Toward a Sustainable Blood Supply in the United States: An Analysis of the Current System and Alternatives for the Future

Mulcahy, Andrew W.; Kapinos, Kandice A.; Briscombe, Brian; Uscher‐Pines, Lori; Chaturvedi, Ritika; Case, Spencer R.; Hlávka, Jakub P.; Miller, Benjamin M.

doi:10.7249/rr1575

Cited by 24 publications

(36 citation statements)

References 20 publications

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“…Items used to measure MPS were adapted from the questions designed by (Hosseinifard & Abbasi, 2018;Mansur et al, 2019). Mulcahy et al (2017) suggested criteria was used to develop BTS questionnaire items. MPS was measured using a two-item scale.…”

Section: Methodsmentioning

confidence: 99%

“…Blood transfusion is necessary in addressing any blood shortages, illnesses and disorders in the human body (Lestari et al, 2017;Seed et al, 2018). As such, sustainable blood transfusion remains crucial in extending and improving life for many patients (Mulcahy et al, 2017;Kruk et al, 2018). Developing countries using voluntary non-remunerated donors (VNRDs) are encouraged to pursue strategies that focus on safety, full range, timely delivery and hospital best use of blood products (Kajja, 2013;Jenny et al, 2017;Williamson & Devine, 2013).…”

Section: Introductionmentioning

confidence: 99%

“…Blood banks need to understand how MPS could affect BTS (Alfonso & Xiaolan, 2015;Jonsson & Kjellsdotter, 2015;Dutta, 2019;Hosseinifard & Abbasi, 2018;Filho et al, 2013). Blood banks are expected to adapt to the environment and find unique avenues to optimize use of blood products and services (Mulcahy et al, 2017;Sibinga, 2017;Barro et al, 2018;WHO, 2011;Bloch et al, 2020). To improve the results of their businesses, managers have dedicated themselves to identifying program factors that influence performance and how to use them.…”

Section: Introductionmentioning

confidence: 99%

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The mediation effect of total quality management on the relationship between master production schedul-ing and blood transfusion sustainability in Uganda

Kaconco¹,

Nabuuma²,

Mugarura³

2023

10.5267/j.msl

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This paper seeks to examine the relationship between determinants of blood transfusion sustainability (BTS) that is master production scheduling (MPS) and total quality management (TQM) of Uganda. The study was founded on four objectives. The study looked at the direct relationship between MPS and the BTS, direct relationship between MPS and TQM, direct relationship between TQM and BTS. It also assessed how TQM mediated the direct relationship between MPS and BTS. The study used a quantitative method. A survey questionnaire was administered to collect data from 367 staff of regional blood banks and government university teaching hospital blood banks; and 213 were found to be usable. The main analysis was done using structural equation modeling. The study found that MPS had a positive and significant relationship with the BTS. The study found that the relationship between MPS and TQM was positive and significant. The study also found that the relationship between TQM and BTS was positive and significant. The study concluded that the effect of MPS on BTS was not mediated by TQM. It was recommended that blood banks seeking to achieve transfusion sustainability must invest in understanding the sector in which they operate. This includes understanding the blood demand requirement, customer focus, people involvement and timely delivery. The various stakeholders in the blood supply chain i.e. blood banks, hospital blood banks, funding agents, ministry of health, must also integrate to enhance the transfusion sustainability. Blood banks performance measures essentially timely delivery was very critical for saving lives of patients in need of blood. The study has provided a new conceptual framework that investigates the TQM mediating effect on the relationship of MPS and BTS, and thus can serve as an incentive for more research to be conducted in this regard in blood banks of different developing countries. The authors also proposed identifying the effect of other TQM factors such as process management, system management, supplier relationship and top management on BTS.

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Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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The mediation effect of total quality management on the relationship between master production schedul-ing and blood transfusion sustainability in Uganda

Kaconco¹,

Nabuuma²,

Mugarura³

2023

10.5267/j.msl

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“…14 These multiple sources of strain on transfusion services could lead to potentially preventable death during an MCI. 15,19 Although historically, the supply in U.S. hospitals and blood centers has typically been sufficient to cover the immediate demand following a terrorist attack, 20 careful analysis of the current blood inventory practices in major U.S. cities to enable the application of DCR principles during an MCI has not been performed, the adequacy of plasma and platelet inventories in these historic events remains uncertain, and the number of potentially preventable deaths from hemorrhage is unknown. 21 With this study conducted by the Trauma Hemostasis and Oxygenation Research Network (THOR)-Association for the Advancement of Blood and Biotherapies (AABB) working party, 22 we sought to prospectively analyze city-wide blood inventories in select major cities to evaluate their readiness to meet resuscitation standards during a major MCI.…”

