Toward an individualized determination of dialysis adequacy: a narrative review with special emphasis on incremental hemodialysis

Torreggiani, Massimo; Fois, Antioco; Njandjo, Linda; Longhitano, Elisa; Chatrenet, Antoine; Esposito, Ciro; Fessi, H.; Piccoli, Giorgina Barbara

doi:10.1080/14737159.2021.1987216

Cited by 8 publications

(5 citation statements)

References 246 publications

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“…The choice of medications, dosages, and timing is guided by factors such as the severity of LPD, the patient's medical history, and the specifics of the treatment plan. This customization ensures that the therapy aligns perfectly with the patient's needs, optimizing the chances of achieving a successful pregnancy [ 64 ].…”

Section: Reviewmentioning

confidence: 99%

The Role of Dydrogesterone in the Management of Luteal Phase Defect: A Comprehensive Review

Muneeba,

Acharya,

Mohammad

2023

Cureus

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The luteal phase of the menstrual cycle is a pivotal period characterized by hormonal intricacies that lay the foundation for successful embryo implantation and early pregnancy development. Luteal phase defect (LPD), marked by abnormalities in luteal function, presents challenges that can impede reproductive outcomes. This comprehensive review article explores the role of dydrogesterone in LPD management, elucidating its mechanisms of action, evidence of efficacy, safety profile, and potential in combination therapies. Dydrogesterone, a synthetic progestogen, closely mirrors natural progesterone's actions, effectively supplementing the luteal phase and enhancing endometrial receptivity. Clinical studies demonstrate improved pregnancy rates, extended luteal phase support, and enhanced reproductive outcomes with dydrogesterone supplementation. Its favorable safety profile, minimal side effects, and reduced risk of unwanted hormonal effects contribute to its appeal. Furthermore, dydrogesterone's inclusion in international guidelines solidifies its importance in LPD management. Combination therapies, leveraging synergistic effects, offer a comprehensive approach. As gaps in knowledge persist, future research directions and personalized treatment strategies pave the way for a future where dydrogesterone stands as a beacon of hope in conquering the challenges of LPD and achieving successful reproductive outcomes.

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Section: Reviewmentioning

confidence: 99%

The Role of Dydrogesterone in the Management of Luteal Phase Defect: A Comprehensive Review

Muneeba,

Acharya,

Mohammad

2023

Cureus

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“…Liver disorders were listed as reasons for hypoalbuminemia dominating among the miscellaneous factors [33,62,64,65,105,141,163,164], with two liver disorder indices, ALBI and NFS, showing the greatest level of prevalence. The reasons for hypoalbuminemia among the miscellaneous factors (other than liver disorders) were acidosis [105], PA loss in dialysis [136], and nephrosis [141].…”

Section: Prognostic Indices Mainly Related To Specific Disorders: Rev...mentioning

confidence: 99%

Interpretations of the Role of Plasma Albumin in Prognostic Indices: A Literature Review

Gradel

2023

JCM

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This review assesses how publications interpret factors that influence the serum or plasma albumin (PA) level in prognostic indices, focusing on inflammation and nutrition. On PubMed, a search for “albumin AND prognosis” yielded 23,919 results. From these records, prognostic indices were retrieved, and their names were used as search strings on PubMed. Indices found in 10 or more original research articles were included. The same search strings, restricted to “Review” or “Systematic review”, retrieved yielded on the indices. The data comprised the 10 latest original research articles and up to 10 of the latest reviews. Thirty indices had 294 original research articles (6 covering two indices) and 131 reviews, most of which were from recent years. A total of 106 articles related the PA level to inflammation, and 136 related the PA level to nutrition. For the reviews, the equivalent numbers were 54 and 65. In conclusion, more publications mention the PA level as a marker of nutrition rather than inflammation. This is in contrast to several general reviews on albumin and nutritional guidelines, which state that the PA level is a marker of inflammation but not nutrition. Hypoalbuminemia should prompt clinicians to focus on the inflammatory aspects in their patients.

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“…Further benefits arising from RRF preservation are decreased systemic blood pressure [143,144], reduced left ventricular hypertrophy [145][146][147], increased sodium removal [148][149][150], improved fluid balance [149,151,152], lower serum b2-microglobulin levels [153][154][155], better nutritional status [156][157][158], and lower circulating inflammatory markers [159][160][161][162]. Additionally, RRF facilitates the achievement of adequacy targets [126,[163][164][165][166] and may contribute to controlling serum phosphate, uric acid, bicarbonate, and cholesterol levels [161,167,168]. An association between RRF and DGF rate has been established [112,113].…”

Section: Residual Renal Function At the Time Of Transplantmentioning

confidence: 99%

Peritoneal Dialysis for Potential Kidney Transplant Recipients: Pride or Prejudice?

et al. 2022

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Kidney transplantation (KT) is recognized as the gold-standard of treatment for patients with end-stage renal disease. Additionally, it has been demonstrated that receiving a pre-emptive KT ensures the best recipient and graft survivals. However, due to an overwhelming discrepancy between the organs available and the patients on the transplant waiting list, the vast majority of transplant candidates require prolonged periods of dialysis before being transplanted. For many years, peritoneal dialysis (PD) and hemodialysis (HD) have been considered competitive renal replacement therapies (RRT). This dualistic vision has recently been questioned by evidence suggesting that an individualized and flexible approach may be more appropriate. In fact, tailored and cleverly planned changes between different RRT modalities, according to the patient’s needs and characteristics, are often needed in order to achieve the best results. While home HD is still under scrutiny in this particular setting, current data seems to favor the use of PD over in-center HD in patients awaiting a KT. In this specific population, the demonstrated advantages of PD are superior quality of life, longer preservation of residual renal function, lower incidence of delayed graft function, better recipient survival, and reduced cost.

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Toward an individualized determination of dialysis adequacy: a narrative review with special emphasis on incremental hemodialysis

Cited by 8 publications

References 246 publications

The Role of Dydrogesterone in the Management of Luteal Phase Defect: A Comprehensive Review

The Role of Dydrogesterone in the Management of Luteal Phase Defect: A Comprehensive Review

Interpretations of the Role of Plasma Albumin in Prognostic Indices: A Literature Review

Peritoneal Dialysis for Potential Kidney Transplant Recipients: Pride or Prejudice?

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