Toward Hepatitis C Elimination in Marginalized Populations by a Collaborative Multi-Setting Approach in Taiwan

Su, Wei‐Wen; Yang, Chih‐Chao; Chang, Wei-Jung; Yeh, Yung‐Hsiang; Yen, Hsu‐Heng; Yang, Chi‐Chieh; Lee, Yu-Lin; Liu, Chun-Eng; Liang, Sun-Yuan; Sung, Man-Li; Ko, Shu-Yu; Kuo, Chung-Yang; Chen, Sam Li Sheng; Yeh, Yen-Po; Hu, Tsung–Hui

doi:10.2139/ssrn.4022233

Cited by 2 publications

(4 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This systematic collaboration strategy of CHIPS-C was also applied to people living with HIV, people who inject drugs, and incarcerated individuals, yielding equivalent results that have been published in full elsewhere (12). Such community-based HCV care may have the potential to be advantageous, both operationally and economically, for both moderate-risk people such as DM and high-risk vulnerable groups.…”

Section: Discussionmentioning

confidence: 97%

“…Nevertheless, despite efforts to screen and treat, multiple barriers have slowed HCV care continuum progress in many HCV-affected populations (1,(5)(6)(7)(8). Numerous studies have concluded that a major challenge in overcoming these barriers involves the integration of HCV care into existing healthcare programs serving people at high risk of HCV infection (5)(6)(7)(8)(9)(10)(11)(12)(13), such as the successful collaboration of HCV care with HIV specialty care (10,12) and prison health services (11,12).…”

Section: Introductionmentioning

confidence: 99%

“…To achieve HCV elimination for people living in Changhua, Taiwan, an integrated care model dubbed the Changhua Integrated Program to Stop HCV Infection (CHIPS-C) was developed in a phase-in, cross-sectoral, multi-institution collaboration approach (12,13,20). It began with the elimination of HCV in 2 major disadvantaged at-risk subpopulations, including the dialysis population and the PWID group, as described in the previous reports (Figure 1) (12,13). The CHIPS-C was further extended to a cohort of patients with diabetes (PwD) in primary care settings, which is the focus of this study.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Using the Diabetes Care System for a County-Wide Hepatitis C Elimination: An Integrated Community-Based Shared Care Model in Taiwan

Hu,

Luh,

Tsao

et al. 2024

Am J Gastroenterol

Self Cite

View full text Add to dashboard Cite

Introduction: Despite the serious risks of diabetes with HCV infection, this preventable comorbidity is rarely a priority for HCV elimination. We aim to examine how a shared care model could eliminate HCV in patients with diabetes (PwD) in primary care. Methods: There were 27 community-based Diabetes Health Promotion Institutes in each township/city of Changhua, Taiwan. PwD from these institutes from January, 2018, to December, 2020 were enrolled. HCV screening and treatment were integrated into diabetes structured care through collaboration between diabetes care and HCV care teams. Outcome measures included HCV care continuum indicators. Township/city variation in HCV infection prevalence and care cascades were also examined. Results: Of the 10,684 eligible PwD, 9984 (93.4%) underwent HCV screening, revealing a 6.18% (n = 617) anti-HCV seroprevalence. Among the 597 eligible seropositive individuals, 507 (84.9%) completed the RNA test, obtaining 71.8% positives. Treatment was initiated by 327 (89.8%) of 364 viremic patients, and 315 (86.5%) completed it, resulting in a final cure rate of 79.4% (n = 289). Overall, with the introduction of antivirals in this cohort, the prevalence of viremic HCV infection dropped from 4.44% to 1.34%, yielding a 69.70% (95% CI: 63.64%-77.03%) absolute reduction. Discussion: Although HCV prevalence varied, the care cascades achieved consistent results across townships/cities. We have further successfully implemented the model in county-wide hospital-based diabetes clinics, eventually treating 89.6% of the total PwD. A collaborative effort between diabetes care and HCV elimination enhanced the testing and treatment in PwD through an innovative shared care model.

show abstract

Section: Discussionmentioning

confidence: 97%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Using the Diabetes Care System for a County-Wide Hepatitis C Elimination: An Integrated Community-Based Shared Care Model in Taiwan

Hu,

Luh,

Tsao

et al. 2024

Am J Gastroenterol

Self Cite

View full text Add to dashboard Cite

show abstract

“…Several studies have reported good effectiveness of HCV treatment in these institutions (Table 1). 14,[50][51][52] Prisoners are at high risk for HCV infection. Treating PWID in prisons represents an optimal time for access to DAAs and is cost effective.…”

Section: Barriers and Interventions For Hcv Micro-elimination In Pwidmentioning

confidence: 99%

Hepatitis C virus micro‐elimination in people who inject drugs: Challenges and chance in Taiwan and worldwide

Tai,

2023

The Kaohsiung J of Med Scie

View full text Add to dashboard Cite

With the introduction of direct‐acting antivirals, elimination of hepatitis C virus (HCV) infection is becoming possible. People who inject drugs (PWID) represent a population with a high risk for HCV infection, which has been reported as high as 90% in Taiwanese PWID. To reach the goal of HCV elimination, PWID is a key population deserving special attention. Barriers in HCV care cascade still exist in PWID, and interventions to promote access to HCV diagnosis, link‐to‐care, treatment, and prevention for PWID are warranted. Although HCV micro‐elimination can be achieved in some prisons and opioid substitution therapy (OST) centers by a multidisciplinary team and integrated care in Taiwan, there are still several unmet needs for HCV elimination in PWID. Continuous efforts, such as the participation of OST specialists and the continuum of care for HCV among PWID, are needed to achieve HCV elimination in Taiwan. In addition, the combination of harm reduction services, treatment as prevention and regular posttreatment HCV surveillance is critical to substantially reduce HCV transmission and prevalence in PWID.

show abstract

Toward Hepatitis C Elimination in Marginalized Populations by a Collaborative Multi-Setting Approach in Taiwan

Cited by 2 publications

References 0 publications

Using the Diabetes Care System for a County-Wide Hepatitis C Elimination: An Integrated Community-Based Shared Care Model in Taiwan

Using the Diabetes Care System for a County-Wide Hepatitis C Elimination: An Integrated Community-Based Shared Care Model in Taiwan

Hepatitis C virus micro‐elimination in people who inject drugs: Challenges and chance in Taiwan and worldwide

Contact Info

Product

Resources

About