Toward osteomimetic formation of calcium phosphate coatings with carbonated hydroxyapatite

Idaszek, Joanna; Jaroszewicz, Joanna; Choińska, Emilia; Górecka, Żaneta; Hyc, Anna; Osiecka-Iwan, Anna; Wielunska-Kuś, Barbara; Święszkowski, Wojciech; Moskalewski, Stanisław

doi:10.1016/j.bioadv.2023.213403

Cited by 5 publications

(3 citation statements)

References 56 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, that method from 2019 did not contain HCO 3 − ions in the media. In 2023, the same authors added HCO 3 − ions to the phosphatase incubation medium and called it "osteomimetic deposition" [799]. The addition of NaHCO 3 to the incubation medium produced A and B types of carbonate substituted CDHA.…”

Section: Osteomimetic Depositionmentioning

confidence: 99%

See 1 more Smart Citation

There Are over 60 Ways to Produce Biocompatible Calcium Orthophosphate (CaPO4) Deposits on Various Substrates

Dorozhkin

2023

J. Compos. Sci.

View full text Add to dashboard Cite

A The present overview describes various production techniques for biocompatible calcium orthophosphate (abbreviated as CaPO4) deposits (coatings, films and layers) on the surfaces of various types of substrates to impart the biocompatible properties for artificial bone grafts. Since, after being implanted, the grafts always interact with the surrounding biological tissues at the interfaces, their surface properties are considered critical to clinical success. Due to the limited number of materials that can be tolerated in vivo, a new specialty of surface engineering has been developed to desirably modify any unacceptable material surface characteristics while maintaining the useful bulk performance. In 1975, the development of this approach led to the emergence of a special class of artificial bone grafts, in which various mechanically stable (and thus suitable for load-bearing applications) implantable biomaterials and artificial devices were coated with CaPO4. Since then, more than 7500 papers have been published on this subject and more than 500 new publications are added annually. In this review, a comprehensive analysis of the available literature has been performed with the main goal of finding as many deposition techniques as possible and more than 60 methods (double that if all known modifications are counted) for producing CaPO4 deposits on various substrates have been systematically described. Thus, besides the introduction, general knowledge and terminology, this review consists of two unequal parts. The first (bigger) part is a comprehensive summary of the known CaPO4 deposition techniques both currently used and discontinued/underdeveloped ones with brief descriptions of their major physical and chemical principles coupled with the key process parameters (when possible) to inform readers of their existence and remind them of the unused ones. The second (smaller) part includes fleeting essays on the most important properties and current biomedical applications of the CaPO4 deposits with an indication of possible future developments.

show abstract

Section: Osteomimetic Depositionmentioning

confidence: 99%

“…The authors concluded that "After further development, osteomimetic method will enable studies on the influence of bone specific phosphatases and various phosphorylated substrates on the HAP crystals formation and their deposition on the artificial scaffolds or collagen fibrils" (Ref. [799], p. 12).…”

Section: Osteomimetic Depositionmentioning

confidence: 99%

There Are over 60 Ways to Produce Biocompatible Calcium Orthophosphate (CaPO4) Deposits on Various Substrates

Dorozhkin

2023

J. Compos. Sci.

View full text Add to dashboard Cite

show abstract

“…Compared to conventional calcium phosphate-based graft materials, calcium phosphate nanomaterials offer several distinct advantages and show unique properties for bone tissue engineering, including enhanced bioactivity, tailored physical and chemical properties, controlled drug delivery, better integration with host tissue, and ease of fabrication and scalability. Specifically, these biomaterials have a high surface area to volume ratio, which provides more space for cell adhesion and proliferation and also promotes cell differentiation [ 11 , 12 ], as well as loading more therapeutic ingredients [ 13 , 14 ]. Additionally, the nano-sized particles can enhance the mechanical properties and show a profile of controlled drug release.…”

Section: Introductionmentioning

confidence: 99%

Calcium Phosphate-Based Nanomaterials: Preparation, Multifunction, and Application for Bone Tissue Engineering

Chen

et al. 2023

Molecules

View full text Add to dashboard Cite

Calcium phosphate is the main inorganic component of bone. Calcium phosphate-based biomaterials have demonstrated great potential in bone tissue engineering due to their superior biocompatibility, pH-responsive degradability, excellent osteoinductivity, and similar components to bone. Calcium phosphate nanomaterials have gained more and more attention for their enhanced bioactivity and better integration with host tissues. Additionally, they can also be easily functionalized with metal ions, bioactive molecules/proteins, as well as therapeutic drugs; thus, calcium phosphate-based biomaterials have been widely used in many other fields, such as drug delivery, cancer therapy, and as nanoprobes in bioimaging. Thus, the preparation methods of calcium phosphate nanomaterials were systematically reviewed, and the multifunction strategies of calcium phosphate-based biomaterials have also been comprehensively summarized. Finally, the applications and perspectives of functionalized calcium phosphate biomaterials in bone tissue engineering, including bone defect repair, bone regeneration, and drug delivery, were illustrated and discussed by presenting typical examples.

show abstract

Strontium-calcium doped titanium dioxide nanotubes loaded with GL13K for promotion of antibacterial activity, anti-Inflammation, and vascularized bone regeneration

Jia,

Xu,

Sun

et al. 2023

Ceramics International

View full text Add to dashboard Cite

Toward osteomimetic formation of calcium phosphate coatings with carbonated hydroxyapatite

Cited by 5 publications

References 56 publications

There Are over 60 Ways to Produce Biocompatible Calcium Orthophosphate (CaPO4) Deposits on Various Substrates

There Are over 60 Ways to Produce Biocompatible Calcium Orthophosphate (CaPO4) Deposits on Various Substrates

Calcium Phosphate-Based Nanomaterials: Preparation, Multifunction, and Application for Bone Tissue Engineering

Strontium-calcium doped titanium dioxide nanotubes loaded with GL13K for promotion of antibacterial activity, anti-Inflammation, and vascularized bone regeneration

Contact Info

Product

Resources

About