Towards enhancing the user experience of ChIP-Seq data analysis web tools

Abstract

<p>Deoxyribonucleic acid (DNA) sequencing is the process of locating the sequence of the main chemical bases in the DNA. Next-generation sequencing (NGS) is the state-of-the-art DNA sequencing technique. The NGS technique advanced the biological science in analyzing human DNA due to its scalability, high throughput, and speed. Analyzing human DNA is crucial to determine the ability of a person to develop certain diseases and his ability to respond to certain medications. ChIP-sequencing is a method that combines chromatin immunoprecipitation (ChIP) with NGS sequencing to analyze protein interactions with DNA to identify binding sites. Many online web tools have been developed to conduct ChIP-Seq data analysis to either discover or find motifs, i.e., patterns of binding sites. Since these ChIP-Seq web tools need to be used by clinical practitioners, they must comply to the web-related usability tasks including effectiveness, efficiency and satisfaction to enhance the user experience (UX). To that end, we have conducted an empirical study to understand their UX design. Specifically, we have evaluated the usability of 8 widely used ChIP-Seq web tools against 6 known usability quality metrics. Our study shows that the design of the studied ChIP-Seq web tools does not follow the UX design principles.</p>

Interface design features and evaluation of batik 4.0 mobile application

“…The investigation of user-centered design (UCD) principles and usability guidelines can improve the use of and satisfaction on the design of mobile apps has been investigated in several sectors. Some of time-critical weather alert apps [7], investigate the UI design principles of mobile Al-Quran apps for senior citizens [8], the design and usability quality metrics evaluation of chromatin immunoprecipitation combined with sequencing (ChIP-seq) web tools [9], a new prototype design for a smartwatch UI [10], the development of a mobile-based UI that makes it easier for farmers to view the data [11], redesigning food delivery application [12], and development of Marine tourism [13]. In the education sector [14] [16], among others design and development of a simple content management system for learning called the EMasters [17], PAUD monitoring application [18].…”