Total Syntheses of Conhydrines via Ruthenium-Catalyzed Ring-Closing Metathesis (RCM) Reactions

Abstract

Conhydrines are extremely interesting target molecules in organic synthesis because of their unique structural motifs and potent bioactivities. The ring-closing metathesis (RCM) reaction has received considerable attention for a long time. In this review, we highlight 13 total syntheses of conhydrines by using RCM reaction as the key step from different research groups during the period 2000 to 2021.