Abstract:Described herein is ac oncise total synthesis of the highly potent nicotinic acetylcholine receptor ligand hosieine A in racemic and enantioenriched forms.T he synthesis requires only seven steps and features at elescoped reaction sequence initiated by ag old-catalyzed Rautenstrauchreaction.Supportinginformation and the ORCID identification number(s) for the author(s) of this article can be found under: https://doi.Scheme 2. Seven-step synthesis of (AE)-2.D CM = dichloromethane, LDA = lithium diisopropylamide,… Show more
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