introductionmentioning

confidence: 99%

“…To solve this problem, Chang et al introduced a microencapsulation process that could cover the activated carbon particles with a polymeric coating [15]. In this way, the coating could directly contact with blood instead of bare activated carbon, thus the hemocompatibility and the hemoperfusion performance could be improved [16]. In the pioneering studies of Chang, a number of coating materials such as cellulose nitrate, albumin-collodion, cellulose acetate, and polyamide have been evaluated [17][18][19].…”

Section: Introductionmentioning

confidence: 99%

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Antifouling zwitterionic hydrogel coating improves hemocompatibility of activated carbon hemoadsorbent

Cai

Zhang

et al. 2017

Journal of Colloid and Interface Science

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Towards the Commercialization of Hemoperfusion Column Part II. Coating of Activated Carbon

Abstract: This paper reports the studies of coating of activated carbon. Spherical petroleum-based bead activated carbon with a size range of 0.4-1.0 mm was the adsorbent used in this study. These activated carbon granules were coated with cellulose nitrate of different thickness.

Cited by 4 publications

References 12 publications

Medical applications of membranes: Drug delivery, artificial organs and tissue engineering

Medical applications of membranes: Drug delivery, artificial organs and tissue engineering

Mixed matrix membrane adsorbers for protein and blood purification

Antifouling zwitterionic hydrogel coating improves hemocompatibility of activated carbon hemoadsorbent

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