Section: Introductionmentioning

confidence: 99%

U.S. cities will not meet blood product resuscitation standards during major mass casualty incidents: Results of a THOR‐AABB working party prospective analysis

et al. 2022

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Background Mass casualty incidents (MCIs) create an immediate surge in blood product demand. We hypothesize local inventories in major U.S. cities would not meet this demand. Study Design and Methods A simulated blast in a large crowd estimated casualty numbers. Ideal resuscitation was defined as equal amounts of red blood cells (RBCs), plasma, platelets, and cryoprecipitate. Inventory was prospectively collected from six major U.S. cities at six time points between January and July 2019. City‐wide blood inventories were classified as READY (>1 U/injured survivor), DEFICIENT (<10 U/severely injured survivor), or RISK (between READY and DEFICIENT), before and after resupply from local distribution centers (DC), and features of DEFICIENT cities were identified. Results The simulated blast resulted in 2218 injured survivors including 95 with severe injuries. Balanced resuscitation would require between 950 and 2218 units each RBC, plasma, platelets and cryoprecipitate. Inventories in 88 hospitals/health systems and 10 DCs were assessed. Of 36 city‐wide surveys, RISK inventories included RBCs (n = 16; 44%), plasma (n = 24; 67%), platelets (n = 6; 17%), and cryoprecipitate (n = 22; 61%) while DEFICIENT inventories included platelets (n = 30; 83%) and cryoprecipitate (n = 12; 33%). Resupply shifted most RBC and plasma inventories to READY, but some platelet and cryoprecipitate inventories remained at RISK (n = 24; 67% and n = 12; 33%, respectively) or even DEFICIENT (n = 11; 31% and n = 6; 17%, respectively). Cities with DEFICIENT inventories were smaller (p <.001) with fewer blood products per trauma bed (p <.001). Discussion In this simulated blast event, blood product demand exceeded local supply in some major U.S. cities. Options for closing this gap should be explored to optimize resuscitation during MCIs.

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“…Blood transfusion is necessary in addressing any blood shortages, illnesses and disorders in the human body (Lestari et al, 2017;Seed et al, 2018). As such, sustainable blood transfusion remains crucial in extending and improving life for many patients (Kruk et al, 2018;Mulcahy et al, 2017). Developing countries using voluntary non-remunerated donors (VNRDs) are encouraged to pursue strategies that focus on safety, full range, timely delivery and hospital best use of blood products (Jenny et al, 2017;Kajja, 2013;Williamson & Devine, 2013).…”

Section: Introductionmentioning

confidence: 99%

The mediation effect of blood production on the relationship between master production scheduling and transfusion sustainability in Uganda

2022

View full text Add to dashboard Cite

Background: This paper examines the relationship between determinants of blood transfusion sustainability (BTS) that is master production scheduling (MPS) and blood production (BP) of Uganda. The study was founded on four objectives. The study looked at the direct relationship between MPS and the BTS, direct relationship between MPS and BP, direct relationship between BP and BTS. It also assessed how BP mediated the direct relationship between MPS and BTS. The study used a quantitative method. Methods: A survey questionnaire was administered to collect data from 367 staff of regional blood banks and government university teaching hospital blood banks; and 213 were found to be usable. The main analysis was done using structural equation modeling. Results: This study found that MPS had a negative and insignificant relationship with the BTS. The study found that relationship between MPS and BP was positive and significant. The study also found that relationship between BP and BTS was positive and significant. The study concluded that the effect of MPS on BTS was fully mediated by BP. It was recommended that blood banks seeking to achieve transfusion sustainability must understand the sector in which they operate. The various stakeholders in the blood supply chain ie blood banks, hospital blood banks, funding agents, ministry of health, must also integrate to enhance the transfusion sustainability. Blood banks performance measures essentially timely delivery was very critical for saving lives of patients in need of blood. Conclusion: The study has provided a new conceptual framework that investigate the BP mediating effect on the relationship of MPS and BTS, and thus can serve as an incentive for more research to be conducted in this regard of different developing countries. The authors also proposed identifying the effect of other BP factors such as blood donor management and hospital transfusion practices on BTS.

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Toward a Sustainable Blood Supply in the United States: An Analysis of the Current System and Alternatives for the Future

Cited by 24 publications

References 20 publications

The mediation effect of total quality management on the relationship between master production schedul-ing and blood transfusion sustainability in Uganda

The mediation effect of total quality management on the relationship between master production schedul-ing and blood transfusion sustainability in Uganda

U.S. cities will not meet blood product resuscitation standards during major mass casualty incidents: Results of a THOR‐AABB working party prospective analysis

The mediation effect of blood production on the relationship between master production scheduling and transfusion sustainability in Uganda

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