Total Synthesis of Indole Alkaloid Alsmaphorazine D

Abstract

A concise total synthesis of rac‐alsmaphorazine D has been described for the first time. The efficient synthetic strategy features four key transformations: 1) a catalytic intramolecular oxidative cyclization for the δ‐lactamindole backbone; 2) an oxidative cyclic aminal formation for the hexahydropyrrolo[2,3‐b]pyrrole framework; 3) a transannular radical cyclization for the construction of the diazabicyclo[3.3.1]nonane structure; and 4) a one‐pot desilylation/double epimerization reaction that affirms the relative stereochemistry.

Electrochemical Dearomatizing Spirocyclization of Alkynes with Dimethyl 2-Benzylmalonates to Spiro[4.5]deca-trienones

“…1,3-Dicarbonyl compounds are common and readily available organics, which can be used to construct complex natural products . The 1,3-dicarbonyl carbon-centered radicals generated by anodic oxidation of C–H bonds can react with unsaturated π-system.…”

Synthesis of NH2‐MIL‐125/NH2‐MIL‐125‐P@TiO2 and Its Adsorption to Uranyl Ions

“…It is often used as an adsorbent for radionuclides, but its surface functional groups are few, and its adsorption capacity for uranyl ions is low. [43] The phosphoric acid group [44,45,46,47] has strong coordination ability with uranyl ions. By loading titanium dioxide on NH 2 -MIL-125 and phosphorylating it in situ, [48,49,50] the functionally improved phosphorylated NH 2 -MIL-125@titanium dioxide was obtained, and the adsorption performance of the material for uranyl ions in aqueous solution was explored.…”