Toupet fundoplication to prevent progression of scleroderma-associated interstitial lung damage: a study protocol
Alberto Aiolfi,
Davide Bona,
Michele Manara
et al.
Abstract:Summary
Background
Systemic sclerosis (SSc) is a rare autoimmune and multiorgan disorder. Hallmarks of the disease include inflammation, endothelial dysfunction, and dysregulation of fibroblasts leading to fibrosis of the skin and internal organs. The esophagus is often involved, with up to 80% of patients developing gastroesophageal reflux disease (GERD). Reflux can be associated with hiatal hernia and several complications such as erosive esophagitis, peptic stricture, Barrett’s e… Show more
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