Towards a judicious use of perilesional biopsy in the era of MRI-targeting, parting of the ways from systematic prostate biopsy

Index lesion contouring on prostate MRI for targeted MRI/US fusion biopsy – Evaluation of mismatch between radiologists and urologists

“…There are several reasons why MTB in men with positive MRI may fail to detect clinically significant prostate cancers, which are picked up by concurrent or subsequent systematic biopsy [20,21]. Sources of errors associated with the MTB procedure itself include MRI-US misregistration, operator experience, the biopsy method itself and issues with lesion delineation leading to a mismatch between the planned target and the actual biopsy landing zone [21,22].…”