Towards a Central-Eastern European EQ-5D-3L population norm: comparing data from Hungarian, Polish and Slovenian population studies

Zrubka, Zsombor; Golicki, Dominik; Rupel, Valentina Prevolnik; Baji, Petra; Rencz, Fanni; Brodszky, Valentin; Gulàcsi, László; Péntek, Márta

doi:10.1007/s10198-019-01071-0

Cited by 15 publications

(7 citation statements)

References 23 publications

(31 reference statements)

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“…They concluded that between the four European countries, there is less variance than between value sets of Western and non-Western value sets [ 36 ]. Another study compared three EQ-5D valuations in Central and Eastern European countries and further estimated a population norm for this region [ 37 ]. These studies thus suggest that a pooled value set depicting averaged European health state values may indeed be a feasible and sensible way forward in health economics research.…”

Section: Discussionmentioning

confidence: 99%

In search of a ‘pan-European value set’; application for EQ-5D-3L

Sajjad

Versteegh

Santi

et al. 2023

BMC Med Res Methodol

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Objectives Country-specific value sets for the EQ-5D are available which reflect preferences for health states elicited from the general population. This allows the transformation of responses on EQ-5D to health state utility values. Only twelve European countries possess country-specific value sets and no value set reflecting the preferences of Europe exists. We aim to estimate a ‘pan-European’ value set for the EQ-5D-3L, reflecting the preferences for health states of the European population that could help to evaluate health care from the perspective of the European decision-maker. Methods We systematically assessed and compared the methodologies of available EQ-5D-3L time trade-off (TTO) value sets from twelve European countries: Denmark, France, Germany, Hungary, Italy, Netherlands, Poland, Portugal, Romania, Slovenia, Spain and UK. Using their published coefficients, a dataset with utility values for all 243 health states was simulated. Different modelling techniques and model specifications including interaction terms were tested. Model selection was based on goodness-of-fit criteria. We also explored results with application of population size weights. Results Methodological, procedural and analytical characteristics of the included EQ-5D-3L valuation studies were quite comparable. An OLS based model was the preferred model to represent European preferences. Weighting with population size made little difference. Conclusions EQ-5D-3L valuation studies were considered of sufficient comparability to form the basis for a new ‘pan-European’ value set. The method used allows for an easy update when new national value sets become available.

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Section: Discussionmentioning

confidence: 99%

In search of a ‘pan-European value set’; application for EQ-5D-3L

Sajjad

Versteegh

Santi

et al. 2023

BMC Med Res Methodol

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“…The comparison of Slovenian population norms with population norms in EU countries, specifically, in Central and Eastern European countries, showed that in all dimensions, problems were reported most frequently by Slovenian, followed by Polish and Hungarian respondents. 33 Because education was found to significantly influence the occurrence of health problems in all dimensions of the EQ-5D-3L and a lower-education population was overrepresented in Slovenian sample, the issue should be further explored.…”

Section: Discussionmentioning

confidence: 99%

Comparing Quality of Life of General Population and Orthopedic Patients in Slovenia

Rupel

Slabe‐Erker

Divjak

2020

Value in Health Regional Issues

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To our knowledge this is the first study presenting descriptive EQ-5D health profile and VAS scores for orthopedic patients in Slovenia. Furthermore, EQ-5D-3L population norms for Slovenia are presented. The aims of this study are (1) to provide population norms for EQ-5D-3L in Slovenia according to age and sex and (2) to compare different groups of orthopaedic patients' health state among themselves as well as to the general population.Methods: Data on orthopedic patients' preoperative health status assessment were recorded (n = 1118). The health status of 4 groups of orthopedic patients was analyzed and compared using EQ VAS and the EQ-5D descriptive profile. The results were compared with Slovenian population norms, which were calculated using the EQ-5D valuation set database from year 2000 (n = 708).Results: As expected, a higher proportion of patients than the general population report problems on all dimensions. The opposite is true only for mobility and anxiety/depression dimension for shoulder surgery patients. Hip endoscopy patients have the lowest health-related quality of life (HRQoL) out of all patient groups using EQ VAS and EQ-5D descriptive profiles. Conclusion:The population norms presented will be useful for many researchers trying to compare HRQoL among various patient groups or the general population. Separate use of the descriptive profile of the EQ-5D is informative when assessing HRQoL in orthopedic patients and is in line with VAS values. The results can support further studies on health needs assessment as well as decisions on funds allocation among groups of orthopedic patients.

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“…Value sets are generated for specific populations and numerous sets are available for different country societies from 6 continents [ 28 ]. Local preferences may vary between and within countries and may be influenced by age, gender, standard of living, health expenditure or unemployment [ 34 , 35 ]. For countries without regional scores, estimated regional population norms can be used; an algorithm has also been developed to map responses from the EQ-5D-3L to the scores of the newer, more sensitive 5-level questionnaire (EQ-5D-5L) [ 35 , 36 ].…”

Section: Methodsmentioning

confidence: 99%

The Estimate of Parental Quality of Life Loss Due to Respiratory Syncytial Virus (RSV) Hospitalization

Wrotek,

Jackowska

2023

Diseases

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Background: Respiratory syncytial virus (RSV) is one of the leading causes of pediatric hospitalizations, mainly in children under 2 years of age. Hospitalization affects the caregivers’ quality of life (QoL). We assessed the caregivers’ QoL during RSV-confirmed hospitalizations of children under 2 years old, identified the most affected QoL dimensions and calculated utilities focusing on the assessment methods and potential confounders. Methods: The caregivers filled out the EQ-5D questionnaire, consisting of a descriptive system (assessing 5 QoL dimensions) and a visual analog scale (EQ VAS). Utility, utility loss and quality-adjusted life years (QALY) loss were calculated, and a concordance between the two systems was assessed. Results: A disturbance in any of the five assessed dimensions was reported by 42% (55 out of 132) of the caregivers, mostly anxiety/depression (37%) and pain/discomfort (17%). The utilities varied between 0.17 and 1 in the descriptive system and 0.33–1 (median 0.86) in the EQ VAS, with a utility loss of 0.14 (IQR: 0.1–0.2). The calculated QALY loss reached a median of 2.45 × 10−3 (IQR: 1.37 × 10−3–4.56 × 10−3) and was not influenced by the patient’s age or the final clinical diagnosis (QALY loss for bronchiolitis: 2.74 × 10−3, pneumonia: 1.84 × 10−3, bronchitis: 1.78 × 10−3, differences statistically insignificant). Only a moderate concordance between the descriptive system and the EQ VAS was seen (Spearman’s rank correlation coefficient = 0.437, p < 0.05), with the latter revealing a higher degree of QoL disturbances. Conclusions: RSV hospitalization influences parental QoL significantly, and anxiety/depression is the most commonly reported issue. Utility impairment scores depend on the assessment method but not on the patient’s age or final diagnosis. Thus, the impact of RSV on caregivers’ QoL cannot be underestimated.

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Towards a Central-Eastern European EQ-5D-3L population norm: comparing data from Hungarian, Polish and Slovenian population studies

Cited by 15 publications

References 23 publications

In search of a ‘pan-European value set’; application for EQ-5D-3L

In search of a ‘pan-European value set’; application for EQ-5D-3L

Comparing Quality of Life of General Population and Orthopedic Patients in Slovenia

The Estimate of Parental Quality of Life Loss Due to Respiratory Syncytial Virus (RSV) Hospitalization

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