Towards the Clinical Implementation of Extracellular Vesicle-Based Biomarker Assays for Cancer
Sofie Van Dorpe,
Philippe Tummers,
Hannelore Denys
et al.
Abstract:Background
Substantial research has been devoted to elucidating the role of extracellular vesicles (EVs) in the different hallmarks of cancer. Consequently, EVs are increasingly explored as a source of cancer biomarkers in body fluids. However, the heterogeneity in EVs, the complexity of body fluids, and the diversity in methods available for EV analysis, challenge the development and translation of EV-based biomarker assays.
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