Tough and hierarchical porous cryogel scaffolds preparation using n-butanol as a non-solvent

Sen, Tugce; Özçelık, Berrın; Ozmen, Mehmet Murat

doi:10.1080/00914037.2018.1452225

Cited by 13 publications

(10 citation statements)

References 50 publications

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“…To evaluate cross-linking efficiency of cryogels, gel fraction (W g , %) was calculated by: W g (%) = [(M dry /M 0 ) × 1/(0.05 × X MMT )] × 100 where M 0 is the weight of samples after preparation (g), M dry is the weight of dry specimens (g), and X MMT is the fraction ( w/v ) of MMT in the reaction medium [ 19 ].…”

Section: Methodsmentioning

confidence: 99%

“…To determine water retention capacity, equilibrium volume and weight swelling ratios of the samples with respect to dry states were calculated. The equilibrium weight-swelling ratio concerning dry states (q w ) of the samples was calculated as: q w = (M sw /M dry ) where M sw is the weight of swollen equilibrium cryogels (g) [ 19 ]. All measurements were repeated at least three times at room temperature.…”

Section: Methodsmentioning

confidence: 99%

“…The compression speed was adjusted at 0.1 mm s −1 , and tests were performed up to 80% compression of the original size of the samples in the swollen equilibrium state. The elastic modulus of each specimen was calculated by the slope of the initial linear part of the stress–strain curve [ 19 ].…”

Section: Methodsmentioning

confidence: 99%

“…Cryogels are prepared at temperatures below the freezing point of the gelation solvent, where solvent crystals are formed in the semi-frozen system. Subsequently, the reaction system is thawed, leaving micrometer sized large pores [ 18 , 19 ]. Although cryogels have superior swelling and mechanical properties, still a need arises to improve their performance.…”

Section: Introductionmentioning

confidence: 99%

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Highly Effective Covalently Crosslinked Composite Alginate Cryogels for Cationic Dye Removal

Sezen

Thakur

Ozmen

2021

Gels

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Currently, macroporous hydrogels have been receiving attention in wastewater treatment due to their unique structures. As a natural polymer, alginate is used to remove cationic dyes due to its sustainable features such as abundance, low cost, processability, and being environmentally friendly. Herein, alginate/montmorillonite composite macroporous hydrogels (cryogels) with high porosity, mechanical elasticity, and high adsorption yield for methylene blue (MB) were generated by the one-step cryogelation technique. These cryogels were synthesized by adding montmorillonite into gel precursor, followed by chemical cross-linking employing carbodiimide chemistry in a frozen state. The as-prepared adsorbents were analyzed by FT-IR, SEM, gel fraction, swelling, uniaxial compression, and MB adsorption tests. The results indicated that alginate/montmorillonite cryogels exhibited high gelation yield (up to 80%), colossal water uptake capacity, elasticity, and effective dye adsorption capacity (93.7%). Maximum adsorption capacity against MB was 559.94 mg g−1 by linear regression of Langmuir model onto experimental data. The Pseudo-Second-Order model was fitted better onto kinetic data compared to the Pseudo-First-Order model. Improved porosity and mechanical elasticity yielding enhanced dye removal capacity make them highly potential alternative adsorbents compared to available alginate/montmorillonite materials for MB removal.

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Highly Effective Covalently Crosslinked Composite Alginate Cryogels for Cationic Dye Removal

Sezen

Thakur

Ozmen

2021

Gels

Self Cite

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“…Although, a report by Macková et al outlines the benefits of graduated pore size distribution in hydrogels used in tissue engineering, since many human body tissues also exhibit a heterogeneous morphology [20]. This finding was further reiterated by Sen et al, who also explored heterogeneous pore size distribution for tissue engineering applications [21]. Cryostructuring, including directional freezing of cryogels, has been used to achieve varying degrees of porosity and aligned porosity or anisotropy within cryogels.…”

Section: Cryogel Propertiesmentioning

confidence: 99%

Cryogels: recent applications in 3D-bioprinting, injectable cryogels, drug delivery, and wound healing

Jones¹,

Williams²,

Boam³

et al. 2021

Beilstein J. Org. Chem.

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Cryogels are macroporous polymeric structures formed from the cryogelation of monomers/polymers in a solvent below freezing temperature. Due to their inherent interconnected macroporosity, ease of preparation, and biocompatibility, they are increasingly being investigated for use in biomedical applications such as 3D-bioprinting, drug delivery, wound healing, and as injectable therapeutics. This review highlights the fundamentals of macroporous cryogel preparation, cryogel properties that can be useful in the highlighted biomedical applications, followed by a comprehensive review of recent studies in these areas. Research evaluated includes the use of cryogels to combat various types of cancer, for implantation without surgical incision, and use as highly effective wound dressings. Furthermore, conclusions and outlooks are discussed for the use of these promising and durable macroporous cryogels.

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Tannic Acid Incorporated Antibacterial Polyethylene Glycol Based Hydrogel Sponges for Management of Wound Infections

Akin,

Akgul,

Tasdurmazli

et al. 2024

Macromolecular Bioscience

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Conventional wound dressings fail to provide features that can assist the healing process of chronic wounds. Multifunctional wound dressings address this issue by incorporating attributes including antibacterial and antioxidant activity, and the ability to enhance wound healing. Herein, polyethylene glycol‐based antibacterial hydrogel sponge dressings were prepared by a rapid and facile gas foaming method based on an acid chloride/alcohol reaction where tannic acid (TA) was included as a reactant to impart antibacterial efficacy as well as to enhance the mechanical properties of the samples. The results revealed that the TA‐integrated sponges possess excellent antibacterial properties against both E. coli and S. aureus with approximately 6–8 log reduction in the microbial colony count after 6 hours, indicating their high potential for management of infection‐prone wounds. Compared to the control sample, TA incorporation increased the elastic modulus by two‐fold. As the samples also exhibit biocompatibility, antioxidant activity and wound healing capacity, the novel TA‐incorporated hydrogels can be an alternative to traditional wound dressings for wounds with low‐to‐moderate exudate.This article is protected by copyright. All rights reserved

show abstract

Tough and hierarchical porous cryogel scaffolds preparation using n-butanol as a non-solvent

Cited by 13 publications

References 50 publications

Highly Effective Covalently Crosslinked Composite Alginate Cryogels for Cationic Dye Removal

Highly Effective Covalently Crosslinked Composite Alginate Cryogels for Cationic Dye Removal

Cryogels: recent applications in 3D-bioprinting, injectable cryogels, drug delivery, and wound healing

Tannic Acid Incorporated Antibacterial Polyethylene Glycol Based Hydrogel Sponges for Management of Wound Infections

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