Abstract:Background. There is no ideal substitute for the extracellular matrix (ECM) in tissue engineering. We aim to develop peptide‐based fibrous and hydrogel materials as potential scaffolds for 2‐/3‐D culture in vitro and in vivo.
Methods. Unlike other peptide scaffolds, we employed a system using α‐helical units with two complementary peptides, which combine to yield a sticky ended building block for fibre assembly (self‐assembly fibres, SAFs). This allows control over assembly, and brings utility as either pept… Show more
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