Abstract:The discorhabdin natural products are a large subset of pyrroloiminoquinone alkaloids with a myriad of biological activities. Despite garnering much synthetic attention, few members have thus far been completed, particularly those featuring a bridging carbon–nitrogen bond that is found in numerous discorhabdins, including discorhabdin V. Here we report the first total synthesis and full stereochemical assignment of (+)‐discorhabdin V. To access the pyrroloiminoquinone we developed a convergent N‐alkylation/oxi… Show more
Pyrroloiminoquinone alkaloids are a large class of natural products that display a wide range of biological activities. Synthetic approaches to these natural products typically rely on a common late-stage C10-oxygenated...
Pyrroloiminoquinone alkaloids are a large class of natural products that display a wide range of biological activities. Synthetic approaches to these natural products typically rely on a common late-stage C10-oxygenated...
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