Toward a neurobiology of temporal cognition: advances and challenges

Gibbon, John; Malapani, Chara; Dale, Corby L.; Gallistel, C. R.

doi:10.1016/s0959-4388(97)80005-0

Cited by 679 publications

(662 citation statements)

References 101 publications

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“…Because the durations relevant for movement (for instance in muscle phasing and coordination) fall within the sub-second range (Hore et al, 1991), it has been suggested these short intervals may be measured within the motor system. Observation that cerebellar lesions can lead to deficits in movement-related timing (Ivry & Keele, 1989;Ivry, Keele, & Diener, 1988) and in non-motor timing at the milliseconds range (Casini & Ivry, 1999) have combined to implicate this structure as a candidate locus for such processes (Ivry, 1996(Ivry, , 1997, but see also (Gibbon et al, 1997). Supporting this idea, network models have shown that the neural architecture of the cerebellum could feasibly measure sub-second intervals in a number of different ways (de Zeeuw et al, 1998;Guigon et al, 1994;Perrett, Ruiz, & Mauk, 1993).…”

Section: Activity Greater During the 06 S Intervalmentioning

confidence: 99%

“…For instance, psychophysical characteristics differ (Gibbon, Malapani, Dale, & Gallistel, 1997), pharmacological agents (Mitriani, Shekerdijiiski, Gourevitch, & Yanev, 1977;Rammsayer, 1999) and the distraction of attention in dual task scenarios (Rammsayer & Lima, 1991) can have differential influence (but see Macar, Grondin, & Casini, 1994), while lesions to specific brain areas elicit differential impairments (Clarke, Ivry, Grinband, Roberts, & Shimizu, 1996). Based on these observations, several authors (Gibbon et al, 1997;Hazeltine, 1997;Ivry, 1996;Lewis & Miall, 2003;Rammsayer, 1999) have hypothesised that time intervals in the millisecond and multisecond ranges are measured by independent brain mechanisms. Further, we have recently suggested (Lewis & Miall, 2003) that parts of the motor system may be involved in the automatic measurement of briefer durations, while flexible cognitive modules of the prefrontal and parietal cortex are recruited for the measurement of longer periods.…”

Section: Introductionmentioning

confidence: 99%

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Brain activation patterns during measurement of sub- and supra-second intervals

2003

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The possibility that different neural systems are used to measure temporal durations at the sub-second and several second ranges has been supported by pharmacological manipulation, psychophysics, and neural network modelling. Here, we add to this literature by using fMRI to isolate differences between the brain networks which measure 0.6 and 3 s in a temporal discrimination task with visual discrimination for control. We observe activity in bilateral insula and dorsolateral prefrontal cortex, and in right hemispheric pre-supplementary motor area, frontal pole, and inferior parietal cortex during measurement of both intervals, suggesting that these regions constitute a system used in temporal discrimination at both ranges. The frontal operculum, left cerebellar hemisphere and middle and superior temporal gyri, all show significantly greater activity during measurement of the shorter interval, supporting the hypotheses that the motor system is preferentially involved in the measurement of sub-second intervals, and that auditory imagery is preferentially used during measurement of the same. Only a few voxels, falling in the left posterior cingulate and inferior parietal lobe, are more active in the 3 s condition. Overall, this study shows that although many brain regions are used for the measurement of both sub-and supra-second temporal durations, there are also differences in activation patterns, suggesting that distinct components are used for the two durations.

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Section: Activity Greater During the 06 S Intervalmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Brain activation patterns during measurement of sub- and supra-second intervals

2003

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“…Electrophysiological, neuropharmacological, and lesion data, as well as imaging studies, have indicated that the neural correlate mediating duration processing consists of a network of distributed neural systems, involving cerebellum (Casini & Ivry, 1999;Ivry & Keele, 1989;Jueptner et al, 1995;Nichelli, Alway, & Grafman, 1996), basal ganglia (Gibbon, Malapani, Dale, Corby, & Gallistel, 1997;Hinton, Meck, & MacFall, 1996;Meck, 1996;Pastor, Artieda, Jahanshahi, & Obeso, 1992;Rammsayer, 1994;Rammsayer & Lima, 1990), parietal (Cabeza et al, 1997;Coull & Nobre, 1998), and prefrontal cortex (Casini & Ivry, 1999;Gibbon et al, 1997;Hinton et al, 1996;Nichelli, Clark, Hollnagel, & Grafman, 1995). Yet, for each of these structures there is little agreement on their functional contribution to duration processing and on their involvement in the processing of different time ranges (Gibbon et al, 1997;Ivry, 1996;Ivry & Keele, 1989;Jueptner et al, 1995;Meck, 1996;Nichelli et al, 1995;Rammsayer, 1994).…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

“…Yet, for each of these structures there is little agreement on their functional contribution to duration processing and on their involvement in the processing of different time ranges (Gibbon et al, 1997;Ivry, 1996;Ivry & Keele, 1989;Jueptner et al, 1995;Meck, 1996;Nichelli et al, 1995;Rammsayer, 1994). The precise functional role of the frontal cortex in particular is a subject of considerable controversy (Gibbon et al, 1997). Frontal lobe function has been brought in touch in different theories with clock or counter mechanisms (Grafman, 1989;Miall, 1996;Niki & Watanabe, 1979) as well as with the memory stage (Mangels, Ivry, & Shimizu, 1998;Nichelli et al, 1995).…”

Section: Introductionmentioning

confidence: 99%

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Processing of temporal duration information in working memory after frontodorsal tumour excisions

Hälbig

Cramon

Schmid

et al. 2002

Brain and Cognition

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This study aimed to test the hypothesis that impairments of temporal duration processing after frontal lobe lesions reflect deficits in executive monitoring functions rather than a domain-specific deficit in the maintenance of duration information in working memory. Patients with frontodorsal lesions, clinical controls with post-central lesions, and healthy controls performed recognition and classification tasks, which should allow for testing maintenance and monitoring functions, respectively. Results showed mild non-selective impairments of the frontal patients on both temporal and spatial recognition tasks, but a marked selective degradation on temporal classification while performance on spatial classification was unimpaired. This suggests that maintenance of duration information in working memory after frontal lesions is basically preserved but that, depending on executive task characteristics, there is a specific deficit in the strategic organization of this type of information.

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Neuropsychological mechanisms of interval timing behavior

2000

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Interval timing in the seconds-to-minutes range is believed to underlie a variety of complex behaviors in humans and other animals. One of the more interesting problems in interval timing is trying to understand how the brain times events lasting for minutes with millisecond-based neural processes. Timing models proposing the use of coincidence-detection mechanisms (e.g., the detection of simultaneous activity across multiple neural inputs) appear to be the most compatible with known neural mechanisms. From an evolutionary perspective, coincidence detection of neuronal activity may be a fundamental mechanism of timing that is expressed across a wide variety of species.

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Toward a neurobiology of temporal cognition: advances and challenges

Cited by 679 publications

References 101 publications

Brain activation patterns during measurement of sub- and supra-second intervals

Brain activation patterns during measurement of sub- and supra-second intervals

Processing of temporal duration information in working memory after frontodorsal tumour excisions

Neuropsychological mechanisms of interval timing behavior

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