2023
DOI: 10.3762/bjoc.19.36
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Total synthesis: an enabling science

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“…Despite recurrent criticism regarding its supposed decline, it is “ as exciting as ever and here to stay ”, as stated by Baran . Not only is it the testing ground for new methods and strategies in organic synthesis, but it also serves the fields of phytochemistry, marine natural products, bacteriologythrough structure elucidationand medicinal chemistry as the first move in many drug discovery campaigns . Moreover, total synthesis could be considered as a showcase of progress made in the field of organic synthesis.…”
Section: Introductionmentioning
confidence: 99%
“…Despite recurrent criticism regarding its supposed decline, it is “ as exciting as ever and here to stay ”, as stated by Baran . Not only is it the testing ground for new methods and strategies in organic synthesis, but it also serves the fields of phytochemistry, marine natural products, bacteriologythrough structure elucidationand medicinal chemistry as the first move in many drug discovery campaigns . Moreover, total synthesis could be considered as a showcase of progress made in the field of organic synthesis.…”
Section: Introductionmentioning
confidence: 99%