2023
DOI: 10.1016/j.chom.2023.03.003
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Toward a global virus genomic surveillance network

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Cited by 26 publications
(40 citation statements)
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“…Enabling broader access to information from genomic surveillance for emerging and re-emerging pathogens has been and will remain a global health priority 12,17,19,[39][40][41][42] . In addition to the crucial work of building global sequencing capacity, methodological advances in how sequences are analyzed can address gaps in the surveillance landscape 12 .…”
Section: Discussionmentioning
confidence: 99%
“…Enabling broader access to information from genomic surveillance for emerging and re-emerging pathogens has been and will remain a global health priority 12,17,19,[39][40][41][42] . In addition to the crucial work of building global sequencing capacity, methodological advances in how sequences are analyzed can address gaps in the surveillance landscape 12 .…”
Section: Discussionmentioning
confidence: 99%
“…The PrimalSeq protocol uses a series of overlapping PCR amplicons generated with primers designed using PrimalScheme (https://primalscheme.com) to efficiently sequence virus genomes directly from clinical specimens [8,9]. Here, we used PrimalScheme to develop primer schemes for all four serotypes of dengue virus, which can be used with the amplicon-based sequencing protocols widely established during the COVID-19 pandemic [14]. We selected genetically diverse genomes within each of the dengue virus serotypes and then used PrimalScheme to generate four serotype-specific primer schemes ( Fig.…”
Section: Resultsmentioning
confidence: 99%
“…Moreover, a pan-serotype approach is needed to facilitate the sequencing of any serotype without the need for prior serotyping. Thus, designing a unified pan-serotype approach to sequence the global diversity of dengue virus, which fits within the established SARS-CoV-2 workflows, could rapidly accelerate the implementation of dengue virus genomic surveillance systems [14].…”
mentioning
confidence: 99%
“…The COVID-19 pandemic has highlighted the utility of genomic surveillance in tracking and monitoring the spread of viruses, detecting new variants, and informing public health interventions (Hill et al, 2023;Zeghbib et al, 2023). However, adapting routine sequencing into public health investigations will require additional programmatic investment in expertise and resources.…”
Section: The Role Of Xeno-monitoring Coupled With Metatranscriptomics...mentioning
confidence: 99%